Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Vijayalaxmi C Nalavadi"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Dendritic growth and branching are highly regulated processes and are essential for establishing proper neuronal connectivity. There is a critical phase of early dendrite development when these are heavily regulated by external cues such as trophic f
Externí odkaz:
https://doaj.org/article/58f4516e2d75413fa3619f08da1ebd54
Autor:
Shobha Anilkumar, Jessica A. Hurt, Tsuyoshi Udagawa, Joel D. Richter, Sumantra Chattarji, Mira Jakovcevski, Gary J. Bassell, Juan Marcos Alarcon, Hanoch Kaphzan, Natalie G. Farny, Lori J. Lorenz, Eric Klann, Kentaro Nagaoka, Schahram Akbarian, Maria Ivshina, Vijayalaxmi C Nalavadi
Publikováno v:
Nature medicine
Fragile X syndrome (FXS), the most common cause of inherited mental retardation and autism, is caused by transcriptional silencing of FMR1, which encodes the translational repressor fragile X mental retardation protein (FMRP). FMRP and cytoplasmic po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a446adcd5352496ed4869f8ea2957ce0
https://doi.org/10.1038/nm.3353
https://doi.org/10.1038/nm.3353
Autor:
Andrew M. Swanson, Gary J. Bassell, Laura E Griffin, Phillip Picard-Fraser, Toru Takumi, Vijayalaxmi C Nalavadi
Publikováno v:
The Journal of Neuroscience. 32:15133-15141
Directed transport of the mRNA binding protein, zipcode binding protein1 (ZBP1), into developing axons is believed to play an important role in mRNA localization and local protein synthesis. The role of molecular motors in this process is unclear. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a67715f8bfb4e5c5fadb5fcb2d7fcea5
https://doi.org/10.1523/jneurosci.2006-12.2012
https://doi.org/10.1523/jneurosci.2006-12.2012
Autor:
Gary J. Bassell, Sharon A. Swanger, Vijayalaxmi C Nalavadi, Joel D. Richter, Lori J. Lorenz, Koichi Takeuchi, R. Suzanne Zukin, Jihae Shin, Jong Heon Kim, Tsuyoshi Udagawa
Publikováno v:
Molecular Cell. 47:253-266
Translational control of mRNAs in dendrites is essential for certain forms of synaptic plasticity and learning and memory. CPEB is an RNA-binding protein that regulates local translation in dendrites. Here, we identify poly(A) polymerase Gld2, deaden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73eba379fd140ec3f13fb2e57b88d9e1
https://doi.org/10.1016/j.molcel.2012.05.016
https://doi.org/10.1016/j.molcel.2012.05.016
Autor:
Ravi S. Muddashetty, Christina Gross, Xiaodi Yao, Stephen T. Warren, Vijayalaxmi C Nalavadi, Gary J. Bassell, Lei Xing, Oskar Laur
Publikováno v:
Molecular Cell. 42(5):673-688
The molecular mechanism for how RISC and microRNAs selectively and reversibly regulate mRNA translation in response to receptor signaling is unknown but could provide a means for temporal and spatial control of translation. Here we show that miR-125a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8efe31ebc0bbf5d252c8d6345748e5fd
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(8)
Fragile X syndrome is caused by the loss of fragile X mental retardation protein (FMRP), which represses and reversibly regulates the translation of a subset of mRNAs in dendrites. Protein synthesis can be rapidly stimulated by mGluR-induced and prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d95213d68f3b52909a11ff808752640
https://pubmed.ncbi.nlm.nih.gov/22357842
https://pubmed.ncbi.nlm.nih.gov/22357842
Autor:
Stephanie Ceman, Stephen T. Warren, George Thomas, Usha Narayanan, Vijayalaxmi C Nalavadi, Gary J. Bassell, Mika Nakamoto
Fragile X syndrome is a common form of cognitive deficit caused by the functional absence of fragile X mental retardation protein (FMRP), a dendritic RNA-binding protein that represses translation of specific messages. Although FMRP is phosphorylated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e2b9bde17229f1d4b991b81a9a18e2b
https://europepmc.org/articles/PMC2441545/
https://europepmc.org/articles/PMC2441545/
Autor:
Usha Narayanan, Vijayalaxmi C Nalavadi, David C. Pallas, Gary J. Bassell, Mika Nakamoto, Stephen T. Warren, Stephanie Ceman
Fragile X syndrome is a common form of inherited mental retardation and is caused by loss of fragile X mental retardation protein (FMRP), a selective RNA-binding protein that influences the translation of target messages. Here, we identify protein ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39854026c1e38fe0ddd51c178a2239d3
https://europepmc.org/articles/PMC6673448/
https://europepmc.org/articles/PMC6673448/
Autor:
Vijayalaxmi C Nalavadi, Stephen T. Warren, Michael P. Epstein, Mika Nakamoto, Gary J. Bassell, Usha Narayanan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 104(39)
Fragile X syndrome (FXS), a common inherited form of mental retardation, is caused by the functional absence of the fragile X mental retardation protein (FMRP), an RNA-binding protein that regulates the translation of specific mRNAs at synapses. Alte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dae74eafb510fc418a5cf1f643a3139
https://pubmed.ncbi.nlm.nih.gov/17881561
https://pubmed.ncbi.nlm.nih.gov/17881561
Autor:
Martin Bähler, Michael A. Geeves, Nancy Adamek, Miklós Nyitrai, Vijayalaxmi C Nalavadi, Cristina Bertolini
Myosin IXb (Myo9b) was reported to be a single-headed, processive myosin. In its head domain it contains an N-terminal extension and a large loop 2 insertion that are specific for class IX myosins. We characterized the kinetic properties of purified,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea1a53efb4d6fcea665ce2b42cc1ea6d
http://hdl.handle.net/11562/392677
http://hdl.handle.net/11562/392677