Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Viktor J Olah"'
Autor:
Viktor J Olah, Annie M Goettemoeller, Sruti Rayaprolu, Eric B Dammer, Nicholas T Seyfried, Srikant Rangaraju, Jordane Dimidschstein, Matthew JM Rowan
Publikováno v:
eLife, Vol 11 (2022)
In Alzheimer’s disease (AD), a multitude of genetic risk factors and early biomarkers are known. Nevertheless, the causal factors responsible for initiating cognitive decline in AD remain controversial. Toxic plaques and tangles correlate with prog
Externí odkaz:
https://doaj.org/article/48d3ee7817ef4b4e91c5efc05739463b
Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology
Autor:
Annie M. Goettemoeller, Emmie Banks, Prateek Kumar, Viktor J. Olah, Katharine E. McCann, Kelly South, Christina C. Ramelow, Anna Eaton, Duc M. Duong, Nicholas T. Seyfried, David Weinshenker, Srikant Rangaraju, Matthew J. M. Rowan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Preventative treatment for Alzheimer’s Disease (AD) is dire, yet mechanisms underlying early regional vulnerability remain unknown. In AD, one of the earliest pathophysiological correlates to cognitive decline is hyperexcitability, which i
Externí odkaz:
https://doaj.org/article/472c8a45309c4ce99d27485c1bbd846b
Independent automated scoring of sleep-wake and seizures have recently been achieved; however, the combined scoring of both states has yet to be reported. Mouse models of epilepsy typically demonstrate an abnormal electroencephalographic (EEG) backgr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52c02295cb152743c4b8b7123b8a5ebc
https://doi.org/10.1101/2023.04.07.536063
https://doi.org/10.1101/2023.04.07.536063
Autor:
Annie M Goettemoeller, Viktor J Olah, Sruti Rayaprolu, Eric B Dammer, Nicholas T Seyfried, Srikant Rangaraju, Jordane Dimidschstein, Matthew JM Rowan
Publikováno v:
eLife. 11
In Alzheimer’s disease (AD), a multitude of genetic risk factors and early biomarkers are known. Nevertheless, the causal factors responsible for initiating cognitive decline in AD remain controversial. Toxic plaques and tangles correlate with prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0130f9f7fa3436087c675b7d6c1738a
https://doi.org/10.7554/elife.75316
https://doi.org/10.7554/elife.75316
Autor:
Annie M Goettemoeller, Viktor J Olah, Sruti Rayaprolu, Eric B Dammer, Nicholas T Seyfried, Srikant Rangaraju, Jordane Dimidschstein, Matthew JM Rowan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cc80aa748de97f2ad4bab58686ecfae
https://doi.org/10.7554/elife.75316.sa2
https://doi.org/10.7554/elife.75316.sa2
Autor:
Viktor J, Olah, Annie M, Goettemoeller, Sruti, Rayaprolu, Eric B, Dammer, Nicholas T, Seyfried, Srikant, Rangaraju, Jordane, Dimidschstein, Matthew J M, Rowan
Publikováno v:
eLife. 11
In Alzheimer's disease (AD), a multitude of genetic risk factors and early biomarkers are known. Nevertheless, the causal factors responsible for initiating cognitive decline in AD remain controversial. Toxic plaques and tangles correlate with progre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6dda09026420668daf99165f016ebf58
https://pubmed.ncbi.nlm.nih.gov/35727131
https://pubmed.ncbi.nlm.nih.gov/35727131
Publikováno v:
eLife, Vol 11 (2022)
Understanding the activity of the mammalian brain requires an integrative knowledge of circuits at distinct scales, ranging from ion channel gating to circuit connectomics. Computational models are regularly employed to understand how multiple parame
Externí odkaz:
https://doaj.org/article/428865a5969147dd882ac425225b44a4