Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Vikas A. Gupta"'
Autor:
Sara A. Scott, Ellen M. Marin, Kathryn T. Maples, Nisha S. Joseph, Craig C. Hofmeister, Vikas A. Gupta, Madhav V. Dhodapkar, Jonathan L. Kaufman, Sagar Lonial, Ajay K. Nooka
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/7ea3beeed4234ced9c029a3f7555c48e
Autor:
M. Hope Robinson, Nancy Y. Villa, David L. Jaye, Ajay K. Nooka, Alyssa Duffy, Samuel S. McCachren, Julia Manalo, Jeffrey M. Switchenko, Sierra Barnes, Sayalee Potdar, Maryam I. Azeem, Ava A. Horvat, Vaunita C. Parihar, Jingjing Gong, Yan Liang, Geoffrey H. Smith, Vikas A. Gupta, Lawrence H. Boise, Jonathan L. Kaufman, Craig C. Hofmeister, Nisha S. Joseph, Sagar Lonial, Kavita M. Dhodapkar, Madhav V. Dhodapkar
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 15 (2023)
Entry of antigen-specific T cells into human tumors is critical for immunotherapy, but the underlying mechanisms are poorly understood. Here, we combined high-dimensional spatial analyses with in vitro and in vivo modeling to study the mechanisms und
Externí odkaz:
https://doaj.org/article/4e93c2e8320c4a29894d2dbcaa88a70f
Autor:
Vikas A. Gupta, Shannon M. Matulis, Benjamin G. Barwick, R. Devin Bog, Conrad W. Shebelut, Mala Shanmugam, Paola Neri, Nizar J. Bahlis, Madhav V. Dhodapkar, Leonard T. Heffner, Craig C. Hofmeister, Nisha S. Joseph, Sagar Lonial, Jonathan L. Kaufman, David L. Jaye, Ajay K. Nooka, Lawrence H. Boise
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 8, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/b80806186ba7462e812a4322e8cf5287
Autor:
Remya Nair, Vimal Subramaniam, Benjamin G. Barwick, Vikas A. Gupta, Shannon M. Matulis, Sagar Lonial, Lawrence H. Boise, Ajay K. Nooka, Kuzhali Muthumalaiappan, Mala Shanmugam
Publikováno v:
Haematologica, Vol 107, Iss 9 (2022)
Externí odkaz:
https://doaj.org/article/e555d024adbd48c9975863d16d1d2407
Autor:
Jayeeta Ghose, Ada Dona, Mariam Murtadha, Emine Gulsen Gunes, Enrico Caserta, Ji Young Yoo, Luke Russell, Alena Cristina Jaime-Ramirez, Benjamin G. Barwick, Vikas A. Gupta, James F. Sanchez, Douglas W. Sborov, Steven T. Rosen, Amrita Krishnan, Lawrence H. Boise, Balveen Kaur, Craig C. Hofmeister, Flavia Pichiorri
Publikováno v:
Molecular Therapy: Oncolytics, Vol 20, Iss , Pp 519-531 (2021)
Because most patients with multiple myeloma (MM) develop resistance to current regimens, novel approaches are needed. Genetically modified, replication-competent oncolytic viruses exhibit high tropism for tumor cells regardless of cancer stage and pr
Externí odkaz:
https://doaj.org/article/65d17a0839584df484a779e3dc1740bf
Autor:
Richa Bajpai, Aditi Sharma, Abhinav Achreja, Claudia L. Edgar, Changyong Wei, Arusha A. Siddiqa, Vikas A. Gupta, Shannon M. Matulis, Samuel K. McBrayer, Anjali Mittal, Manali Rupji, Benjamin G. Barwick, Sagar Lonial, Ajay K. Nooka, Lawrence H. Boise, Deepak Nagrath, Mala Shanmugam
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Venetoclax monotherapy is effective in 40% of t(11:14) positive multiple myeloma (MM). Here, the authors show that electron transport chain complex I (CI) and complex II (CII) activity predict MM sensitivity to venetoclax, and inhibition of CI with I
