Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Viktor Horvath"'
Autor:
Zohreh Izadifar, Justin Cotton, Siyu Chen, Viktor Horvath, Anna Stejskalova, Aakanksha Gulati, Nina T. LoGrande, Bogdan Budnik, Sanjid Shahriar, Erin R. Doherty, Yixuan Xie, Tania To, Sarah E. Gilpin, Adama M. Sesay, Girija Goyal, Carlito B. Lebrilla, Donald E. Ingber
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Modulation of the cervix by steroid hormones and commensal microbiome play a central role in the health of the female reproductive tract. Here we describe organ-on-a-chip (Organ Chip) models that recreate the human cervical epithelial-stroma
Externí odkaz:
https://doaj.org/article/0c123d582c57457d8c8042d389f2b87d
Autor:
James Logue, Arup R. Chakraborty, Robert Johnson, Girija Goyal, Melissa Rodas, Louis J. Taylor, Lauren Baracco, Marisa E. McGrath, Robert Haupt, Brooke A. Furlong, Mercy Soong, Pranav Prabhala, Viktor Horvath, Kenneth E. Carlson, Stuart Weston, Donald E. Ingber, Melvin L. DePamphilis, Matthew B. Frieman
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)
Compound-testing in a murine model for COVID-19 show that the prophylactic or therapeutic application of Apilimod and other PIKfyve inhibitors, the former being considered for human Phase II trials, worsens disease outcome with higher lung viral load
Externí odkaz:
https://doaj.org/article/9de19b41ea5f445cb565a156c6a567d3
Autor:
Megan M Sperry, Tomiko T Oskotsky, Ivana Marić, Shruti Kaushal, Takako Takeda, Viktor Horvath, Rani K Powers, Melissa Rodas, Brooke Furlong, Mercy Soong, Pranav Prabhala, Girija Goyal, Kenneth E Carlson, Ronald J Wong, Idit Kosti, Brian L Le, James Logue, Holly Hammond, Matthew Frieman, David K Stevenson, Donald E Ingber, Marina Sirota, Richard Novak
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 5, p e1011050 (2023)
Drug repurposing requires distinguishing established drug class targets from novel molecule-specific mechanisms and rapidly derisking their therapeutic potential in a time-critical manner, particularly in a pandemic scenario. In response to the chall
Externí odkaz:
https://doaj.org/article/cfab81f7026e481d8f6ae5a6eade32cd
Autor:
Zsofia Dohy, Andras Vereckei, Viktor Horvath, Csilla Czimbalmos, Liliana Szabo, Attila Toth, Ferenc I. Suhai, Ibolya Csecs, David Becker, Bela Merkely, Hajnalka Vago
Publikováno v:
Annals of Noninvasive Electrocardiology, Vol 25, Iss 5, Pp n/a-n/a (2020)
Abstract Background Structural myocardial changes in hypertrophic cardiomyopathy (HCM) are associated with different abnormalities on electrocardiographs (ECGs). The diagnostic value of the ECG voltage criteria used to screen for left ventricular hyp
Externí odkaz:
https://doaj.org/article/911b1272c4ea4de2badc00670298e58e
Autor:
Elee Shimshoni, Gwenn E. Merry, Zachary D. Milot, Crystal Yuri Oh, Viktor Horvath, Russell A. Gould, Joseph A. Caruso, Chira Chen-Tanyolac, Philippe Gascard, Veena Sangwan, Julie Bérubé, Swneke D. Bailey, Sean Hall, Matthew D. Stachler, Lorenzo Ferri, Thea D. Tlsty, Donald E. Ingber
Publikováno v:
Gastro Hep Advances.
Autor:
Zohreh Izadifar, Justin Cotton, Cathy Chen, Nicole A. Bustos, Viktor Horvath, Anna Stejskalova, Chloe Wu, Aakanksha Gulati, Nina T. LoGrande, Erin Dohetry, Tania To, Sarah E. Gilpin, Adama M. Sesay, Girija Goyal, Katharina Ribbeck, Carlito Lebrilla, Donald E. Ingber
Modulation of mucus production by the human ecto- and endo-cervical epithelium by steroid hormones and associated interactions with commensal microbiome play a central role in the physiology and pathophysiology of the female reproductive tract. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7cd9d9d1276393cb08fde73ed12ba60
https://doi.org/10.1101/2023.02.22.529436
https://doi.org/10.1101/2023.02.22.529436
Autor:
James Logue, Arup R. Chakraborty, Robert Johnson, Girija Goyal, Louis J. Taylor, Lauren Baracco, Marisa E. McGrath, Robert Haupt, Melissa Rodas, Brooke A. Furlong, Mercy Soong, Pranav Prabhala, Viktor Horvath, Kenneth E. Carlson, Stuart Weston, Donald E. Ingber, Melvin L. DePamphilis, Matthew B. Frieman
The ongoing COVID-19 pandemic has claimed more than 6 million lives and continues to test the world economy and healthcare systems. To combat this pandemic, the biological research community has shifted efforts to the development of medical counterme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66c0b407f9cfce5cffaed88bdf9aece6
https://doi.org/10.21203/rs.3.rs-1605065/v1
https://doi.org/10.21203/rs.3.rs-1605065/v1
Autor:
Megan M. Sperry, Tomiko Oskotsky, Ivana Marić, Shruti Kaushal, Takako Takeda, Viktor Horvath, Rani K. Powers, Melissa Rodas, Brooke Furlong, Mercy Soong, Pranav Prabhala, Girija Goyal, Kenneth E. Carlson, Ronald J. Wong, Idit Kosti, Brian L. Le, James Logue, Holly Hammond, Matthew Frieman, David K. Stevenson, Donald E. Ingber, Marina Sirota, Richard Novak
Publikováno v:
medRxiv
PLoS computational biology, vol 19, iss 5
PLoS computational biology, vol 19, iss 5
SummaryImportanceDrug repurposing requires distinguishing established drug class targets from novel molecule-specific mechanisms and rapidly derisking their therapeutic potential in a time-critical manner, particularly in a pandemic scenario. In resp
Autor:
Seongmin Kim, Arash Naziripour, Pranav Prabhala, Viktor Horváth, Abidemi Junaid, David T. Breault, Girija Goyal, Donald E. Ingber
Publikováno v:
EBioMedicine, Vol 99, Iss , Pp 104921- (2024)
Summary: Background: Sulfadoxine-pyrimethamine (SP) antimalarial therapy has been suggested to potentially increase the birth weight of infants in pregnant women in sub-Saharan Africa, independently of malarial infection. Here, we utilized female int
Externí odkaz:
https://doaj.org/article/1052d97ecf594f1d99ffcccef20f927c
Autor:
Gautam Mahajan, Erin Doherty, Tania To, Arlene Sutherland, Jennifer Grant, Abidemi Junaid, Aakanksha Gulati, Nina LoGrande, Zohreh Izadifar, Sanjay Sharma Timilsina, Viktor Horváth, Roberto Plebani, Michael France, Indriati Hood-Pishchany, Seth Rakoff-Nahoum, Douglas S. Kwon, Girija Goyal, Rachelle Prantil-Baun, Jacques Ravel, Donald E. Ingber
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-18 (2022)
Abstract Background A dominance of non-iners Lactobacillus species in the vaginal microbiome is optimal and strongly associated with gynecological and obstetric health, while the presence of diverse obligate or facultative anaerobic bacteria and a pa
Externí odkaz:
https://doaj.org/article/738d72b5adf94c56a245f3fe34145f30