Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Vikram Chaudhery"'
Publikováno v:
Sensors, Vol 13, Iss 5, Pp 5561-5584 (2013)
Photonic crystal (PC) surfaces have been demonstrated as a compelling platform for improving the sensitivity of surface-based fluorescent assays used in disease diagnostics and life science research. PCs can be engineered to support optical resonance
Externí odkaz:
https://doaj.org/article/a58ef01c4dc3481fb90a57a5508b0641
Publikováno v:
IEEE Sensors Journal. 12:1272-1279
Photonic crystal enhanced fluorescence (PCEF) has been demonstrated as an effective means for amplifying the excitation provided to surface-bound fluorescent molecules while simultaneously enhancing fluorescence emission collection efficiency. Optima
Autor:
Richard C. Zangar, Sherine George, Meng Lu, Brian T. Cunningham, Ruimin Tan, Cheng-Sheng Huang, Vikram Chaudhery
Publikováno v:
Analytical Chemistry. 83:1425-1430
We report on the use of photonic crystal surfaces as a high-sensitivity platform for detection of a panel of cancer biomarkers in a protein microarray format. The photonic crystal surface is designed to provide an optical resonance at the excitation
Autor:
Sherine George, Hsin-Yu Wu, Pattaramon Vuttipittayamongkol, Lila O. Vodkin, Brian T. Cunningham, Vikram Chaudhery, Sarah Jones, Ian D. Block, Patrick C. Mathias
Publikováno v:
Analytical Chemistry. 82:8551-8557
Technical variability during DNA capture probe printing remains an important obstacle to obtaining high quality data from microarray experiments. While methods that use fluorescent labels for visualizing printed arrays prior to hybridization have bee
Autor:
Ji Sun Choi, Brendan A.C. Harley, James Polans, Yue Zhuo, Vikram Chaudhery, Weili Chen, Meng Lu, Hojeong Yu, Brian T. Cunningham, Kenneth D. Long
Publikováno v:
The Analyst. 138(20)
A form of microscopy that utilizes a photonic crystal biosensor surface as a substrate for cell attachment enables label-free, quantitative, submicron resolution, time-resolved imaging of cell–surface interactions without cytotoxic staining agents
Autor:
Yafang Tan, Brian T. Cunningham, Sherine George, Miki F. Takagi, Vikram Chaudhery, Nabil Amro, Anusha Pokhriyal, Placid M. Ferreira, Meng Lu
Enhancement of the fluorescent output of surface-based fluorescence assays by performing them upon nanostructured photonic crystal (PC) surfaces has been demonstrated to increase signal intensities by >8000×. Using the multiplicative effects of opti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bca8f52e4a7ca3a904104a70ea3a2454
https://europepmc.org/articles/PMC4522268/
https://europepmc.org/articles/PMC4522268/
Publikováno v:
Sensors (Basel, Switzerland)
Sensors, Vol 13, Iss 5, Pp 5561-5584 (2013)
Sensors, Vol 13, Iss 5, Pp 5561-5584 (2013)
Photonic crystal (PC) surfaces have been demonstrated as a compelling platform for improving the sensitivity of surface-based fluorescent assays used in disease diagnostics and life science research. PCs can be engineered to support optical resonance
Publikováno v:
CLEO: 2013.
All fluorescent assays would benefit from greater signal-to-noise ratios (SNRs), which enable detection of disease biomarkers at lower concentrations for earlier disease diagnosis and detection of genes that are expressed at the lowest levels. Here,
Autor:
Brian T. Cunningham, Meng Lu, James Polans, Cheng-Sheng Huang, Richard C. Zangar, Sherine George, Vikram Chaudhery, Anusha Pokhriyal
Publikováno v:
2012 IEEE Sensors.
We report for the first time the combination of a quartz-based photonic crystal (PC) with a detection instrument designed to perform label-free (LF) and enhanced fluorescence (EF) imaging for antibody microarray applications. Label-free detection is
Publikováno v:
Frontiers in Optics 2012/Laser Science XXVIII.
Photonic crystal (PC) surfaces fabricated on silicon substrates provide signal enhancement for surface-bound fluorophores by ~100x using a novel imaging system that illuminates the surface with a laser that matches the conditions for resonant couplin