Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Viktória Koroknai"'
Autor:
István Szász, Tímea Kiss, Attila Mokánszki, Viktória Koroknai, János Deák, Vikas Patel, Krisztina Jámbor, Róza Ádány, Margit Balázs
Publikováno v:
Molecular and Cellular Probes, Vol 67, Iss , Pp 101888- (2023)
Recently, liquid biopsy, as a promising approach was introduced for the analysis of different tumor-derived circulating markers including tumor DNA and cell free DNA (ct/cfDNA). Identification of mutations in cfDNA may allow the early detection of tu
Externí odkaz:
https://doaj.org/article/6456d77d8158409fa1084d18c8d8327a
Publikováno v:
Pathology and Oncology Research, Vol 28 (2022)
Osteopontin (OPN) is a multifunctional glycoprotein that physiologically interacts with different types of integrins. It is considered to be a possible prognostic biomarker in certain tumor types; however, various splicing isoforms exist, which have
Externí odkaz:
https://doaj.org/article/931121900a004cdba0843d210e0bbec1
Autor:
István Szász, Viktória Koroknai, Vikas Patel, Tibor Hajdú, Tímea Kiss, Róza Ádány, Margit Balázs
Publikováno v:
Biomedicines, Vol 9, Iss 2, p 96 (2021)
HA15 is a new anti-melanoma drug that triggers endoplasmic reticulum (ER) stress and causes deleterious effects on melanoma cell viability due to autophagy and apoptosis, regardless of driver mutations or drug resistance. In this study, we investigat
Externí odkaz:
https://doaj.org/article/b9fbfd75fec64e98b018658eb0becfe8
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 10; Pages: 8901
Cytokines and chemokines (chemotactic cytokines) are soluble extracellular proteins that bind to specific receptors and play an integral role in the cell-to-cell signaling network. In addition, they can promote the homing of cancer cells into differe
Cytokines and chemokines (chemotactic cytokines) are soluble extracellular proteins that bind to specific receptors and play an integral role in the cell-to-cell signaling network, in addition can promote the homing of cancer cells into different org
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8ae6558867273cd5c524b9e6b9f25a3
https://doi.org/10.20944/preprints202304.0650.v1
https://doi.org/10.20944/preprints202304.0650.v1
Autor:
Viktória, Koroknai
Publikováno v:
Magyar onkologia. 66(3)
Tumour cell invasion is the first step in metastasis, during which cells are able to infiltrate surrounding tissues. We aimed to investigate genetic and epigenetic differences associated with the invasiveness in melanoma. To determine the invasivenes
Publikováno v:
Cancers; Volume 13; Issue 23; Pages: 6058
Combination treatment using BRAF/MEK inhibitors is a promising therapy for patients with advanced BRAFV600E/K mutant melanoma. However, acquired resistance largely limits the clinical efficacy of this drug combination. Identifying resistance mechanis
Publikováno v:
Cancers, Vol 13, Iss 6058, p 6058 (2021)
Cancers
Cancers
Simple Summary Melanoma is the most aggressive, deadliest form of skin cancer. Combined BRAF-MEK inhibitor (BRAFi/MEKi) therapy was a breakthrough in the treatment of melanoma with BRAFV600-mutations. However, many patients frequently develop drug re
Publikováno v:
Magyar onkologia. 65(2)
Target-specific inhibition of the BRAFV600E mutant protein has been a major breakthrough in the treatment of metastatic cutaneous melanoma. However, the success of therapies is significantly overshadowed by the development of resistance. Understandin
Autor:
Róza Ádány, Szilvia Ecsedi, Tímea Kiss, Laura Vízkeleti, Viktória Koroknai, Margit Balázs, István Szász, Orsolya Papp
Publikováno v:
Melanoma Research. 27:180-188
A large variety of molecular pathways in melanoma progression suggests that no individual molecular alteration is crucial in itself. Our aim was to define the molecular alterations underlying metastasis formation. Gene expression profiling was perfor