Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Vikram Natwarsinhji Sisodiya"'
Autor:
Brian M. Zeglis, Outi Keinänen, Kimberly J. Edwards, Vikram Natwarsinhji Sisodiya, Ashwin Ragupathi, Sai Kiran Sharma, Jason S. Lewis, Omar Hamdy, Robert Tchelepi, Charles M. Rudin, John T. Poirier, Jacob Pourat, Joshua A. Korsen, Hetal Sarvaiya, Laura Saunders, Pierre Adumeau
Publikováno v:
Bioconjugate Chemistry
Delta-like ligand 3 (DLL3) is a therapeutic target for the treatment of small cell lung cancer, neuroendocrine prostate cancer, and isocitrate dehydrogenase mutant glioma. In the clinic, DLL3-targeted 89Zr-immunoPET has the potential to aid in the as
Autor:
Julia Gavrilyuk, Amy Laysang, Magda K. Holda, Robert Tchelepi, Zachary Swinney, Christina O. Lee, James W. Purcell, Dong Jun Lee, Marybeth A. Pysz, Samuel A. Williams, Baiwei Lin, Joseph Sandoval, Omar Hamdy, Joseph P. Lyssikatos, Vikram Natwarsinhji Sisodiya, Amanda M. Valdiosera, Hetal Sarvaiya, Monette Aujay, Christine Gu, Dane Holte
Publikováno v:
Bioorganicmedicinal chemistry letters. 30(24)
PNU-159682 is a highly potent secondary metabolite of nemorubicin belonging to the anthracycline class of natural products. Due to its extremely high potency and only partially understood mechanism of action, it was deemed an interesting starting poi
Autor:
Christina E. Lee, Christine Gu, Baiwei Lin, Qifeng Chen, Emmanuel N. Pitsinos, Vikram Natwarsinhji Sisodiya, Joseph Sandoval, Amanda M. Valdiosera, Alexander Schammel, Zhaoyong Lu, Justin Clubb, Kyriacos C. Nicolaou, Nicole Barbour, Julia Gavrilyuk, Monette Aujay, Hetal Sarvaiya, Robert Tchelepi, Ruofan Li
Publikováno v:
Journal of the American Chemical Society. 142(29)
Our previous studies with shishijimicin A resulted in the total synthesis of this scarce marine natural product and a number of its simpler analogues endowed with picomolar potencies against certain cancer cell lines. Herein, we describe the design,
Autor:
Scott J. Dylla, Zhaomei Zhang, Aaron Kempema, Sheila Bheddah, Laura Saunders, Shravanthi Madhavan, Christine Saechao, Sandro Vivona, Alina He, Marybeth Pysz, Monette Aujay, Alex Bankovich, Kimberly Walter, Erik Huntzicker, Xi Zhao, David Liu, Kristyn Hayashi, Julia Gavrilyuk, Vikram Natwarsinhji Sisodiya, Holger Karsunky, Dorothy French, Wolf R. Wiedemeyer, Johannes Hampl
Publikováno v:
Clinical Cancer Research. 25:NT-113
Disclosures: All authors are employees of AbbVie. The design, study conduct, and financial support for this research were provided by AbbVie. AbbVie participated in the interpretation of data, review, and approval of the publication. Ovarian cancer d