Zobrazeno 1 - 10
of 58
pro vyhledávání: '"VijayaKumar Sukumaran"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/48f58dc40ab04d66b0cadbe7910348b4
Autor:
Vijayakumar Sukumaran, Hirotsugu Tsuchimochi, Takashi Sonobe, Mark T. Waddingham, Mikiyasu Shirai, James T. Pearson
Publikováno v:
Cardiovascular Diabetology, Vol 19, Iss 1, Pp 1-16 (2020)
Abstract Background Obesity, hypertension and prediabetes contribute greatly to coronary artery disease, heart failure and vascular events, and are the leading cause of mortality and morbidity in developed societies. Salt sensitivity exacerbates endo
Externí odkaz:
https://doaj.org/article/9ba970a0e7c64c4fbc20a76b36f501d3
Autor:
Abdella M. Habib, Karim Nagi, Nagendra Babu Thillaiappan, VijayaKumar Sukumaran, Saghir Akhtar
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
About 50 million of the U.S. adult population suffer from chronic pain. It is a complex disease in its own right for which currently available analgesics have been deemed woefully inadequate since ~20% of the sufferers derive no benefit. Vitamin D, k
Externí odkaz:
https://doaj.org/article/ab850913bfad4e79be3ec002a2f54823
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 6703 (2021)
The SARS-CoV-2 virus utilizes angiotensin converting enzyme (ACE-2) for cell entry and infection. This enzyme has important functions in the renin-angiotensin aldosterone system to preserve cardiovascular function. In addition to the heart, it is exp
Externí odkaz:
https://doaj.org/article/1ee0fb9e061043cc8b2e132c7759a0bb
Autor:
James T Pearson, Mikiyasu Shirai, Vijayakumar Sukumaran, Cheng-Kun Du, Hirotsugu Tsuchimochi, Takashi Sonobe, Mark T Waddingham, Rajesh Katare, Daryl O Schwenke
Publikováno v:
Vascular Biology, Vol 1, Iss 1, Pp H97-H102 (2019)
Ghrelin is a small peptide with important roles in the regulation of appetite, gut motility, glucose homeostasis as well as cardiovascular protection. This review highlights the role that acyl ghrelin plays in maintaining normal endothelial function
Externí odkaz:
https://doaj.org/article/5a0dbb4f12df4203bf8e2a9d84c7af1a
Autor:
Vijayakumar Sukumaran, Hirotsugu Tsuchimochi, Yutaka Fujii, Hiroshi Hosoda, Kenji Kangawa, Tsuyoshi Akiyama, Mikiyasu Shirai, Eisuke Tatsumi, James T. Pearson
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Cardiopulmonary bypass (CPB) induced systemic inflammation significantly contributes to the development of postoperative complications, including respiratory failure, myocardial, renal and neurological dysfunction and ultimately can lead to failure o
Externí odkaz:
https://doaj.org/article/74b030406fcd428a9b3022e016bed60d
Publikováno v:
International Journal of Biological Sciences, Vol 7, Iss 2, Pp 154-167 (2011)
Studies have demonstrated that angiotensin II has been involved in immune and inflammatory responses which might contribute to the pathogenesis of immune-mediated diseases. Recent evidence suggests that oxidative stress may play a role in myocarditis
Externí odkaz:
https://doaj.org/article/4da683f0a16c4bd0867bdcd30018a346
Publikováno v:
International Journal of Biological Sciences, Vol 7, Iss 8, Pp 1077-1092 (2011)
Angiotensin-converting enzyme-2 (ACE-2) is a homolog of ACE that preferentially forms angiotensin-(ANG)-1-7 from angiotensin II (ANG II). We investigated the cardioprotective effects of telmisartan, a well-known angiotensin receptor blockers (ARBs) a
Externí odkaz:
https://doaj.org/article/f6d7150a0cfd4d89b072414e8ab2ecbb
Autor:
Vijayakumar Sukumaran, Onur Mutlu, Mohammad Murtaza, Rawia Alhalbouni, Benjamin Dubansky, Huseyin C Yalcin
Publikováno v:
Developmental Dynamics.
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 474:63-81
Experimental and clinical evidence suggests that diabetic subjects are predisposed to a distinct cardiovascular dysfunction, known as diabetic cardiomyopathy (DCM), which could be an autonomous disease independent of concomitant micro and macrovascul