Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Vikrant Palande"'
Autor:
Ravi K Anchoori, Ssu-Hsueh Tseng, Hua-Ling Tsai, Vikrant Palande, Michelle A Rudek, Richard B S Roden
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0305710 (2024)
There is an urgent unmet need for more targeted and effective treatments for advanced epithelial ovarian cancer (EOC). The emergence of drug resistance is a particular challenge, but small molecule covalent inhibitors have promise for difficult targe
Externí odkaz:
https://doaj.org/article/2db63bf16e0e4c7bacaecfd447382c57
Autor:
Vikrant Palande, Tali Siegal, Rajesh Detroja, Alessandro Gorohovski, Rainer Glass, Charlotte Flueh, Andrew A. Kanner, Yoseph Laviv, Sagi Har‐Nof, Adva Levy‐Barda, Marcela Viviana Karpuj, Marina Kurtz, Shira Perez, Dorith Raviv Shay, Milana Frenkel‐Morgenstern
Publikováno v:
Molecular Oncology, Vol 16, Iss 10, Pp 2098-2114 (2022)
Glioblastoma (GBM) is the most common type of glioma and is uniformly fatal. Currently, tumour heterogeneity and mutation acquisition are major impedances for tailoring personalized therapy. We collected blood and tumour tissue samples from 25 GBM pa
Externí odkaz:
https://doaj.org/article/7404d3c9bebe4cf098a443e9081400b3
Autor:
Jessica M. Costa da Silva, Catarina Torres Pinho, Paulo Pimentel Assumpção, Williams Fernandes Barra, Kelly Cristina da Silva Oliveira, Vikrant Palande, Iago Barroso Ramos, Gregory J. Riggins, Sidney Santos, Milana Frenkel-Morgenstern, Rommel Mario Rodriguez Burbano, Danielle Queiroz Calcagno
Publikováno v:
Molecular Cancer Research. 18:517-528
Circulating tumor DNA (ctDNA) has recently emerged as a minimally invasive “liquid biopsy” tool in precision medicine. ctDNA-genomic DNA fragments that are released into the bloodstream after the active secretion of microvesicles or tumor cell ly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::667209bd9bd791ebbac467e05520b4db
https://doi.org/10.1158/1541-7786.mcr-19-0768
https://doi.org/10.1158/1541-7786.mcr-19-0768
Autor:
Vikrant Palande, Tali Siegal, Rajesh Detroja, Alessandro Gorohovski, Rainer Glass, Charlotte Flueh, Andrew A. Kanner, Yoseph Laviv, Sagi Har‐Nof, Adva Levy‐Barda, Marcela Viviana Karpuj, Marina Kurtz, Shira Perez, Dorith Raviv Shay, Milana Frenkel‐Morgenstern
Publikováno v:
Molecular oncology. 16(10)
Glioblastoma (GBM) is the most common type of glioma and is uniformly fatal. Currently, tumour heterogeneity and mutation acquisition are major impedances for tailoring personalized therapy. We collected blood and tumour tissue samples from 25 GBM pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b97356c3e7fb6d3cc0239d7fa5322cf4
https://pubmed.ncbi.nlm.nih.gov/34875133
https://pubmed.ncbi.nlm.nih.gov/34875133
Publikováno v:
Journal of visualized experiments : JoVE. (163)
Identifying mutations in tumors of cancer patients is a very important step in disease management. These mutations serve as biomarkers for tumor diagnosis as well as for the treatment selection and its response in cancer patients. The current gold st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::185a463f708003736bbde17111595fd3
https://pubmed.ncbi.nlm.nih.gov/32986022
https://pubmed.ncbi.nlm.nih.gov/32986022
Autor:
Marina Kurtz, Vikrant Palande, Milana Frenkel-Morgenstern, Dorith Raviv Shay, Rajesh Detroja, Shira Perez, Alessandro Gorohovski, Rainer Glass, Charlotte Flueh, Tali Siegal
Gliomas account for about 80% of all malignant brain tumours. Diagnosis is achieved by radiographic imaging followed by tumour resection, to determine tumour cell type, grade and molecular characteristics. Glioblastoma multiforme (GBM) is the most co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ff14fc7c491dd9a4a092ce50f08045
https://doi.org/10.1101/2020.02.25.963975
https://doi.org/10.1101/2020.02.25.963975
Autor:
Dorith Raviv-Shay, Alessandro Gorohovski, Deepak Balamurali, Vikrant Palande, Milana Frenkel-Morgenstern, Rajesh Detroja
Publikováno v:
Nucleic Acids Research
Chimeric RNA transcripts are formed when exons from two genes fuse together, often due to chromosomal translocations, transcriptional errors or trans-splicing effect. While these chimeric RNAs produce functional proteins only in certain cases, they p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a7786ce279c0db1b1b01f886727a4a
https://doi.org/10.1093/nar/gkz1025
https://doi.org/10.1093/nar/gkz1025
Autor:
Alexandra Benouaich-Amiel, Marina Kurtz, Shlomit Yust-Katz, Adva Levy-Barda, Charlotte Flueh, Shira Perez, Milana Frenkel-Morgenstern, Rajesh Detroja, Andrew A. Kanner, Alessandro Gorohovski, Sagi Har Nof, Rainer Glass, Dorith Raviv Shay, Tali Siegal, Yoseph Laviv, Vikrant Palande
Publikováno v:
Neuro Oncol
BACKGROUND GBM is characterized by intratumoral heterogeneity. Tumor heterogeneity, clonal diversity and mutation acquisition hamper the ability to tailor personalized therapy for GBM. Tumor sampling has limited ability to accurately capture the mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad3f6b9b4162ef7c1998d7d20a36d0bb
https://doi.org/10.1093/neuonc/noaa215.705
https://doi.org/10.1093/neuonc/noaa215.705
Publikováno v:
ESMO Open. 3:A138-A139
Introduction Gliomas are the most frequent tumours of brain, and they make up about 30% of all brain and central nervous system tumours, and 80% of all malignant brain tumours. Diagnosis of different glioma tumour types and their tumour grade is an e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21a3b851189902b03068d8dbe546b613
https://doi.org/10.1136/esmoopen-2018-eacr25.332
https://doi.org/10.1136/esmoopen-2018-eacr25.332
Autor:
Alessandro Gorohovski, Milana Frenkel-Morgenstern, Somnath Tagore, Assaf Malka, Vikrant Palande, Dorith Raviv-Shay
Publikováno v:
Nucleic Acids Research
Discovery of chimeric RNAs, which are produced by chromosomal translocations as well as the joining of exons from different genes by trans-splicing, has added a new level of complexity to our study and understanding of the transcriptome. The enhanced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b851da072a251ea8a6b5c3f7d4f443e
https://pubmed.ncbi.nlm.nih.gov/27899596
https://pubmed.ncbi.nlm.nih.gov/27899596