Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Vikaas S Sohal"'
Autor:
Ruchi Malik, Emily Ling-Lin Pai, Anna N Rubin, April M Stafford, Kartik Angara, Petros Minasi, John L. Rubenstein, Vikaas S Sohal, Daniel Vogt
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Although cortical GABAergic interneuron (CIN) dysfunction is implicated in several neuropsychiatric disorders, we still know very little about how they attain their unique properties or how their dysfunction impacts neuropsychiatric disorders. In thi
Externí odkaz:
https://doaj.org/article/80b4682b9d2d4e25bfb4a1bda0b1e7cc
Publikováno v:
PLoS Biology, Vol 19, Iss 5, p e3001235 (2021)
New technologies make it possible to measure activity from many neurons simultaneously. One approach is to analyze simultaneously recorded neurons individually, then group together neurons which increase their activity during similar behaviors into a
Externí odkaz:
https://doaj.org/article/25e253f7cb8a4faaa660564988debe5c
Autor:
Jonathan Garst-Orozco, Ruchi Malik, Thomas A Lanz, Mark L Weber, Hualin Xi, Dominique Arion, John F Enwright, David A Lewis, Patricio O'Donnell, Vikaas S Sohal, Derek L Buhl
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0233895 (2020)
Deficits in fast-spiking inhibitory interneurons (FSINs) within the dorsolateral prefrontal cortex (dlPFC) are hypothesized to underlie cognitive impairment associated with schizophrenia. Though representing a minority of interneurons, this key cell
Externí odkaz:
https://doaj.org/article/db1f708a89e44baf864091e2ba0bd6cd
Publikováno v:
eLife, Vol 7 (2018)
The synchronous activity of groups of neurons is increasingly thought to be important in cortical information processing and transmission. However, most studies of processing in the primary auditory cortex (AI) have viewed neurons as independent filt
Externí odkaz:
https://doaj.org/article/83c6d8d79d5e4efaa0193dcf1688a996
Publikováno v:
eLife, Vol 6 (2017)
The medial prefrontal cortex plays a key role in higher order cognitive functions like decision making and social cognition. These complex behaviors emerge from the coordinated firing of prefrontal neurons. Fast-spiking interneurons (FSIs) control th
Externí odkaz:
https://doaj.org/article/99818abc55c549698a0b9e7dd6d01fb3
Publikováno v:
Cells, Vol 13, Iss 1, p 52 (2023)
The mammalian target of rapamycin (mTOR) signaling pathway is a powerful regulator of cell proliferation, growth, synapse maintenance and cell fate. While intensely studied for its role in cancer, the role of mTOR signaling is just beginning to be un
Externí odkaz:
https://doaj.org/article/87376a05024d4b78891e1950a02b9768
Publikováno v:
Nature
Nature, 2023, 617, pp.548-554. ⟨10.1038/s41586-023-06012-9⟩
Nature, vol 617, iss 7961
Nature, 2023, 617, pp.548-554. ⟨10.1038/s41586-023-06012-9⟩
Nature, vol 617, iss 7961
Changes in patterns of activity within the medial prefrontal cortex enable rodents, non-human primates and humans to update their behaviour to adapt to changes in the environment—for example, during cognitive tasks1–5. Parvalbumin-expressing inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f991f9848943ffc8a22188646e5c30
https://doi.org/10.1038/s41586-023-06012-9
https://doi.org/10.1038/s41586-023-06012-9
Autor:
Denise E. Allen, Kevin C. Donohue, Cathryn R. Cadwell, David Shin, Matthew G. Keefe, Vikaas S. Sohal, Tomasz J. Nowakowski
Publikováno v:
Science (New York, N.Y.), vol 376, iss 6600
Science
Science
Progenitors of the developing human neocortex reside in the ventricular and outer subventricular zones (VZ and OSVZ, respectively). However, whether cells derived from these niches have similar developmental fates is unknown. By performing fate mappi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05b7735d329ab8f75dcde7fd3e70de16
https://doi.org/10.1126/science.abm5224
https://doi.org/10.1126/science.abm5224
Publikováno v:
J Neurosci
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 42, iss 27
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 42, iss 27
Traumatic brain injury (TBI) is a leading cause of neurologic disability; the most common deficits affect prefrontal cortex-dependent functions such as attention, working memory, social behavior, and mental flexibility. Despite this prevalence, littl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c59f24538b4e865f8e0fe8b7cb14fe74
https://doi.org/10.1523/jneurosci.0097-22.2022
https://doi.org/10.1523/jneurosci.0097-22.2022
Emotional responses arise from limbic circuits including the hippocampus and amygdala. In the human brain, beta-frequency communication between these structures correlates with self-reported mood and anxiety. However, both the mechanism and significa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db68241175da9c6f7a4787f681c83c8c
https://doi.org/10.1101/2022.11.11.516218
https://doi.org/10.1101/2022.11.11.516218
