Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Vikrant Kumar Sinha"'
Autor:
Yi Zhang, Guojia Xie, Ji-Eun Lee, Mohamad Zandian, Deepthi Sudarshan, Benjamin Estavoyer, Caroline Benz, Tiina Viita, Golareh Asgaritarghi, Catherine Lachance, Clémence Messmer, Leandro Simonetti, Vikrant Kumar Sinha, Jean-Philippe Lambert, Yu-Wen Chen, Shu-Ping Wang, Ylva Ivarsson, El Bachir Affar, Jacques Côté, Kai Ge, Tatiana G. Kutateladze
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The human methyltransferase and transcriptional coactivator MLL4 and its paralog MLL3 are frequently mutated in cancer. MLL4 and MLL3 monomethylate histone H3K4 and contain a set of uncharacterized PHD fingers. Here, we report a novel functi
Externí odkaz:
https://doaj.org/article/638cdaae4793463e86fdbad0e7036a1b
Autor:
Somnath Shee, Reshma T Veetil, Karthikeyan Mohanraj, Mayashree Das, Nitish Malhotra, Devleena Bandopadhyay, Hussain Beig, Shalini Birua, Shreyas Niphadkar, Sathya Narayanan Nagarajan, Vikrant Kumar Sinha, Chandrani Thakur, Raju S Rajmani, Nagasuma Chandra, Sunil Laxman, Mahavir Singh, Areejit Samal, Aswin N Seshasayee, Amit Singh
Publikováno v:
eLife, Vol 12 (2023)
Mycobacterium tuberculosis (Mtb) is evolutionarily equipped to resist exogenous reactive oxygen species (ROS) but shows vulnerability to an increase in endogenous ROS (eROS). Since eROS is an unavoidable consequence of aerobic metabolism, understandi
Externí odkaz:
https://doaj.org/article/3b2cb188fc114b36bd4986382c8f85df
Autor:
Om Prakash Sharma, Yellamandaya Vadlamudi, Arun Gupta Kota, Vikrant Kumar Sinha, Muthuvel Suresh Kumar
Publikováno v:
Journal of Vector Borne Diseases, Vol 50, Iss 3, Pp 155-162 (2013)
This review article discusses the current scenario of the national and international burden due to lymphatic filariasis (LF) and describes the active elimination programmes for LF and their achievements to eradicate this most debilitating disease fro
Externí odkaz:
https://doaj.org/article/210d3703d8854fea95f82998b9cafcef
Autor:
Ulli Rothweiler, Chaithanya Kotyada, Saurabh Chugh, Mahavir Singh, Digvijay Bachhav, Pankaj Vilas Jadhav, Ramandeep Singh, Vikrant Kumar Sinha
Publikováno v:
The Biochemical journal. 477(20)
The toxin–antitoxin (TA) systems are small operon systems that are involved in important physiological processes in bacteria such as stress response and persister cell formation. Escherichia coli HigBA complex belongs to the type II TA systems and
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 36:575-589
Serine protease cleaved-complement component 4 (C4) at sessile loop, which is significant for completion of lectin and classical complement pathways at the time of infections. The co-crystalized structure of C4 with Mannose-binding protein-associated