Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Viktor M. Pastukh"'
Autor:
Larysa V. Yuzefovych, Viktor M. Pastukh, Madhuri S. Mulekar, Kate Ledbetter, William O. Richards, Lyudmila I. Rachek
Publikováno v:
Biomedicines, Vol 11, Iss 9, p 2514 (2023)
While improvement of mitochondrial function after bariatric surgery has been demonstrated, there is limited evidence about the effects of bariatric surgery on circulatory cell-free (cf) mitochondrial DNA (mtDNA) and intracellular mtDNA abundance. Pla
Externí odkaz:
https://doaj.org/article/d89f4872b4f34fdea77fe06447f0b1bf
Autor:
Grant T. Daly, Viktor M. Pastukh, Yong B. Tan, C. Michael Francis, C. Zack Aggen, S. Chris Groark, Carson Edwards, Madhuri S. Mulekar, Mohammad Hamo, Jon D. Simmons, Matthew E. Kutcher, Emily M. Hartsell, Darrell L. Dinwiddie, Zachary M. Turpin, Hank W. Bass, Justin T. Roberts, Mark N. Gillespie, Raymond J. Langley
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 10, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/4c19c86930224c669d880a5a57da76ec
Autor:
Ji Young Lee, Reece P. Stevens, Viktoriya V Pastukh, Viktor M Pastukh, Natalya Kozhukhar, Mikhail F. Alexeyev, Julie A Reisz, David Nerguizian, Angelo D'Alessandro, Anna Koloteva, Meredith S. Gwin, Justin T Roberts, Glen M Borchert, Brant M. Wagener, Jean-François Pittet, Brian B Graham, Kurt R Stenmark, Troy Stevens
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology.
Autor:
Larysa V Yuzefovych, Viktor M Pastukh, Mykhaylo V Ruchko, Jon D Simmons, William O Richards, Lyudmila I Rachek
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0222278 (2019)
Cells damaged by mechanical or infectious injury release proinflammatory mitochondrial DNA (mtDNA) fragments into the circulation. We evaluated the relation between plasma levels of mtDNA fragments in obese type 2 diabetes mellitus (T2DM) patients an
Externí odkaz:
https://doaj.org/article/e4fdbab1eb4b471b85614f0c42ea8360
Publikováno v:
International Journal of COPD, Vol 2011, Iss default, Pp 209-219 (2011)
Viktor M Pastukh1, Li Zhang2, Mykhaylo V Ruchko1, Olena Gorodnya1, Gina C Bardwell1, Rubin M Tuder2, Mark N Gillespie11Department of Pharmacology and Center for Lung Biology, University of South Alabama College of Medicine, Mobile, AL, USA; 2Program
Externí odkaz:
https://doaj.org/article/40093cf3101f4320806ab4b3b6aff2f3
Publikováno v:
Diabetes. 70
Ogg1 (8-oxoguanine DNA glycosylase-1) is a DNA glycosylase mediating the first step in the base excision repair which removes 8-oxoguanine and repairs oxidized nuclear and mitochondrial (mtDNA). Obesity-induced mtDNA damage heightens mitochondrial ox
Autor:
Viktor M. Pastukh, Jeffrey D. Kerby, Richard R. Rieske, Gina C. Capley, Mark N. Gillespie, Jon P. Audia, Alison Smith, Jon D. Simmons, Yong B. Tan, Danielle Tatum, Juan Duchesne, Matthew E. Kutcher
Publikováno v:
J Am Coll Surg
BACKGROUND: Stored plasma products are widely regarded as being functionally acellular, obviating the need for leukoreduction. We tested the hypothesis that donor plasma is contaminated by leukocytes and platelets, which, after frozen storage, would
Autor:
Tiago N. Machuca, Olena M. Gorodnya, Viktor M. Pastukh, Mark N. Gillespie, Glenn L. Wilson, Thomas M. Beaver, Yong B. Tan, Jon D. Simmons, Madhuri S. Mulekar
Publikováno v:
J Surg Res
Background Transplantation of lungs procured after donation after circulatory death (DCD) is challenging because postmortem metabolic degradation may engender susceptibility to ischemia–reperfusion (IR) injury. Because oxidative mitochondrial DNA (
Publikováno v:
Free Radical Biology and Medicine. 96:78-88
Mitochondria of mammalian cells contain multiple copies of mitochondrial (mt) DNA. Although mtDNA copy number can fluctuate dramatically depending on physiological and pathophysiologic conditions, the mechanisms regulating mitochondrial genome replic
Autor:
Mita Patel, Viktor M. Pastukh, David W. Clark, Gina C. Bardwell, Abu-Bakr Al-Mehdi, Mark N. Gillespie, Justin T Roberts, Glen M. Borchert
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 309:L1367-L1375
In hypoxia, mitochondria-generated reactive oxygen species not only stimulate accumulation of the transcriptional regulator of hypoxic gene expression, hypoxia inducible factor-1 (Hif-1), but also cause oxidative base modifications in hypoxic respons