Population Pharmacokinetics and Pharmacodynamics of Paclitaxel and Carboplatin in Ovarian Cancer Patients: A Study by the European Organization for Research and Treatment of Cancer-Pharmacology and Molecular Mechanisms Group and New Drug Development Group

Autor: Joerger, M., Huitema, A. D. R., Richel, D. J., Dittrich, C., Pavlidis, Nicholas, Briassoulis, E. Ch, Vermorken, J. B., Strocchi, E., Martoni, A., Sorio, R., Sleeboom, H. P., Izquierdo, M. A., Jodrell, D. I., Calvert, H., Boddy, A. V., Hollema, H., Féty, R., Vijgh, W. J. F. Van Der, Hempel, G., Chatelut, E., Karlsson, M., Wilkins, J., Tranchand, B., Schrijvers, A. H. G. J., Twelves, C., Beijnen, J. H., Schellens, J. H. M.

Publikováno v: Clinical Cancer Research, 13(21), 6410-6418. AMER ASSOC CANCER RESEARCH
Clinical cancer research, 13(21), 6410-6418. American Association for Cancer Research Inc.
Clinical Cancer Research
Clinical cancer research

Purpose: Paclitaxel and carboplatin are frequently used in advanced ovarian cancer following cytoreductive surgery. Threshold models have been used to predict paclitaxel pharmacokinetic-pharmacodynamics, whereas the time above paclitaxel plasma conce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f35d45e907084e44cb16cab0bcb5b9df
https://doi.org/10.1158/1078-0432.ccr-07-0064

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Publikováno v: Physiological Measurement; Nov1998, Vol. 19 Issue 4, p1-1, 1p