Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Vikram V. Kulkarni"'
Autor:
Ankita Singh, Awadalkareem Adam, Aditi, Bi-Hung Peng, Xiaoying Yu, Jing Zou, Vikram V. Kulkarni, Peter Kan, Wei Jiang, Pei-Yong Shi, Parimal Samir, Irma Cisneros, Tian Wang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Viral variant is one known risk factor associated with post-acute sequelae of COVID-19 (PASC), yet the pathogenesis is largely unknown. Here, we studied SARS-CoV-2 Delta variant-induced PASC in K18-hACE2 mice. The virus replicated productively, induc
Externí odkaz:
https://doaj.org/article/1086a573751c4191956361de2d95bb29
Autor:
Yongxing Wang, Vikram V Kulkarni, Jezreel Pantaleón García, Miguel M Leiva-Juárez, David L Goldblatt, Fahad Gulraiz, Lisandra Vila Ellis, Jichao Chen, Michael K Longmire, Sri Ramya Donepudi, Philip L Lorenzi, Hao Wang, Lee-Jun Wong, Michael J Tuvim, Scott E Evans
Publikováno v:
PLoS Pathogens, Vol 19, Iss 9, p e1011138 (2023)
Pneumonia is a worldwide threat, making discovery of novel means to combat lower respiratory tract infection an urgent need. Manipulating the lungs' intrinsic host defenses by therapeutic delivery of certain pathogen-associated molecular patterns pro
Externí odkaz:
https://doaj.org/article/b16611b4866742938bff92c35c629d1c
Autor:
David L. Goldblatt, Gabriella Valverde Ha, Shradha Wali, Vikram V. Kulkarni, Michael K. Longmire, Ana M. Jaramillo, Rosha P. Chittuluru, Adrienne Fouts, Margarita Martinez-Moczygemba, Jonathan T. Lei, David P. Huston, Michael J. Tuvim, Burton F. Dickey, Scott E. Evans
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Allergic asthma is a chronic inflammatory respiratory disease associated with eosinophilic infiltration, increased mucus production, airway hyperresponsiveness, and airway remodeling. Epidemiologic data reveal that the prevalence of allergic sensitiz
Externí odkaz:
https://doaj.org/article/dd1b05bdffe9477f901fdf3109e68501
Autor:
Sebastian Wurster, Jezreel Pantaleón García, Nathaniel D Albert, Ying Jiang, Keerthi Bhoda, Vikram V Kulkarni, Yongxing Wang, Thomas J Walsh, Scott Evans, Dimitrios P Kontoyiannis
Publikováno v:
The Journal of Infectious Diseases. 227:901-906
Influenza-associated pulmonary aspergillosis (IAPA) is a feared complication in patients with influenza tracheobronchitis, especially those receiving corticosteroids. Herein, we established a novel IAPA mouse model with low-inoculum Aspergillus infec
Autor:
Carson T. Kirkpatrick, Yongxing Wang, Miguel M. Leiva Juarez, Pooja Shivshankar, Jezreel Pantaleón García, Alexandria K. Plumer, Vikram V. Kulkarni, Hayden H. Ware, Fahad Gulraiz, Miguel A. Chavez Cavasos, Gabriela Martinez Zayas, Shradha Wali, Andrew P. Rice, Hongbing Liu, James M. Tour, William K. A. Sikkema, Ana S. Cruz Solbes, Keith A. Youker, Michael J. Tuvim, Burton F. Dickey, Scott E. Evans
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
Externí odkaz:
https://doaj.org/article/df8541068a8445818a2d6e6013048203
Autor:
Hayden H Ware, Vikram V Kulkarni, Yongxing Wang, Jezreel Pantaleón García, Miguel Leiva Juarez, Carson T Kirkpatrick, Shradha Wali, Sarah Syed, Alexander D Kontoyiannis, William K A Sikkema, James M Tour, Scott E Evans
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0208216 (2019)
Pneumonia remains a global health threat, in part due to expanding categories of susceptible individuals and increasing prevalence of antibiotic resistant pathogens. However, therapeutic stimulation of the lungs' mucosal defenses by inhaled exposure
Externí odkaz:
https://doaj.org/article/42692dc9e85d45079357b6b7efd6f22b
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology.
Autor:
Yongxing Wang, Vikram V. Kulkarni, Jezreel Pantaleón García, Miguel M. Leiva-Juárez, David L. Goldblatt, Fahad Gulraiz, Jichao Chen, Sri Ramya Donepudi, Philip L. Lorenzi, Hao Wang, Lee-Jun Wong, Michael J. Tuvim, Scott E. Evans
Publikováno v:
bioRxiv
Pneumonia is a worldwide threat, making discovery of novel means to combat lower respiratory tract infections an urgent need. We have previously shown that manipulating the lungs’ intrinsic host defenses by therapeutic delivery of a unique dyad of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0816ffd156a236fe88c2d4d0cf296fe8
https://doi.org/10.1101/2023.01.19.524841
https://doi.org/10.1101/2023.01.19.524841
Autor:
Carson T. Kirkpatrick, Yongxing Wang, Miguel M. Leiva Juarez, Pooja Shivshankar, Jezreel Pantaleón García, Alexandria K. Plumer, Vikram V. Kulkarni, Hayden H. Ware, Fahad Gulraiz, Miguel A. Chavez Cavasos, Gabriela Martinez Zayas, Shradha Wali, Andrew P. Rice, Hongbing Liu, James M. Tour, William K. A. Sikkema, Ana S. Cruz Solbes, Keith A. Youker, Michael J. Tuvim, Burton F. Dickey, Scott E. Evans
Publikováno v:
mBio, Vol 9, Iss 3 (2018)
ABSTRACT Viral pneumonias cause profound worldwide morbidity, necessitating novel strategies to prevent and treat these potentially lethal infections. Stimulation of intrinsic lung defenses via inhalation of synergistically acting Toll-like receptor
Externí odkaz:
https://doaj.org/article/bad5b71e30944f789382fafb101c7a34
Autor:
Jezreel Pantaleón García, Vikram V Kulkarni, Tanner C Reese, Shradha Wali, Saima J Wase, Jiexin Zhang, Ratnakar Singh, Mauricio S Caetano, Humam Kadara, Seyed Javad Moghaddam, Faye M Johnson, Jing Wang, Yongxing Wang, Scott E Evans
Publikováno v:
NAR Genomics and Bioinformatics. 4
Bioactive molecule library screening may empirically identify effective combination therapies, but molecular mechanisms underlying favorable drug–drug interactions often remain unclear, precluding further rational design. In the absence of an accep