Intertwined and Finely Balanced: Endoplasmic Reticulum Morphology, Dynamics, Function, and Diseases

Autor: Hannah T. Perkins, Viki Allan

Publikováno v: Cells, Vol 10, Iss 9, p 2341 (2021)

The endoplasmic reticulum (ER) is an organelle that is responsible for many essential subcellular processes. Interconnected narrow tubules at the periphery and thicker sheet-like regions in the perinuclear region are linked to the nuclear envelope. I

Externí odkaz: https://doaj.org/article/072434300cd54bdd9b5d5a01b4d6d6a0

Protein Localization by Fluorescence Microscopy : A Practical Approach

Autor: Viki Allan

There is an ever-increasing number of genes that have been sequenced but are of completely unknown function. The ability to determine the location of such gene products within the cell, either by the use of antibodies or by the production of chimeras

Local Analysis of Heterogeneous Intracellular Transport: Slow and Fast moving Endosomes

Autor: Daniel Han, Alessandro Taloni, Thomas A. Waigh, Gianni Pagnini, Nickolay Korabel, Sergei Fedotov, Viki Allan

Publikováno v: Entropy
Entropy, Vol 23, Iss 958, p 958 (2021)
Volume 23
Issue 8
Korabel, N, Han, D, Taloni, A, Pagnini, G, Fedotov, S, Allan, V & Waigh, T A 2021, ' Local Analysis of Heterogeneous Intracellular Transport: Slow and Fast Moving Endosomes ', Entropy, vol. 23, no. 8, 958 . https://doi.org/10.3390/e23080958
Entropy (Basel, Online) 23 (2021): 958-1–958-15. doi:10.3390/e23080958
info:cnr-pdr/source/autori:Korabel N.; Han D.; Taloni A.; Pagnini G.; Fedotov S.; Allan V.; Waigh T.A./titolo:Local analysis of heterogeneous intracellular transport: Slow and fast moving endosomes/doi:10.3390%2Fe23080958/rivista:Entropy (Basel, Online)/anno:2021/pagina_da:958-1/pagina_a:958-15/intervallo_pagine:958-1–958-15/volume:23

Trajectories of endosomes inside living eukaryotic cells are highly heterogeneous in space and time and diffuse anomalously due to a combination of viscoelasticity, caging, aggregation and active transport. Some of the trajectories display switching

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cc3e68c3f7c32c807696c7849d36036
http://arxiv.org/abs/2107.11553

Efa6 protects axons and regulates their growth and branching by inhibiting microtubule polymerisation at the cortex

Autor: Viki Allan, Alex Rathbone, Meredith Lees, Pilar Okenve-Ramos, André Voelzmann, Jill Parkin, Yue Qu, Claire T. Friel, Andreas Prokop, Natalia Sanchez-Soriano, Karel Dorey, Ines Hahn

Publikováno v: eLife, Vol 8 (2019)
eLife
Qu, Y, Hahn, I, Lees, M, Parkin, J, Voelzmann, A, Dorey, K, Rathbone, A, Friel, C, Allan, V, Okenve Ramos, P, Sanchez-Soriano, N & Prokop, A 2019, ' Efa6 protects axons and regulates their growth and branching by inhibiting microtubule polymerisation at the cortex ', eLife, vol. 8, e50319 . https://doi.org/10.7554/eLife.50319

Cortical collapse factors affect microtubule (MT) dynamics at the plasma membrane. They play important roles in neurons, as suggested by inhibition of axon growth and regeneration through the Arf activator Efa6 inC. elegans, and by neurodevelopmental

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc1855d5db85c9fbbdd0837d468e6fcc
https://elifesciences.org/articles/50319

Molecular motors and the Golgi complex: Staying put and moving through

Autor: Kim Brownhill, Laura Wood, Viki Allan

Publikováno v: Seminars in Cell & Developmental Biology. 20:784-792

The Golgi apparatus is a highly dynamic organelle through which nascent proteins released from the endoplasmic reticulum (ER) are trafficked. Proteins are post-translationally modified within the Golgi and subsequently packaged into carriers for tran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b4de3e2913b623cda111b2812c52b74
https://doi.org/10.1016/j.semcdb.2009.03.019