Zobrazeno 1 - 10
of 888
pro vyhledávání: '"Vikram, Deshpande"'
Autor:
Chan Soo Ha, Desheng Yao, Zhenpeng Xu, Chenang Liu, Han Liu, Daniel Elkins, Matthew Kile, Vikram Deshpande, Zhenyu Kong, Mathieu Bauchy, Xiaoyu (Rayne) Zheng
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Designing and printing metamaterials with customizable architectures enables the realization of unprecedented mechanical behaviors that transcend those of their constituent materials. These behaviors are recorded in the form of response curv
Externí odkaz:
https://doaj.org/article/749c1074f3154b67b4913dc17abaee9f
Autor:
Rebecca L. Porter, Siyu Sun, Micayla N. Flores, Emily Berzolla, Eunae You, Ildiko E. Phillips, Neelima KC, Niyati Desai, Eric C. Tai, Annamaria Szabolcs, Evan R. Lang, Amaya Pankaj, Michael J. Raabe, Vishal Thapar, Katherine H. Xu, Linda T. Nieman, Daniel C. Rabe, David L. Kolin, Elizabeth H. Stover, David Pepin, Shannon L. Stott, Vikram Deshpande, Joyce F. Liu, Alexander Solovyov, Ursula A. Matulonis, Benjamin D. Greenbaum, David T. Ting
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 16 (2022)
Aberrant expression of viral-like repeat elements is a common feature of epithelial cancers, and the substantial diversity of repeat species provides a distinct view of the cancer transcriptome. Repeatome profiling across ovarian, pancreatic, and col
Externí odkaz:
https://doaj.org/article/3ee791906f1046c18bf708762dc93b36
Autor:
Ayo S. Falade, Kerry L. Reynolds, Leyre Zubiri, Vikram Deshpande, Florian J. Fintelmann, Michael Dougan, Meghan J. Mooradian
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Since the first approval of immune checkpoint inhibitors (ICIs) in 2011, these agents have rapidly become an integral treatment option across tumor types. However, with the increased adoption of ICIs, the incidence of immune-related adverse events (i
Externí odkaz:
https://doaj.org/article/d0ff8795a65a4f67827571a1d51912d6
Autor:
Niyati Desai, Azfar Neyaz, Annamaria Szabolcs, Angela R. Shih, Jonathan H. Chen, Vishal Thapar, Linda T. Nieman, Alexander Solovyov, Arnav Mehta, David J. Lieb, Anupriya S. Kulkarni, Christopher Jaicks, Katherine H. Xu, Michael J. Raabe, Christopher J. Pinto, Dejan Juric, Ivan Chebib, Robert B. Colvin, Arthur Y. Kim, Robert Monroe, Sarah E. Warren, Patrick Danaher, Jason W. Reeves, Jingjing Gong, Erroll H. Rueckert, Benjamin D. Greenbaum, Nir Hacohen, Stephen M. Lagana, Miguel N. Rivera, Lynette M. Sholl, James R. Stone, David T. Ting, Vikram Deshpande
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Understanding the pathology in the lungs of patients with COVID-19 might provide clues as to the susceptibility of patients and how the SARS-CoV-2 virus can be fatal. Here the authors analyze cadaveric pulmonary tissue and show one group with high vi
Externí odkaz:
https://doaj.org/article/c26ed9e652d143d4a25413482e8fff81
Autor:
Vikram Deshpande, Alberto Ippolito
Publikováno v:
Acta Biomaterialia. 163:158-169
Contact guidance, the widely-known phenomenon of cell alignment, is an essential step in the organization of adherent cells. This guidance is known to occur by, amongst other things, anisotropic features in the environment including elastic heterogen
Autor:
Daniel Ardeljan, Xuya Wang, Mehrnoosh Oghbaie, Martin S. Taylor, David Husband, Vikram Deshpande, Jared P. Steranka, Mikhail Gorbounov, Wan Rou Yang, Brandon Sie, H. Benjamin Larman, Hua Jiang, Kelly R. Molloy, Ilya Altukhov, Zhi Li, Wilson McKerrow, David Fenyö, Kathleen H. Burns, John LaCava
Publikováno v:
Mobile DNA, Vol 11, Iss 1, Pp 1-19 (2019)
Abstract Background Long interspersed element-1 (LINE-1, L1) is the major driver of mobile DNA activity in modern humans. When expressed, LINE-1 loci produce bicistronic transcripts encoding two proteins essential for retrotransposition, ORF1p and OR
Externí odkaz:
https://doaj.org/article/20049d0c7d7043acb41589f76709b424
Autor:
Michael S. Hughes, Gabriel E. Molina, Steven T. Chen, Hui Zheng, Vikram Deshpande, Riley Fadden, Ryan J. Sullivan, Michael Dougan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-10 (2019)
Abstract Background Immune checkpoint inhibitors (CPIs) are effective against a variety of malignancies but can be limited by inflammatory toxicities such as enterocolitis. Enterocolitis is typically treated with systemically active glucocorticoids.
Externí odkaz:
https://doaj.org/article/319fc9f0a144416db8b5f7b7e5a04fdf
Autor:
Lei Shi, William Shen, Mindy I. Davis, Ke Kong, Phuong Vu, Supriya K. Saha, Ramzi Adil, Johannes Kreuzer, Regina Egan, Tobie D. Lee, Patricia Greninger, Jonathan H. Shrimp, Wei Zhao, Ting-Yu Wei, Mi Zhou, Jason Eccleston, Jonathan Sussman, Ujjawal Manocha, Vajira Weerasekara, Hiroshi Kondo, Vindhya Vijay, Meng-Ju Wu, Sara E. Kearney, Jeffrey Ho, Joseph McClanaghan, Ellen Murchie, Giovanna S. Crowther, Samarjit Patnaik, Matthew B. Boxer, Min Shen, David T. Ting, William Y. Kim, Ben Z. Stanger, Vikram Deshpande, Cristina R. Ferrone, Cyril H. Benes, Wilhelm Haas, Matthew D. Hall, Nabeel Bardeesy
Publikováno v:
Nature Cancer. 4:365-381
Publikováno v:
Journal of Clinical Pathology. 76:285-290
The mouse double minute 2 (MDM2) gene is located on the long arm of chromosome 12 and is the primary negative regulator of p53. TheMDM2gene encodes an E3 ubiquitin–protein ligase that mediates the ubiquitination of p53, leading to its degradation.
Autor:
Sjoerd P. F. T. Nota, Ahmad Al-Sukaini, Shalin S. Patel, Francesco Sabbatino, G. Petur Nielsen, Vikram Deshpande, Jennifer H. Yearley, Soldano Ferrone, Xinhui Wang, Joseph H. Schwab
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
PurposeThe aim of this study was to characterize chondrosarcoma tumor infiltration by immune cells and the expression of immunologically relevant molecules. This information may contribute to our understanding of the role of immunological events in t
Externí odkaz:
https://doaj.org/article/51a12882044449668b7d1f66ff93ac3a