Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Viktória Hajzer"'
Autor:
Vladimir Frecer, Július Durmis, E. Varečková, Zuzana Tučeková, Attila Latika, Jakub Kollar, Radovan Šebesta, Stanislav Miertus, Viktória Hajzer, Roman Fisera, F Kostolanský
Publikováno v:
Organic & Biomolecular Chemistry. 15:1828-1841
Oseltamivir is an important antiviral drug, which possess three chirality centers in its structure. From eight possible stereoisomers, only two have been synthesized and evaluated so far. We describe herein the stereoselective synthesis, computationa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09552b816810a80a03ac4279cac05957
https://doi.org/10.1039/c6ob02673g
https://doi.org/10.1039/c6ob02673g
Publikováno v:
Helvetica Chimica Acta. 95:2421-2428
Organocatalytic Michael addition of alkoxyacetaldehyde 1 to N-protected 2-nitroethene-1-amine 2 (Scheme 2) is a key step in the synthesis of an important antiviral agent, oseltamivir. Screening of a large array of structurally diverse acids as potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccea2e23593e97ef445d8a0cde14d2b3
https://doi.org/10.1002/hlca.201200527
https://doi.org/10.1002/hlca.201200527
Autor:
Attila Latika, Martin Huťka, Henrich Brath, Juraj Rehák, Viktória Hajzer, Štefan Toma, Ambroz Almássy, Július Durmis, Radovan Šebesta
Publikováno v:
Synthesis; Vol 44
The organocatalytic addition of substituted oxyacetaldehydes to 2-acylaminonitroethenes proceeded with good to high diastereoselectivities and enantioselectivities. The resulting adducts reacted with ethyl 2-(diethoxyphosphoryl) acrylate to afford hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f81f7530a3c6a8cee31a3ca18669f0b
https://doi.org/10.1055/s-0031-1290396
https://doi.org/10.1055/s-0031-1290396