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of 9
pro vyhledávání: '"Vijaykumar Sayeli"'
Autor:
Jagan Nadipelly, Vijaykumar Sayeli, Parimala Kadhirvelu, Jaikumar Shanmugasundaram, Binoy Varghese Cheriyan, Viswanathan Subramanian
Publikováno v:
Integrative Medicine Research, Vol 7, Iss 2, Pp 159-167 (2018)
Background: The anti - nociceptive effect of 7, 2′, 3′ – trimethoxy flavone, 7, 2′, 4′ – trimethoxy flavone, 7, 3′, 4′ – trimethoxy flavone and 7, 5, 4′ – trimethoxy flavone against inflammatory, neurogenic and thermal pain in m
Externí odkaz:
https://doaj.org/article/d67b78f1f9be4bb58e3842cd0042c5a8
Autor:
Binoy Varghese Cheriyan, Vijaykumar Sayeli, Jagan Nadipelly, Parimala Kathirvelu, Viswanathan Subramanian, Jaikumar Shanmugasundaram
Publikováno v:
European Neuropsychopharmacology. 36:100-110
Anxiety disorders are common worldwide and novel compounds are investigated for anxiolytic effect. A few studies have demonstrated the anxiolytic-like activity of natural and synthetic flavonoids. 5-methoxyflavone, a synthetic flavone derivative, has
Autor:
Binoy Varghese Cheriyan, Jagan Nadipelly, Viswanathan Subramanian, Jaikumar Shanmugasundaram, Vijaykumar Sayeli, Parimala Kadhirvelu
Publikováno v:
Inflammopharmacology. 27:1155-1167
Previous reports suggest flavonoids as potent analgesic compounds. Based on these observations, the present study investigated the antinociceptive action of flavonol, 3′, 4′-dimethoxy flavonol, 6, 3′-dimethoxy flavonol, 7, 2′-dimethoxy flavon
Autor:
Jaikumar Shanmugasundaram, Jagan Nadipelly, Vijaykumar Sayeli, Binoy Varghese Cheriyan, Viswanathan Subramanian, Parimala Kathirvelu
Publikováno v:
Biomedicine & Pharmacotherapy. 108:85-94
Flavonoids have been shown to possess central nervous system (CNS) depressant effect mediated through the ionotropic GABAA receptors. In the present study, 5-methoxyflavone was evaluated for sedative-hypnotic like activity in mice and the mechanisms
Autor:
Vijaykumar Sayeli, Viswanathan Subramanian, Binoy Varghese Cheriyan, Jagan Nadipelly, Parimala Kathirvelu, Jaikumar Shanmugasundaram
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 15, Iss 1, Pp FC01-FC06 (2021)
Introduction: Therapy with anticancer drugs like paclitaxel, platinum complexes and vincristine result in severe peripheral neuropathy. Very few treatment options are available to overcome this debilitating side effect. Flavone and its monohydroxy de
Effect of flavonol and its dimethoxy derivatives on paclitaxel-induced peripheral neuropathy in mice
Autor:
Binoy Varghese Cheriyan, Viswanathan Subramanian, Vijaykumar Sayeli, Jagan Nadipelly, Jaikumar Shanmugasundaram, Parimala Kadhirvelu
Publikováno v:
Journal of Basic and Clinical Physiology and Pharmacology. 29:525-535
Background: Peripheral neuropathy is the dose limiting side effect of many anticancer drugs. Flavonoids exhibit good antinociceptive effect in animal models. Their efficacy against different types of nociception has been documented. The present study
Autor:
Binoy Varghese, Cheriyan, Parimala, Kadhirvelu, Jagan, Nadipelly, Jaikumar, Shanmugasundaram, Vijaykumar, Sayeli, Viswanathan, Subramanian
Publikováno v:
Pharmacognosy Magazine
Aim: To evaluate the anti-nociceptive activity of 7-methoxy coumarin isolated from ethyl acetate fraction of the alcoholic extract of Eupatorium triplinerve Vahl. Materials and Methods: The shade dried leaves of E. triplinerve were extracted with eth
Publikováno v:
International Journal of Basic & Clinical Pharmacology. 8:1577
Background: The present study was carried out to evaluate the antipyretic activity of alcoholic extract of Murraya koenigii leaves in rabbits by using PGE1 induced hyperpyrexia method. We found that not much work has been done on the antipyretic effe
Autor:
Viswanathan Subramanian, Vijaykumar Sayeli, Jagan Nadipelly, Binoy Varghese Cheriyan, Parimala Kadhirvelu, Jaikumar Shanmugasundaram
Publikováno v:
Journal of Basic and Clinical Physiology and Pharmacology. 27
Background The present study was designed to investigate the anti-nociceptive activity of a few structurally related trimethoxy flavones (7,2',3'-TMF, 7,2',4'-TMF, 7,3',4'-TMF and 7,5,4'-TMF) and the possible mechanisms involved. Methods Anti-nocicep