Zobrazeno 1 - 10 of 20 pro vyhledávání: '"Vikram Devgan"'
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Akademický článek
p21 as a transcriptional co-repressor of S-phase and mitotic control genes.
Autor: Nuria Ferrándiz, Juan M Caraballo, Lucía García-Gutierrez, Vikram Devgan, Manuel Rodriguez-Paredes, M Carmen Lafita, Gabriel Bretones, Andrea Quintanilla, M Jose Muñoz-Alonso, Rosa Blanco, Jose C Reyes, Neus Agell, M Dolores Delgado, G Paolo Dotto, Javier León
Publikováno v: PLoS ONE, Vol 7, Iss 5, p e37759 (2012)
It has been previously described that p21 functions not only as a CDK inhibitor but also as a transcriptional co-repressor in some systems. To investigate the roles of p21 in transcriptional control, we studied the gene expression changes in two huma
Externí odkaz: https://doaj.org/article/32600aef584b489fad30b84dc5ce7907
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2
Abstract 985: An innovative spatial biology biomarker discovery approach to enable acceleration of drug development
Autor: Jason W. Reeves, Esperanza Anguiano, Vikram Devgan, Nicholas Confuorto, Joachim Schmid, Yan Liang, Joseph Beechem
Publikováno v: Cancer Research. 83:985-985
Biomarker development in the clinical trial setting is frequently limited by the availability of small tissue specimens, such as core needle biopsies. To enable forward and reverse translational assays to best understand patient-specified biomarkers,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2fba55f43fc8e913c0b94feb477d559a
https://doi.org/10.1158/1538-7445.am2023-985
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3
Abstract 6765: Spatial insights into tumor immune evasion illuminated with 1000-plex RNA profiling with CosMx Spatial Molecular Imager
Autor: Claire Williams, Jason W. Reeves, Patrick Danaher, Shanshan He, Sean Kim, Michael Patrick, Julian Preciado, Mark Gregory, Zach Reitz, Justin Jenkins, Rachel Liu, Sarah Murphy, Christine Kang, Byron Hartman, Vikram Devgan, Michael Rhodes, Joseph Beechem
Publikováno v: Cancer Research. 83:6765-6765
Patient response to immunotherapy has been revolutionary but remains limited due to the inability to convert excluded or cold tumors into ones which would be permissive to therapeutic intervention. To treat patients that evade immune therapy, compreh
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8968dcfd795aef89f3902037189a1eb3
https://doi.org/10.1158/1538-7445.am2023-6765
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5
Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKα kinases
Autor: Paola Ostano, Victor A. Neel, Karine Lefort, Daniel Hohl, Anna Mandinova, Ingrid Kolfschoten, Vihren N. Kolev, Jonathan Garlick, G. Paolo Dotto, Valérie Calpini, Wassim Raffoul, Vikram Devgan, Jocelyn Lieb, Giovanna Chiorino
Publikováno v: Genes & Development. 21:562-577
Little is known about the regulation and function of the Notch1 gene in negative control of human tumors. Here we show that Notch1 gene expression and activity are substantially down-modulated in keratinocyte cancer cell lines and tumors, with expres
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d76c647e13cc7bd8b09222e5ceaa6fc2
https://doi.org/10.1101/gad.1484707
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7
p21WAF1/Cip1 Suppresses Keratinocyte Differentiation Independently of the Cell Cycle through Transcriptional Up-regulation of the IGF-I Gene
Autor: Heysun Oh, Vikram Devgan, G. Paolo Dotto, Bach-Cuc Nguyen
Publikováno v: Journal of Biological Chemistry. 281:30463-30470
p21 plays a dual role in keratinocyte growth and differentiation control. It restricts the number of keratinocyte stem cell populations while inhibiting the later stages of differentiation independently of the cell cycle. The molecular/biochemical me
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1604b9b892ccf75cfc1d75a5593393c4
https://doi.org/10.1074/jbc.m604684200
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8
Glucocorticoid-induced Tumor Necrosis Factor Receptor Is a p21 Transcriptional Target Conferring Resistance of Keratinocytes to UV Light-induced Apoptosis
Autor: G. Paolo Dotto, Nita S. Prabhu, Carlo Riccardi, Wafik S. El-Deiry, Jian Wang, Pier Paolo Pandolfi, Marcella Corrado, Vikram Devgan, Caterina Missero
Publikováno v: Journal of Biological Chemistry. 280:37725-37731
Glucocorticoid-induced tumor necrosis factor receptor (GITR) is a member of the tumor necrosis factor receptor superfamily, is expressed in T lymphocytes, and exerts an anti-apoptotic function in these cells. We reported that GITR is also highly expr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a2d28eccc5955187dee0b0b9f119472d
https://doi.org/10.1074/jbc.m507976200
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9
Successful development of viable blastocysts from enhanced green fluorescent protein transgene-microinjected mouse embryos: Comparison of culture media
Autor: Vikram Devgan, Polani B. Seshagiri
Publikováno v: Molecular Reproduction and Development. 65:269-277
To improve efficiency of trans- genesis, we compared M16 and CZB embryo culture media, supporting development to blastocysts of FVB/ N mouse pronuclear-eggs, microinjected with enhanc- ed green fluorescent protein (EGFP) transgene. When EGFP-injected
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0a747a4064c877a727a9425b25ba972
https://doi.org/10.1002/mrd.10306
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10
p21 as a transcriptional co-repressor of S-phase and mitotic control genes
Autor: Juan M. Caraballo, Javier León, José C. Reyes, Lucía García-Gutiérrez, G. Paolo Dotto, M. Dolores Delgado, Rosa M. Blanco, Gabriel Bretones, Neus Agell, M. Carmen Lafita, Manuel Rodríguez-Paredes, M. Jose Muñoz-Alonso, Andrea Quintanilla, Vikram Devgan, Nuria Ferrandiz
Publikováno v: PLoS ONE
Digital.CSIC. Repositorio Institucional del CSIC
instname
Recercat. Dipósit de la Recerca de Catalunya
Dipòsit Digital de la UB
Universidad de Barcelona
PLoS One, vol. 7, no. 5, pp. e37759
PLoS One. 2012;7(5):e37759. Epub 2012 May 25.
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
PLoS ONE, Vol 7, Iss 5, p e37759 (2012)
This is an open-access article distributed under the terms of the Creative Commons Attribution License.-- et al.
It has been previously described that p21 functions not only as a CDK inhibitor but also as a transcriptional co-repressor in some s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54e55a3b58587fc74e08cbfadf1be41d
https://pubmed.ncbi.nlm.nih.gov/22662213
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