Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Vikki Spaulding"'
Autor:
Jessica D. Weaver, Edward C. Stack, Joshua A. Buggé, Changyun Hu, Lara McGrath, Amy Mueller, Masie Wong, Boris Klebanov, Tanzila Rahman, Rosemary Kaufman, Christine Fregeau, Vikki Spaulding, Michelle Priess, Kristen Legendre, Sarah Jaffe, Dhruvkumar Upadhyay, Anirudh Singh, Chang-Ai Xu, Kristin Krukenberg, Yan Zhang, Yassine Ezzyat, Dorothée Saddier Axe, Michelle R. Kuhne, Michael A. Meehl, Donald R. Shaffer, Brian M. Weist, Dmitri Wiederschain, Fabien Depis, Monica Gostissa
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
The presence of T regulatory (Treg) cells in the tumor microenvironment is associated with poor prognosis and resistance to therapies aimed at reactivating anti-tumor immune responses. Therefore, depletion of tumor-infiltrating Tregs is a potential a
Externí odkaz:
https://doaj.org/article/9a4049560acc4a71971464efbe2cc5d2
Autor:
Edward Stack, Jeff Smith, Yasmin Hashambhoy-Ramsay, Vikki Spaulding, Michelle Priess, Kristin O’Malley, Monica Gostissa, Margaret Willer, Ben Umiker, Donald Shaffer
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/945c3ea2eb844800ad50a8f0bfc39d5e
Autor:
Ben Umiker, Yasmin Hashambhoy-Ramsay, Jeff Smith, Tanzila Rahman, Amy Mueller, Rachel Davidson, Christina Meyer, Gayatri Patankar, Mohammad Murshid Alam, Sarah Jaffe, Kristin Krukenberg, Allison Goodman, Vikki Spaulding, Michelle Priess, Abha Dhaneshwar, Masie Wong, Alexa Diiorio, Kristin O'Malley, Lara McGrath, Margaret Willer, Lauren Pepper, Monica Gostissa, Katalin Kis-Toth, Dmitri Wiederschain, Heather Cohen, Donald R. Shaffer
Publikováno v:
Molecular Cancer Therapeutics. 22:471-484
Tumor-associated macrophages (TAM) play an important role in maintaining the immunosuppressive state of the tumor microenvironment (TME). High levels of CD163+ TAMs specifically are associated with poor prognosis in many solid tumor types. Targeting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdc9ed87146b6d569a16703ed901dc0f
https://doi.org/10.1158/1535-7163.mct-22-0351
https://doi.org/10.1158/1535-7163.mct-22-0351
Autor:
Donald R. Shaffer, Heather Cohen, Dmitri Wiederschain, Katalin Kis-Toth, Monica Gostissa, Lauren Pepper, Margaret Willer, Lara McGrath, Kristin O'Malley, Alexa Diiorio, Masie Wong, Abha Dhaneshwar, Michelle Priess, Vikki Spaulding, Allison Goodman, Kristin Krukenberg, Sarah Jaffe, Mohammad Murshid Alam, Gayatri Patankar, Christina Meyer, Rachel Davidson, Amy Mueller, Tanzila Rahman, Jeff Smith, Yasmin Hashambhoy-Ramsay, Ben Umiker
Sensitivity of LILRB2 as a predictive biomarker for pharmacodynamic response as measured by the macrophage polarization score in histoculture explant cultures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7300803b6c2959ff55929ff818f38977
https://doi.org/10.1158/1535-7163.22551994.v1
https://doi.org/10.1158/1535-7163.22551994.v1
Autor:
Donald R. Shaffer, Heather Cohen, Dmitri Wiederschain, Katalin Kis-Toth, Monica Gostissa, Lauren Pepper, Margaret Willer, Lara McGrath, Kristin O'Malley, Alexa Diiorio, Masie Wong, Abha Dhaneshwar, Michelle Priess, Vikki Spaulding, Allison Goodman, Kristin Krukenberg, Sarah Jaffe, Mohammad Murshid Alam, Gayatri Patankar, Christina Meyer, Rachel Davidson, Amy Mueller, Tanzila Rahman, Jeff Smith, Yasmin Hashambhoy-Ramsay, Ben Umiker
Tumor-associated macrophages (TAM) play an important role in maintaining the immunosuppressive state of the tumor microenvironment (TME). High levels of CD163+ TAMs specifically are associated with poor prognosis in many solid tumor types. Targeting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e89f1a6392cc21d33474e1853be7817
