Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Vikram R. Jayanth"'
Publikováno v:
International Journal of Human Genetics. 7:307-314
The radiomimetic drug bleomycin induced chromosomal aberrations (CA) and micronuclei (MN) were studied in peripheral blood lymphocytes (PBL), as reference to normal cells and Glioma (BMG -1) as reference to tumor cells, with and without exposure to 2
Publikováno v:
International Journal of Human Genetics. 6:133-138
KEYWORDS Bleomycin; Mitomycin-C; chromosomal aberrations; sister chromatid exchanges ABSTRACT The effect of 2-deoxy-D-glucose (2-DG), an antimetabolite of glucose was studied in peripheral blood lymphocytes (PBL) exposed to radiomimetic drug bleomyci
Autor:
V. Vettriselvi, S. Suganya, K. Vijayalakshmi, M. Krishnan, Solomon F. D. Paul, Vikram R. Jayanth
Publikováno v:
International Journal of Immunogenetics. 33:69-72
To determine the genetic diversity of the human leucocyte antigen (HLA)-A*19 group of alleles in the south Indian Tamil population, we studied 100 random healthy unrelated individuals. The frequency of HLA-A*19 was 37% with A*33 (45.9%), A*32 (29.7%)
Autor:
Maddaly Ravi, Vikram R. Jayanth, V. Vettri Selvi, Solomon F. D. Paul, Mahadevan Krishnan, K. Vijayalakshmi
Publikováno v:
International Journal of Human Genetics. 4:51-54
For risk assessment, it is necessary to evaluate the dose of human exposure to mutagens. Previous studies support the somatic mutation theory of carcinogenesis. It is therefore of great importance ...
Autor:
B.Karthikeya Prabhu, Solomon F. D. Paul, Perumal Venkatachalam, K. Muthuvelu, B. Gowri, Vikram R. Jayanth
Publikováno v:
International Journal of Human Genetics. 4:45-49
KEYWORDS 2-DG; dicentrics; radioprotection ABSTRACT The glucose antimetabolite, 2-deoxy-D-glucose (2-DG) has previously been shown to be a radio- sensitiser in certain tumours and a protector in dividing lymphocytes. Since the majority of lymphocytes
Publikováno v:
The Anthropologist. 7:257-259
Lansteiner and Levine described a blood group system in 1927 called the MN system. According to thistheory, three possible genotypes MM, MN and NN occur. The antigenic determinant of human MN syste...
Publikováno v:
Journal of cancer research and therapeutics. 5
Background: Chemotherapy is the treatment of cancer with drugs, often used as either adjuvant or neoadjuvant or in conjunction with radiation and surgery. Unfortunately, majority of the drugs are toxic to normal tissues, the toxicity being resulting
Autor:
Solomon F. D. Paul, V. Vettriselvi, K. Vijayalakshmi, M. Krishnan, Vikram R. Jayanth, Sunil Shroff
Publikováno v:
Cancer biomarkers : section A of Disease markers. 1(4-5)
CYPIA1 activates environmental procarcinogens and catalyzes oxidative metabolism of estrogens and is likely to play an important role in the etiology of prostate cancer. To evaluate this phenomenon, the association between two single nucleotide polym
Autor:
K, Vijayalakshmi, V, Vettriselvi, M, Krishnan, Sunil, Shroff, K N, Vishwanathan, Vikram R, Jayanth, Solomon F D, Paul
Publikováno v:
Asian Pacific journal of cancer prevention : APJCP. 6(3)
Inter-individual differences in cancer susceptibility may be mediated in part through polymorphic variability in the bioactivation and detoxification of carcinogens. The glutathione S-transferases (GSTs), which are active in detoxification of wide va
Publikováno v:
Radiation Research. 143:165
Plateau-phase A549 cells exhibit a high capacity for repair of potentially lethal radiation damage (PLD) when allowed to recover in their own spent medium. Addition of either insulin or insulin-like growth factor-1 (IGF-1) to the spent medium 60 to 1