Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Vikram G. Panse"'
Autor:
Marta J. Strumillo, Michaela Oplová, Cristina Viéitez, David Ochoa, Mohammed Shahraz, Bede P. Busby, Richelle Sopko, Romain A. Studer, Norbert Perrimon, Vikram G. Panse, Pedro Beltrao
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Protein phosphorylation has various regulatory functions. Here, the authors map 241 phosphorylation hotspot regions across 40 eukaryotic species, showing that they are enriched at interfaces and near catalytic residues, and enable the discovery of fu
Externí odkaz:
https://doaj.org/article/4fa001d5e18b4538b71b32f9cc484470
Autor:
Purnima Klingauf-Nerurkar, Ludovic C Gillet, Daniela Portugal-Calisto, Michaela Oborská-Oplová, Martin Jäger, Olga T Schubert, Agnese Pisano, Cohue Peña, Sanjana Rao, Martin Altvater, Yiming Chang, Ruedi Aebersold, Vikram G Panse
Publikováno v:
eLife, Vol 9 (2020)
Eukaryotic ribosome precursors acquire translation competence in the cytoplasm through stepwise release of bound assembly factors, and proofreading of their functional centers. In case of the pre-60S, these steps include removal of placeholders Rlp24
Externí odkaz:
https://doaj.org/article/b7feb115b93549ec8be75bd76ce9ece0
Publikováno v:
Encyclopedia of Cell Biology ISBN: 9780128216248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4fbbd10c277afa19be24c983dde87ad
https://doi.org/10.1016/b978-0-12-821618-7.00185-1
https://doi.org/10.1016/b978-0-12-821618-7.00185-1
Publikováno v:
eLife, Vol 5 (2016)
Spatial clustering of ribosomal proteins (r-proteins) through tertiary interactions is a striking structural feature of the eukaryotic ribosome. However, the functional importance of these intricate inter-connections, and how they are established is
Externí odkaz:
https://doaj.org/article/c56a425fd3ce4102acdcb854c5e34de7
Autor:
Sabina Schütz, Ute Fischer, Martin Altvater, Purnima Nerurkar, Cohue Peña, Michaela Gerber, Yiming Chang, Stefanie Caesar, Olga T Schubert, Gabriel Schlenstedt, Vikram G Panse
Publikováno v:
eLife, Vol 3 (2014)
Within a single generation time a growing yeast cell imports ∼14 million ribosomal proteins (r-proteins) into the nucleus for ribosome production. After import, it is unclear how these intrinsically unstable and aggregation-prone proteins are targe
Externí odkaz:
https://doaj.org/article/3fc393b43bdf4756972fac031e350d97
Publikováno v:
PLoS Genetics, Vol 8, Iss 8, p e1002915 (2012)
Nuclear export of mRNAs and pre-ribosomal subunits (pre40S and pre60S) is fundamental to all eukaryotes. While genetic approaches in budding yeast have identified bona fide export factors for mRNAs and pre60S subunits, little is known regarding nucle
Externí odkaz:
https://doaj.org/article/712f810014c4420c82330d933245cc46
Autor:
Philippe A Hasgall, David Hoogewijs, Marius B Faza, Vikram G Panse, Roland H Wenger, Gieri Camenisch
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22107 (2011)
The hypoxia-inducible transcription factor (HIF) is a key component of the cellular adaptation mechanisms to hypoxic conditions. HIFα subunits are degraded by prolyl-4-hydroxylase domain (PHD) enzyme-dependent prolyl-4-hydroxylation of LxxLAP motifs
Externí odkaz:
https://doaj.org/article/556484b79578488781c6b64f2eb71a06