https://doi.org/10.1158/1535-7163.c.6534805.v1
https://doi.org/10.1158/1535-7163.c.6534805.v1
Autor:
Heather Condurso, Amy Mueller, Jessica Jimenez, Lauren Badalucco, Kelly Aldridge, Pauline Sarraf, Michelle Priess, Vikki Spaulding, Sarah Jaffe, Prashanna Balaji Venkatasubramanian, Alexa Diiorio, Geneva Young, Kameron Mori, Karl Wetterhorn, Jeffrey Smith, Morgan Thompson, Jean-Christophe Pignon, Changyun Hu, Brandon Chin, Briana Murphy, Matthew Southard, Katalin Kis-Toth, Monica Gostissa, Dmitri Wiederschain, Andre da Cunha
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e44b0e1a789e48e274bee7127209e37
https://doi.org/10.1136/jitc-2022-sitc2022.0483
https://doi.org/10.1136/jitc-2022-sitc2022.0483
Autor:
Jeffrey Smith, Amy Mueller, Vikki Spaulding, Michelle Priess, Krithi Bala, Andrew Dunn, Sarah Jaffe, Morgan Thompson, Jean-Christophe Pignon, Alexa Diiorio, Andre Cunha, Heather Condurso, Kristin O’Malley, Olivia Petrillo, Prashanna Balaji Venkatasubramanian, Geneva Young, Christina Meyer, Michael Meehl, Katalin Kis-Toth, Monica Gostissa, Dmitri Wiederschain, Ben Umiker, Yasmin Hashambhoy-Ramsay
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::505698af8389532225c27d5331c45b5e
https://doi.org/10.1136/jitc-2022-sitc2022.0945
https://doi.org/10.1136/jitc-2022-sitc2022.0945
Autor:
Donald R. Shaffer, Vikki Spaulding, Edward C. Stack, Kristin Shanea O'malley, Jeffrey W. Smith, Ben Umiker, Margaret Willer, Michelle Priess, Monica Gostissa, Yasmin Hashambhoy-Ramsay
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Leukocyte immunoglobulin-like receptor B2 (LILRB2; ILT4) is an immunoinhibitory protein expressed on the surface of myeloid cells that has been increasingly recognized as a therapeutic target of interest in immuno-oncology (IO). Upon bindi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc704ce7e919eef0c6929caeaabe8d18
https://doi.org/10.1136/jitc-2020-sitc2020.0217
https://doi.org/10.1136/jitc-2020-sitc2020.0217
Autor:
Donald R. Shaffer, Seema Naheed, Chang-Ai Xu, Michael A. Meehl, Jessica Weaver, Monica Gostissa, Edward C. Stack, Joshua Adam Buggé, Masie Wong, Yan Zhang, Vikki Spaulding, Margaret Willer, Alessandro Mora, Anirudh Singh, Kristan Meetze, Lara McGrath, Boris Klebanov, Christine Fregeau, Fabien Dépis, Dhruvkumar Upadhyay, Michelle Priess, Changyun Hu, Ben Umiker, Kristin Legendre
Publikováno v:
Cancer Research. 80:4532-4532
Introduction: Immune checkpoint blockade (ICB) has revolutionized the treatment of many cancers, still most patients do not respond to PD-1 or CTLA-4 inhibitors. Thus, new Immuno-Oncology (IO) therapies that could potentially benefit non-responding p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14b5213193fab5060f3cc3592ee811dd
https://doi.org/10.1158/1538-7445.am2020-4532
https://doi.org/10.1158/1538-7445.am2020-4532
Autor:
Heather Cohen, Yasmin Hashambhoy-Ramsay, Lauren R. Pepper, Jeffrey Y. Smith, Margaret Willer, Kevin Guay, Vikki Spaulding, Kristin O'Malley, Monica Gostissa, Abha Dhaneshwar, Edward C. Stack, Alessandro Mora, Donald R. Shaffer
Publikováno v:
Cancer Research. 79:5007-5007
Introduction: Jounce has generated cell type-specific gene signatures as a means of probing The Cancer Genome Atlas and other large datasets to identify targets that may be important immune checkpoints. Using a tumor-associated macrophage (TAM) gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ccbe3b27f281d422e0a63310bc835c0
https://doi.org/10.1158/1538-7445.am2019-5007
https://doi.org/10.1158/1538-7445.am2019-5007