A Novel Combinatorial Regimen Using Sorafenib and Uttroside B, A US FDA-designated 'Orphan Drug', for the Treatment of Hepatocellular Carcinoma.

Autor: Keerthana CK; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, 695014, Kerala, India.; Department of Biotechnology, University of Kerala, Thiruvananthapuram, 695011, Kerala, India., Aiswarya SU; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, 695014, Kerala, India., Rayginia TP; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, 695014, Kerala, India.; Department of Biotechnology, University of Kerala, Thiruvananthapuram, 695011, Kerala, India., Vijayan Y; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, 695014, Kerala, India., James S; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, 695014, Kerala, India., Shifana SC; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, 695014, Kerala, India.; Molecular Bioassay Laboratory, Institute of Advanced Virology, Thonnakkal, Thiruvananthapuram, 695317, Kerala, India., Sundaram S; Department of Pathology, Government Medical College, Kottayam 686008, Kerala, India., Induja DK; Chemical Sciences and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram 695019, Kerala, India., Lankalapalli RS; Chemical Sciences and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram 695019, Kerala, India., Harikumar KB; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, 695014, Kerala, India., Anto RJ; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, 695014, Kerala, India.; Molecular Bioassay Laboratory, Institute of Advanced Virology, Thonnakkal, Thiruvananthapuram, 695317, Kerala, India.

Publikováno v: Anti-cancer agents in medicinal chemistry [Anticancer Agents Med Chem] 2024; Vol. 24 (19), pp. 1431-1441.

Cardamonin Attenuates Experimental Colitis and Associated Colorectal Cancer.

Autor: James S; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (RGCB), Thiruvananthapuram 695014, India., Aparna JS; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (RGCB), Thiruvananthapuram 695014, India., Babu A; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (RGCB), Thiruvananthapuram 695014, India., Paul AM; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (RGCB), Thiruvananthapuram 695014, India.; Manipal Academy of Higher education (MAHE), Manipal 576104, India., Lankadasari MB; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (RGCB), Thiruvananthapuram 695014, India., Athira SR; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (RGCB), Thiruvananthapuram 695014, India., Kumar SS; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (RGCB), Thiruvananthapuram 695014, India., Vijayan Y; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (RGCB), Thiruvananthapuram 695014, India.; Manipal Academy of Higher education (MAHE), Manipal 576104, India., Namitha NN; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (RGCB), Thiruvananthapuram 695014, India., Mohammed S; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (RGCB), Thiruvananthapuram 695014, India., Reshmi G; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (RGCB), Thiruvananthapuram 695014, India., Harikumar KB; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology (RGCB), Thiruvananthapuram 695014, India.

Publikováno v: Biomolecules [Biomolecules] 2021 Apr 29; Vol. 11 (5). Date of Electronic Publication: 2021 Apr 29.

The Drug Transporter P-Glycoprotein and Its Impact on Ceramide Metabolism—An Unconventional Ally in Cancer Treatment.

Autor: Ung, Johnson¹ (AUTHOR) ju7a@virginia.edu, Kassai, Miki² (AUTHOR) kassaim18@ecu.edu, Tan, Su-Fern^3,4 (AUTHOR) st4ub@virginia.edu, Loughran Jr., Thomas P.^3,4 (AUTHOR) djf2g@virginia.edu, Feith, David J.^3,4 (AUTHOR), Cabot, Myles C.² (AUTHOR) cabotm@ecu.edu

Publikováno v: International Journal of Molecular Sciences. Sep2024, Vol. 25 Issue 18, p9825. 24p.

The Induction of G2/M Phase Cell Cycle Arrest and Apoptosis by the Chalcone Derivative 1C in Sensitive and Resistant Ovarian Cancer Cells Is Associated with ROS Generation.

Autor: Salanci, Šimon¹ (AUTHOR) simon.salanci@student.upjs.sk, Vilková, Mária² (AUTHOR) maria.vilkova@upjs.sk, Martinez, Lola³ (AUTHOR) lmartinez@cnio.es, Mirossay, Ladislav¹ (AUTHOR) ladislav.mirossay@upjs.sk, Michalková, Radka¹ (AUTHOR) radka.michalkova@upjs.sk, Mojžiš, Ján¹ (AUTHOR) jan.mojzis@upjs.sk

Publikováno v: International Journal of Molecular Sciences. Jul2024, Vol. 25 Issue 14, p7541. 26p.

Integrated single-cell sequencing and transcriptome sequencing to reveal a 9-gene prognostic signature of immune cells in colorectal cancer.

Autor: TANG Nan¹, HUANG Huixia^2,3,4, LIU Xiaojian¹ liuxiaojian3000@hotmail.com

Publikováno v: China Oncology. 2024, Vol. 34 Issue 6, p548-560. 13p.