Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Vijayakumar, Velu"'
Autor:
Sivaprakasam T. Selvavinayagam, Sathish Sankar, Yean K. Yong, Amudhan Murugesan, Suvaiyarasan Suvaithenamudhan, Kannan Hemashree, Manivannan Rajeshkumar, Anandhazhvar Kumaresan, Ramendra P. Pandey, Saravanan Shanmugam, Parthiban Arthydevi, Masilamani Senthil Kumar, Natarajan Gopalan, Meganathan Kannan, Narayanaiah Cheedarla, Hong Y. Tan, Ying Zhang, Marie Larsson, Pachamuthu Balakrishnan, Vijayakumar Velu, Siddappa N. Byrareddy, Esaki M. Shankar, Sivadoss Raju
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract In December 2023, we observed a notable shift in the COVID-19 landscape, when JN.1 omicron emerged as the predominant SARS-CoV-2 variant with a 95% incidence. We characterized the clinical profile, and genetic changes in JN.1, an emerging SA
Externí odkaz:
https://doaj.org/article/23fe151c72304f3d83a3333918cd8137
Autor:
Sakthivel Govindaraj, Staple Tyree, Gina Bailey Herring, Sadia J. Rahman, Hemalatha Babu, Chris Ibegbu, Marisa R. Young, C. Christina Mehta, Lisa B. Haddad, Alicia K. Smith, Vijayakumar Velu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundOvarian hormones are known to modulate the immune system in the female genital tract (FGT). We sought to define the impact of the menstrual cycle on the mucosal HIV target cell levels, and tissue-resident CD4 T cells.Materials and methodsHe
Externí odkaz:
https://doaj.org/article/819dfe5fa9e64eeaaec9c839e81fb4d1
Autor:
Venkata S. Bollimpelli, Pradeep B. J Reddy, Sailaja Gangadhara, Tysheena P. Charles, Samantha L. Burton, Gregory K. Tharp, Tiffany M. Styles, Celia C. Labranche, Justin C. Smith, Amit A. Upadhyay, Anusmita Sahoo, Traci Legere, Ayalnesh Shiferaw, Vijayakumar Velu, Tianwei Yu, Mark Tomai, John Vasilakos, Sudhir P. Kasturi, George M. Shaw, David Montefiori, Steven E. Bosinger, Pamela A. Kozlowski, Bali Pulendran, Cynthia A. Derdeyn, Eric Hunter, Rama R. Amara
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Route of immunization can markedly influence the quality of immune response. Here, we show that intradermal (ID) but not intramuscular (IM) modified vaccinia Ankara (MVA) vaccinations provide protection from acquisition of intravaginal tier2
Externí odkaz:
https://doaj.org/article/101d7faa095245b791894f88734b70d5
Autor:
Jaisheela Vimali, Yean K. Yong, Amudhan Murugesan, Hong Y. Tan, Ying Zhang, Rajeev Ashwin, Sivadoss Raju, Pachamuthu Balakrishnan, Marie Larsson, Vijayakumar Velu, Esaki M. Shankar
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 3, p 128 (2024)
Background: Chronic viral infection results in impaired immune responses rendering viral persistence. Here, we compared the quality of T-cell responses among chronic hepatitis B virus (HBV), hepatitis C virus (HCV) and human immunodeficiency virus (H
Externí odkaz:
https://doaj.org/article/2f98be5fc91a4c09ba99fc0f5d0205c0
Autor:
Lisa B. Haddad, Gina Bailey Herring, C. Christina Mehta, Tyree Staple, Marisa R. Young, Sakthivel Govindaraj, Vijayakumar Velu, Alicia K. Smith
Publikováno v:
BMC Women's Health, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Gonadal hormones can modify immune function, which may impact susceptibility to infectious diseases, including Human Immunodeficiency Virus (HIV). There is limited knowledge about how hormonal contraceptives (HC) influence the imm
Externí odkaz:
https://doaj.org/article/4c5cb313ae0545899a87d0e814b7ab75
Autor:
Sakthivel Govindaraj, Narayanaiah Cheedarla, Suneethamma Cheedarla, LesShon S. Irby, Andrew S. Neish, John D. Roback, Alicia K. Smith, Vijayakumar Velu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionMaternally derived antibodies are crucial for neonatal immunity. Understanding the binding and cross-neutralization capacity of maternal and cord antibody responses to SARS-CoV-2 variants following COVID-19 vaccination in pregnancy can in
Externí odkaz:
https://doaj.org/article/cec2ae6ee19c45099d22fd061d17c7cc
Autor:
Sakthivel Govindaraj, Hemalatha Babu, Sunil Kannanganat, Monica Vaccari, Constantinos Petrovas, Vijayakumar Velu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/83b775a9fe944e5a8c9a5dd74ddacae6
Autor:
Sivaprakasam T Selvavinayagam, Bijulal Aswathy, Yean K Yong, Asha Frederick, Lakshmi Murali, Vasudevan Kalaivani, Sree J Karishma, Manivannan Rajeshkumar, Adukkadukkam Anusree, Meganathan Kannan, Natarajan Gopalan, Ramachandran Vignesh, Amudhan Murugesan, Hong Yien Tan, Ying Zhang, Samudi Chandramathi, Munusamy Ponnan Sivasankaran, Pachamuthu Balakrishnan, Sakthivel Govindaraj, Siddappa N Byrareddy, Vijayakumar Velu, Marie Larsson, Esaki M Shankar, Sivadoss Raju
Publikováno v:
PLOS Global Public Health, Vol 3, Iss 11, p e0002327 (2023)
Early detection of latent tuberculosis infection (LTBI) is critical to TB elimination in the current WHO vision of End Tuberculosis Strategy. The study investigates whether detecting plasma cytokines could aid in diagnosing LTBI across household cont
Externí odkaz:
https://doaj.org/article/a51334833c1f4179908ad29c718e7171
Autor:
Jaisheela Vimali, Yean Kong Yong, Amudhan Murugesan, Kumaran Vishnupriya, Rajeev Ashwin, Evangeline Ann Daniel, Pachamuthu Balakrishnan, Sivadoss Raju, Mohamed Rosmawati, Vijayakumar Velu, Marie Larsson, Esaki M. Shankar
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Chronic viral infections represent a leading cause of global morbidity and mortality. Chronic HBV, HCV, and HIV infections result in cytokine perturbations that may hold key implications in understanding the complex disease mechanisms driving virus p
Externí odkaz:
https://doaj.org/article/97a05a0b71984f8d945536ec5481acf4
Autor:
Tiffany M. Styles, Sailaja Gangadhara, Pradeep B. J. Reddy, Anusmita Sahoo, Ayalensh Shiferaw, Sarah Welbourn, Pamela A. Kozlowski, Cynthia A. Derdeyn, Vijayakumar Velu, Rama Rao Amara
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Stabilized HIV envelope (Env) trimeric protein immunogens have been shown to induce strong autologous neutralizing antibody response. However, there is limited data on the immunogenicity and efficacy of stabilized Env expressed by a viral vector-base
Externí odkaz:
https://doaj.org/article/81f9a87b6bff43e3a8a1399b0ad63c82