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Decapping factor Dcp2 controls mRNA abundance and translation to adjust metabolism and filamentation to nutrient availability.

Autor: Vijjamarri, Anil Kumar, Niu, Xiao, Vandermeulen, Matthew D., Onu, Chisom, Zhang, Fan, Qiu, Hongfang, Gupta, Neha, Gaikwad, Swati, Greenberg, Miriam L., Cullen, Paul J., Lin, Zhenguo, Hinnebusch, Alan G.

Publikováno v: eLife; 6/22/2023, p1-42, 42p

Mycobacterium tuberculosis virulence-regulator PhoP interacts with alternative sigma factor SigE during acid-stress response

Autor: Roohi Bansal, Ritesh Rajesh Sevalkar, Vijjamarri Anil Kumar, Dibyendu Sarkar, Prabhat Ranjan Singh

Publikováno v: Molecular Microbiology. 104:400-411

The ability to sense acid stress and mount an appropriate adaptive response by Mycobacterium tuberculosis, which adapts a long-term residence in the macrophage phagosome, remains one of the critical features that defines mycobacterial physiology and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f83f80b7fbd29a7e481b81b9ae420ef0
https://doi.org/10.1111/mmi.13635

Unique N-terminal Arm of Mycobacterium tuberculosis PhoP Protein Plays an Unusual Role in Its Regulatory Function

Autor: Dibyendu Sarkar, Ritesh Rajesh Sevalkar, Vijjamarri Anil Kumar, Arijit Kumar Das, Roohi Bansal

Publikováno v: Journal of Biological Chemistry. 288:29182-29192

Mycobacterium tuberculosis PhoP, a master regulator involved in complex lipid biosynthesis and expression of unknown virulence determinants, is composed of an N-terminal receiver domain and a C-terminal effector domain. The two experimentally charact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1029ad4170686cb059f56c83bac6032c
https://doi.org/10.1074/jbc.m113.499905

Decapping activators Edc3 and Scd6 act redundantly with Dhh1 in post-transcriptional repression of starvation-induced pathways.

Autor: Kumar R; Division of Molecular and Cellular Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD., Zhang F; Division of Molecular and Cellular Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD., Niphadkar S; Institute for Stem Cell Science and Regenerative Medicine (DBT-inStem) GKVK Post Bellary Road Bangalore 560065., Onu C; Department of Biological Sciences, Wayne State University, Detroit, MI., Vijjamarri AK; Division of Molecular and Cellular Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD., Greenberg ML; Department of Biological Sciences, Wayne State University, Detroit, MI., Laxman S; Institute for Stem Cell Science and Regenerative Medicine (DBT-inStem) GKVK Post Bellary Road Bangalore 560065., Hinnebusch AG; Division of Molecular and Cellular Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Aug 28. Date of Electronic Publication: 2024 Aug 28.