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Population Pharmacokinetics and Pharmacodynamics of Paclitaxel and Carboplatin in Ovarian Cancer Patients: A Study by the European Organization for Research and Treatment of Cancer-Pharmacology and Molecular Mechanisms Group and New Drug Development Group

Autor: Joerger, M., Huitema, A. D. R., Richel, D. J., Dittrich, C., Pavlidis, Nicholas, Briassoulis, E. Ch, Vermorken, J. B., Strocchi, E., Martoni, A., Sorio, R., Sleeboom, H. P., Izquierdo, M. A., Jodrell, D. I., Calvert, H., Boddy, A. V., Hollema, H., Féty, R., Vijgh, W. J. F. Van Der, Hempel, G., Chatelut, E., Karlsson, M., Wilkins, J., Tranchand, B., Schrijvers, A. H. G. J., Twelves, C., Beijnen, J. H., Schellens, J. H. M.

Publikováno v: Clinical Cancer Research, 13(21), 6410-6418. AMER ASSOC CANCER RESEARCH
Clinical cancer research, 13(21), 6410-6418. American Association for Cancer Research Inc.
Clinical Cancer Research
Clinical cancer research

Purpose: Paclitaxel and carboplatin are frequently used in advanced ovarian cancer following cytoreductive surgery. Threshold models have been used to predict paclitaxel pharmacokinetic-pharmacodynamics, whereas the time above paclitaxel plasma conce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f35d45e907084e44cb16cab0bcb5b9df
https://doi.org/10.1158/1078-0432.ccr-07-0064

In vitro screening of antitumour agents for cardiotoxicity by means of isolated mouse left atria

Autor: Acker, F. A. A., Acker, S. A. B. E., Haenen, G. R. M. M., Aalt Bast, Vijgh, W. J. F.

Publikováno v: Anticancer Research, 20(6B), 4483-4487. International Institute of Anticancer Research
Scopus-Elsevier
Maastricht University

Cardiotoxicity, a side-effect that can occur after treatment with an anticancer drug, has severe clinical implications Therefore, a model is desired to screen new anticancer dugs ol drug combinations for possible cardiotoxic side-effects. In the pres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e287e0caef2ea03d164b5b2892b45847
https://cris.maastrichtuniversity.nl/en/publications/b98b55ed-7b86-4876-a26e-f390d0b6a4d3

Bepridil in combination with anthracyclines in the attempt to reverse anthracycline-resistance in cancer patients

Autor: van Kalken, C.K., van der Hoeven, J.J.M., de Jong, J., Giaccone, G., Schuurhuis, G.J., Maessen, P.A., Blokhuis, W.M.D., van der Vijgh, W., Pinedo, H.M.

Publikováno v: van Kalken, C K, van der Hoeven, J J M, de Jong, J, Giaccone, G, Schuurhuis, G J, Maessen, P A, Blokhuis, W M D, van der Vijgh, W & Pinedo, H M 1991, ' Bepridil in combination with anthracyclines in the attempt to reverse anthracycline-resistance in cancer patients ', European Journal of Cancer, vol. 27, no. 6, pp. 739-744 .
European Journal of Cancer, 27(6), 739-744. Pergamon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4dd59a1640afb776c30eb2cc65c03b52
https://research.vumc.nl/ws/files/9071680/8410

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