Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Vikte Lionikaite"'
Autor:
Petra Henning, Ali Kassem, Anna Westerlund, Pernilla Lundberg, Cecilia Engdahl, Vikte Lionikaite, Pernilla Wikström, Jianyao Wu, Lei Li, Catharina Lindholm, Pedro P. C. de Souza, Sofia Movérare-Skrtic, Ulf H. Lerner
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
It is well established that inflammatory processes in the vicinity of bone often induce osteoclast formation and bone resorption. Effects of inflammatory processes on bone formation are less studied. Therefore, we investigated the effect of locally i
Externí odkaz:
https://doaj.org/article/336269047b1142138c0c06e32ee49a03
Autor:
Karin Horkeby, Helen H. Farman, Sofia Movérare-Skrtic, Vikte Lionikaite, Jianyao Wu, Petra Henning, Sara Windahl, Klara Sjögren, Claes Ohlsson, Marie K. Lagerquist
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Estrogen receptor alpha (ERα) signaling has beneficial skeletal effects in males. ERα signaling also affects other tissues, and to find bone-specific treatments, more knowledge regarding tissue-specific ERα signaling is needed. ERα is su
Externí odkaz:
https://doaj.org/article/6b71bfb25f684c21a71531ff64572d44
Autor:
Antti Koskela, Karin Gustafsson, Vikte Lionikaite, Claes Ohlsson, Klara Sjögren, I. Wernstedt Asterholm, Louise Grahnemo, Juha Tuukkanen, Petra Henning, Marie K Lagerquist
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 315:E1274-E1285
Mice with impaired acute inflammatory responses within adipose tissue display reduced diet-induced fat mass gain associated with glucose intolerance and systemic inflammation. Therefore, acute adipose tissue inflammation is needed for a healthy expan
Autor:
Karin H Nilsson, Vikte Lionikaite, Karin Gustafsson, Sofia Movérare-Skrtic, Cecilia Engdahl, Claes Ohlsson, Marie K Lagerquist, Petra Henning, Helen H. Farman, Lina Lawenius
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 320(1)
Mutation of arginine 264 in ERα has been shown to abrogate rapid membrane ERα-mediated endothelial effects. Our novel finding that mutation of R264 is dispensable for ERα-mediated skeletal effects supports the concept that R264 determines tissue s
Autor:
Pierre Chambon, Petra Henning, Helen H. Farman, Marie K Lagerquist, Annica Andersson, Angelina I. Bernardi, Karin Gustafsson, Vikte Lionikaite, Klara Sjögren, Claes Ohlsson, Ulrika Islander, Sofia Movérare-Skrtic
Publikováno v:
Journal of the Endocrine Society
Estrogen treatment increases bone mass and reduces fat mass but is associated with adverse effects in postmenopausal women. Knowledge regarding tissue-specific estrogen signaling is important to aid the development of new tissue-specific treatments.
Publikováno v:
Journal of Leukocyte Biology. 104:1133-1145
Increased intake of vitamin A (retinoids) is associated with decreased bone mass and increased fracture risk in humans. Mechanistic studies in rodents have shown that hypervitaminosis A results in decreased bone mass caused by an increase in perioste
Autor:
Angelina I. Bernardi, Anna E. Törnqvist, Claes Ohlsson, Pierre Chambon, Sofia Movérare-Skrtic, Marie K Lagerquist, Helen H. Farman, Petra Henning, Vikte Lionikaite, Annica Andersson, Karin Gustafsson, Ulrika Islander, Matti Poutanen, Klara Sjögren
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 34(12)
Estrogen treatment increases bone mass and reduces fat mass but is associated with adverse effects in postmenopausal women. Knowledge regarding tissue-specific estrogen signaling is important to aid the development of new tissue-specific treatments.
Autor:
Jérôme Nicod, Joseph Wood, Jean-Marie Launay, Benjamin K Yee, Arimantas Lionikas, Connie R. Bezzina, Amarjit Bhomra, Jacques Callebert, Robert W. Davies, Martin Fray, Tertius Hough, Cormac Cosgrove, Barbara Nell, Leo Goodstadt, Elisabeth M. Lodder, Richard Mott, Hayley Phelps, Jonathan Flint, Paul Klenerman, Vikte Lionikaite, Paul Franken, Steve D. M. Brown, Paul Potter, Carl Hassett, Yigal M. Pinto, Sara Wells, Alison Walling, Richard M. Aspden, Nasrin Bopp, Russell Joynson, David J. Adams, Jennifer S. Gregory, Rebecca E. McIntyre, Nick P. Talbot, Tom Weaver, Na Cai, David A. Blizard, Mark Harrison, Polinka Hernandez-Pliego, Carol Ann Remme, Peter A. Robbins, Clare Rowe
Publikováno v:
Nature genetics, 48(8), 912-918. Nature Publishing Group
Nature genetics
Nature Genetics
Nature Genetics, vol. 48, no. 8, pp. 912-918
Nature genetics
Nature Genetics
Nature Genetics, vol. 48, no. 8, pp. 912-918
Two bottlenecks impeding the genetic analysis of complex traits in rodents are access to mapping populations able to deliver gene-level mapping resolution and the need for population-specific genotyping arrays and haplotype reference panels. Here we
Autor:
Juha Tuukkanen, Vikte Lionikaite, Helen H. Farman, Petra Henning, Henrik Ryberg, Marie K Lagerquist, Louise Grahnemo, Antti Koskela, Claes Ohlsson, Ellis R. Levin, Jianyao Wu, Sofia Movérare-Skrtic, Karin Gustafsson
Publikováno v:
The Journal of endocrinology. 239(3)
The importance of estrogen receptor α (ERα) for the regulation of bone mass in males is well established. ERα mediates estrogenic effects both via nuclear and membrane-initiated ERα (mERα) signaling. The role of mERα signaling for the effects o
Autor:
Vikte Lionikaite, Jan-Åke Gustafsson, Hans Carlsten, Claes Ohlsson, Sara H Windahl, Jianyao Wu, Sofia Movérare-Skrtic, Marie K Lagerquist, Ulrika Islander, Klara Sjögren, Helen H. Farman, Karin H Nilsson, Petra Henning, Karin Gustafsson, Annica Andersson
Publikováno v:
The Journal of Endocrinology
Estrogen treatment has positive effects on the skeleton, and we have shown that estrogen receptor alpha (ERα) expression in cells of hematopoietic origin contributes to a normal estrogen treatment response in bone tissue. T lymphocytes are implicate