Zobrazeno 1 - 10 of 159 pro vyhledávání: '"Vijverberg, H.P.M."'
1
Organic solvent-induced changes in membrane geometry in human SH-SY5Y neuroblastoma cells - a common narcotic effect?
Autor: Meulenberg, C.J.W., de Groot, A., Westerink, R.H.S., Vijverberg, H.P.M., Sub IRAS Tox CMT/NTX, LS IRAS Tox Algemeen, dIRAS RA-1
Publikováno v: NeuroToxicology, 55, 74. Elsevier bedrijfsinformatie b.v.
Exposure to organic solvents may cause narcotic effects. At the cellular level, these narcotic effects have been associated with a reduction in neuronal excitability caused by changes in membrane structure and function. In order to critically test wh
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfbcb095a3c32e72215b593e1ebc7a76
https://dspace.library.uu.nl/handle/1874/346727
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2
Sense in Pb2+ sensing
Autor: Vijverberg, H.P.M., Westerink, R.H.S.
It is generally acknowledged that Pb(2+), which is sequestered by live cells from their direct environment, affects a large number of cellular processes at picomolar to micromolar concentrations. However, resolving the specific molecular targets and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______101::0114145aa3aa2d428b999760de1e90f7
https://dspace.library.uu.nl/handle/1874/340800
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3
Selective inhibition of human heteromeric α9α10 nicotinic acetylcholine receptors at a low agonist concentration by low concentrations of ototoxic organic solvents
Autor: van Kleef, Gina, Vijverberg, H.P.M., Westerink, R.H.S.
Ethylbenzene and para-xylene (p-xylene), but not the chemically closely related organic solvents ortho-xylene (o-xylene) and meta-xylene (m-xylene), are known to cause ototoxicity and irreversible hearing loss, though the underlying mechanisms are st
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______101::e3971cdaca1b4a5b7504f933f680ee4b
https://dspace.library.uu.nl/handle/1874/259629
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4
Selective inhibition of human heteromeric alpha9alpha10 nicotinic acetylcholine receptors at a low agonist concentration by low concentrations of ototoxic organic solvents
Autor: van Kleef, Gina, Vijverberg, H.P.M., Westerink, R.H.S., Risk Assessment of Toxic and Immunomodulatory Agents, Sub IRAS Tox CMT/NTX, Dep IRAS
Publikováno v: Toxicology in Vitro, 22(6), 1568. NLM (Medline)
Ethylbenzene and para-xylene (p-xylene), but not the chemically closely related organic solvents ortho-xylene (o-xylene) and meta-xylene (m-xylene), are known to cause ototoxicity and irreversible hearing loss, though the underlying mechanisms are st
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::534c81e12aecf7de6cb55d9fe19456d2
https://pubmed.ncbi.nlm.nih.gov/18602458
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5
Hydroxylation increases the neurotoxic potential of BDE-47 to affect exocytosis and calcium homeostasis in PC12 cells
Autor: Dingemans, M.M.L., de Groot, A., van Kleef, R.G., Bergman, A., van den Berg, M., Vijverberg, H.P.M., Westerink, R.H.S.
BACKGROUND: Oxidative metabolism, resulting in the formation of hydroxylated polybrominated diphenyl ether (PBDE) metabolites, may enhance the neurotoxic potential of brominated flame retardants. OBJECTIVE: Our objective was to investigate the effect
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______101::9177efcd4a2bc410e83f4988266ff912
https://dspace.library.uu.nl/handle/1874/259626
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