Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Viktor A. Timoshnikov"'
Publikováno v:
Molecules, Vol 28, Iss 10, p 4210 (2023)
Omadine or N-hydroxypyridine-2-thione and its metal complexes are widely used in medicine and show bactericidal, fungicidal, anticancer, and photochemical activity. The redox activity of omadine complexes with iron, copper, and zinc on lipid peroxida
Externí odkaz:
https://doaj.org/article/aca36baea2d14262b14e712e46048c0c
Autor:
Viktor A. Timoshnikov, Olga Yu. Selyutina, Nikolay E. Polyakov, Victoria Didichenko, George J. Kontoghiorghes
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1247 (2022)
The antioxidant/pro-oxidant activity of drugs and dietary molecules and their role in the maintenance of redox homeostasis, as well as the implications in health and different diseases, have not yet been fully evaluated. In particular, the redox acti
Externí odkaz:
https://doaj.org/article/a6b4aa7b14b842e98d1ab1d6c2fdc5fa
Autor:
Viktor A. Timoshnikov, Lilia A. Kichigina, Olga Yu. Selyutina, Nikolay E. Polyakov, George J. Kontoghiorghes
Publikováno v:
Molecules, Vol 26, Iss 16, p 5064 (2021)
Deferasirox is an orally active, lipophilic iron chelating drug used on thousands of patients worldwide for the treatment of transfusional iron overload. The essential transition metals iron and copper are the primary catalysts of reactive oxygen spe
Externí odkaz:
https://doaj.org/article/4efdc13037c84e568e209a18a9f48b48
Autor:
George J. Kontoghiorghes, Annita Kolnagou, Christina N. Kontoghiorghe, Loukia Mourouzidis, Viktor A. Timoshnikov, Nikolay E. Polyakov
Publikováno v:
Medicines, Vol 7, Iss 8, p 45 (2020)
Iron and ascorbic acid (vitamin C) are essential nutrients for the normal growth and development of humans, and their deficiency can result in serious diseases. Their interaction is of nutritional, physiological, pharmacological and toxicological int
Externí odkaz:
https://doaj.org/article/7e9f4227d1704608ac7294a8320f50fd
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 11, p 3967 (2020)
Ascorbic acid (AscH2) is one of the most important vitamins found in the human diet, with many biological functions including antioxidant, chelating, and coenzyme activities. Ascorbic acid is also widely used in medical practice especially for increa
Externí odkaz:
https://doaj.org/article/a3e8593f4d1742f79f7dab3392b3f56d
Autor:
Maxim V. Zelikman, Yuri I. Glazachev, Anna A. Schlotgauer, Polina A. Kononova, Nikolay E. Polyakov, Viktor A. Timoshnikov, Olga Yu. Selyutina, Mikhail V. Khvostov, Ekaterina A. Shelepova
Publikováno v:
The Journal of Membrane Biology. 253:343-356
The effect of the natural saponin glycyrrhizic acid (GA) and polysaccharide arabinogalactan (AG) on the transmembrane potential of rat thymocytes was investigated using the potential-sensitive fluorescent probe 4-(p-dimethylaminostyryl)-1-methylpyrid
Autor:
George J. Kontoghiorghes, Olga Yu. Selyutina, Lilia A Kichigina, Nikolay E. Polyakov, Viktor A. Timoshnikov
Publikováno v:
Molecules, Vol 26, Iss 5064, p 5064 (2021)
Molecules
Volume 26
Issue 16
Molecules
Volume 26
Issue 16
Deferasirox is an orally active, lipophilic iron chelating drug used on thousands of patients worldwide for the treatment of transfusional iron overload. The essential transition metals iron and copper are the primary catalysts of reactive oxygen spe
Autor:
Olga Yu. Selyutina, Viktor A. Timoshnikov, T.V. Kobzeva, Nikolay E. Polyakov, George J. Kontoghiorghes
Publikováno v:
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 24(3)
Copper ions can catalyze the production of free oxygen radicals (•OH and •OOH) similar to iron ions. The capacity to initiate oxidative damage is most commonly attributed to Cu-induced toxicity in copper-related diseases where there is an increas
Autor:
Annita Kolnagou, George J. Kontoghiorghes, Viktor A. Timoshnikov, Loukia Mourouzidis, Christina N Kontoghiorghe, Nikolay E. Polyakov
Publikováno v:
Medicines, Vol 7, Iss 45, p 45 (2020)
Medicines
Medicines
Iron and ascorbic acid (vitamin C) are essential nutrients for the normal growth and development of humans, and their deficiency can result in serious diseases. Their interaction is of nutritional, physiological, pharmacological and toxicological int
Publikováno v:
Journal of Photochemistry and Photobiology A: Chemistry. 289:14-21
Deferiprone (L1) is an effective iron chelating drug which is widely used for the treatment of iron overload diseases. Although L1 itself does not absorb visible light, the absorption spectra of its Fe(III) complexes exhibit intensive absorption band