Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Viktor Bugajev"'
Autor:
Livia Demkova, Viktor Bugajev, Miroslava K. Adamcova, Ladislav Kuchar, Srdjan Grusanovic, Meritxell Alberich-Jorda, Petr Draber, Ivana Halova
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
ORMDL3 is a prominent member of a family of highly conserved endoplasmic reticulum resident proteins, ORMs (ORM1 and ORM2) in yeast, dORMDL in Drosophila and ORMDLs (ORMDL1, ORMDL2, and ORMDL3) in mammals. ORMDL3 mediates feedback inhibition of de no
Externí odkaz:
https://doaj.org/article/ef0f3f88e59d4b57aa7ffd74f3a816cd
Autor:
Livia Demkova, Viktor Bugajev, Pavol Utekal, Ladislav Kuchar, Björn Schuster, Petr Draber, Ivana Halova
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract In mammals, the ORMDL family of evolutionarily conserved sphingolipid regulators consists of three highly homologous members, ORMDL1, ORMDL2 and ORMDL3. ORMDL3 gene has been associated with childhood-onset asthma and other inflammatory disea
Externí odkaz:
https://doaj.org/article/ed0a725632d54499a5c148e419aa8fe6
Autor:
Viktor Bugajev, Lubica Draberova, Pavol Utekal, Michaela Blazikova, Magda Tumova, Petr Draber
Publikováno v:
Cells, Vol 12, Iss 16, p 2069 (2023)
Signal transduction by the high-affinity IgE receptor (FcεRI) depends on membrane lipid and protein compartmentalization. Recently published data show that cells treated with 1-heptanol, a cell membrane fluidizer, exhibit changes in membrane propert
Externí odkaz:
https://doaj.org/article/09c54b8a539640a38f007e2b9919ad95
Autor:
Viktor Bugajev, Ivana Halova, Livia Demkova, Sara Cernohouzova, Petra Vavrova, Michal Mrkacek, Pavol Utekal, Lubica Draberova, Ladislav Kuchar, Björn Schuster, Petr Draber
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
The systemic anaphylactic reaction is a life-threatening allergic response initiated by activated mast cells. Sphingolipids are an essential player in the development and attenuation of this response. De novo synthesis of sphingolipids in mammalian c
Externí odkaz:
https://doaj.org/article/dbc9dbc7f9304aafa2a4b34fc56d60ed
Autor:
Viktor Bugajev, Tomas Paulenda, Pavol Utekal, Michal Mrkacek, Ivana Halova, Ladislav Kuchar, Ondrej Kuda, Petra Vavrova, Björn Schuster, Sergio Fuentes-Liso, Lucie Potuckova, Daniel Smrz, Sara Cernohouzova, Lubica Draberova, Monika Bambouskova, Petr Draber
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100121- (2021)
Leukotrienes (LTs) and sphingolipids are critical lipid mediators participating in numerous cellular signal transduction events and developing various disorders, such as bronchial hyperactivity leading to asthma. Enzymatic reactions initiating produc
Externí odkaz:
https://doaj.org/article/058a630f0eee440cb9b82b31fbd5f3ff
Autor:
Lubica Draberova, Tomas Paulenda, Ivana Halova, Lucie Potuckova, Viktor Bugajev, Monika Bambouskova, Magda Tumova, Petr Draber
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144596 (2015)
Ethanol has multiple effects on biochemical events in a variety of cell types, including the high-affinity immunoglobulin E receptor (FcεRI) signaling in antigen-activated mast cells. However, the underlying molecular mechanism remains unknown. To g
Externí odkaz:
https://doaj.org/article/b80b828ae57f47ab897b2cee161bd25f
Autor:
Pavol Utekal, Lucie Potuckova, Lubica Dráberová, Tomas Paulenda, Michal Mrkacek, Ivana Halova, Ondrej Kuda, Monika Bambouskova, Petr Dráber, Petra Vavrova, Björn Schuster, Daniel Smrz, Viktor Bugajev, Sara Cernohouzova, Sergio Fuentes-Liso, Ladislav Kuchar
Publikováno v:
Journal of Lipid Research, Vol 62, Iss, Pp 100121-(2021)
Journal of Lipid Research
Journal of Lipid Research
Leukotrienes (LTs) and sphingolipids are critical lipid mediators participating in numerous cellular signal transduction events and developing various disorders, such as bronchial hyperactivity leading to asthma. Enzymatic reactions initiating produc
Autor:
Björn Schuster, Livia Demkova, Lubica Dráberová, Ivana Halova, Ladislav Kuchar, Pavol Utekal, Petra Vavrova, Viktor Bugajev, Petr Dráber, Michal Mrkacek, Sara Cernohouzova
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2021)
Frontiers in Immunology, Vol 11 (2021)
The systemic anaphylactic reaction is a life-threatening allergic response initiated by activated mast cells. Sphingolipids are an essential player in the development and attenuation of this response. De novo synthesis of sphingolipids in mammalian c
Publikováno v:
Science Signaling. 11
Chemotaxis of mast cells is one of the crucial steps in their development and function. Non-T cell activation linker (NTAL) is a transmembrane adaptor protein that inhibits the activation of mast cells and B cells in a phosphorylation-dependent manne
Autor:
Lubica Dráberová, Petr Dráber, Aivi Doan, Gautam Goel, Iva Polakovicova, Agnes Gardet, Monika Bambouskova, Ivana Halova, Pavol Utekal, Viktor Bugajev, Ramnik J. Xavier
Publikováno v:
Molecular and Cellular Biology. 36:1366-1382
Aggregation of the high-affinity receptor for IgE (FcεRI) in mast cells initiates activation events that lead to degranulation and release of inflammatory mediators. To better understand the signaling pathways and genes involved in mast cell activat