Externí odkaz:
https://doaj.org/article/ab542c51a366402d8b83cd98c687f243
Autor:
Benjamin G. Barwick, Paola Neri, Nizar J. Bahlis, Ajay K. Nooka, Madhav V. Dhodapkar, David L. Jaye, Craig C. Hofmeister, Jonathan L. Kaufman, Vikas A. Gupta, Daniel Auclair, Jonathan J. Keats, Sagar Lonial, Paula M. Vertino, Lawrence H. Boise
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Multiple myeloma is frequently characterised by translocation of genes next to the immunoglobulin heavy chain locus. In this study, the authors sequence a large cohort of high risk myeloma samples and find translocations of cMyc to the immunoglobulin
Externí odkaz:
https://doaj.org/article/f7edb1aa7e034097bfaeab285876053f
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
B cell activation and differentiation yields plasma cells with high affinity antibodies to a given antigen in a time-frame that allows for host protection. Although the end product is most commonly humoral immunity, the rapid proliferation and somati
Externí odkaz:
https://doaj.org/article/880c386be0494892a9e824317a16aea3
Autor:
Ricardo de Matos Simoes, Ryosuke Shirasaki, Sondra L. Downey-Kopyscinski, Geoffrey M. Matthews, Benjamin G. Barwick, Vikas A. Gupta, Daphné Dupéré-Richer, Shizuka Yamano, Yiguo Hu, Michal Sheffer, Eugen Dhimolea, Olga Dashevsky, Sara Gandolfi, Kazuya Ishiguro, Robin M. Meyers, Jordan G. Bryan, Neekesh V. Dharia, Paul J. Hengeveld, Johanna B. Brüggenthies, Huihui Tang, Andrew J. Aguirre, Quinlan L. Sievers, Benjamin L. Ebert, Brian J. Glassner, Christopher J. Ott, James E. Bradner, Nicholas P. Kwiatkowski, Daniel Auclair, Joan Levy, Jonathan J. Keats, Richard W. J. Groen, Nathanael S. Gray, Aedin C. Culhane, James M. McFarland, Joshua M. Dempster, Jonathan D. Licht, Lawrence H. Boise, William C. Hahn, Francisca Vazquez, Aviad Tsherniak, Constantine S. Mitsiades
Publikováno v:
de Matos Simoes, R, Shirasaki, R, Downey-Kopyscinski, S L, Matthews, G M, Barwick, B G, Gupta, V A, Dupéré-Richer, D, Yamano, S, Hu, Y, Sheffer, M, Dhimolea, E, Dashevsky, O, Gandolfi, S, Ishiguro, K, Meyers, R M, Bryan, J G, Dharia, N V, Hengeveld, P J, Brüggenthies, J B, Tang, H, Aguirre, A J, Sievers, Q L, Ebert, B L, Glassner, B J, Ott, C J, Bradner, J E, Kwiatkowski, N P, Auclair, D, Levy, J, Keats, J J, Groen, R W J, Gray, N S, Culhane, A C, McFarland, J M, Dempster, J M, Licht, J D, Boise, L H, Hahn, W C, Vazquez, F, Tsherniak, A & Mitsiades, C S 2023, ' Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias ', Nature Cancer, vol. 4, no. 5, pp. 754-773 . https://doi.org/10.1038/s43018-023-00550-x
Nature Cancer, 4(5), 754-773. Nature Research
Nature Cancer, 4(5), 754-773. Nature Research
Clinical progress in multiple myeloma (MM), an incurable plasma cell (PC) neoplasia, has been driven by therapies that have limited applications beyond MM/PC neoplasias and do not target specific oncogenic mutations in MM. Instead, these agents targe
Autor:
Marinda Scrushy, Melissa Thornton, Audrey Stevens, Raghav Chandra, Alana Carrasco, Kayla Philip, Vikas S Gupta, Mitri Khoury, Jacqueline Babb, Rohit Sharma, Kareem R. Abdelfattah, Herbert Zeh, Ryan P. Dumas
Publikováno v:
Journal of Surgical Education. 80:726-730