Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Vijaya Sarangthem"'
Multifunctional elastin-like polypeptide nanocarriers for efficient miRNA delivery in cancer therapy
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-24 (2024)
Abstract Background The exogenous delivery of miRNA to mimic and restore miRNA-34a activity in various cancer models holds significant promise in cancer treatment. Nevertheless, its effectiveness is often impeded by challenges, including a short half
Externí odkaz:
https://doaj.org/article/d8f88be1330842fbaaca5ff448507bb2
Publikováno v:
Biomaterials and Biosystems, Vol 6, Iss , Pp 100050- (2022)
Successful gene delivery depends on the entry of negatively charged DNAs and oligonucleotides across the various barriers of the tumor cells and localization into the nucleus for its transcription and protein translation. Here, we have reported a the
Externí odkaz:
https://doaj.org/article/876c039849de46c5aa8f0c90c9c3c127
Publikováno v:
Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background The successful deliveries of siRNA depend on their stabilities under physiological conditions because greater in vivo stability enhances cellular uptake and enables endosomal escape. Viral-based systems appears as most efficient a
Externí odkaz:
https://doaj.org/article/177d5d071832423dbaf4264fde0e3407
Autor:
Thoudam Debraj Singh, Jae Eon Lee, Kwang Hee Son, Bo Ra Lee, Sang Kyoon Kim, Deepak Gulwani, Vijaya Sarangthem, Yong Hyun Jeon
Publikováno v:
Cells, Vol 12, Iss 3, p 470 (2023)
Previously, we reported that an inverse agonist of estrogen-related receptor gamma (ERRγ), GSK5182, enhances sodium iodide (Na+/I−) symporter (NIS) function through mitogen-activated protein (MAP) kinase signaling in anaplastic thyroid cancer cell
Externí odkaz:
https://doaj.org/article/d17adb6f688548aea488877825df8cff
Autor:
Vijaya Sarangthem, Harshita Sharma, Mohini Mendiratta, Ranjit Kumar Sahoo, Rang-Woon Park, Lalit Kumar, Thoudam Debraj Singh, Sujata Mohanty
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1151 (2022)
Regenerative medicine using stem cells offers promising strategies for treating a variety of degenerative diseases. Regulation of stem cell behavior and rejuvenate senescence are required for stem cells to be clinically effective. The extracellular m
Externí odkaz:
https://doaj.org/article/2e7aae115e2848188b76b08f8156bec9
Construction and application of elastin like polypeptide containing IL-4 receptor targeting peptide.
Autor:
Vijaya Sarangthem, Eun A Cho, Sang Mun Bae, Thoudam Debraj Singh, Sun-Ji Kim, Soyoun Kim, Won Bae Jeon, Byung-Heon Lee, Rang-Woon Park
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81891 (2013)
Various human solid tumors highly express IL-4 receptors which amplify the expression of some of anti-apoptotic proteins, preventing drug-induced cancer cell death. Thus, IL-4 receptor targeted drug delivery can possibly increase the therapeutic effi
Externí odkaz:
https://doaj.org/article/cf7b4f912d5d4ebe959319e0d19a6f4e
Publikováno v:
Asian Pacific Journal of Cancer Prevention. 24:375-387
Autor:
Yunjae Kim, Young-Hyun Jeon, Vijaya Sarangthem, Alnawaz Rehemtulla, Rang Woon Park, Aena Yi, Thoudam Debraj Singh, Byung-Heon Lee
Publikováno v:
International Journal of Nanomedicine
Vijaya Sarangthem,1,2,* Aena Yi,1,* Yunjae Kim,1 Alnawaz Rehemtulla,3 Byung-Heon Lee,1 Young Hyun Jeon,4 Thoudam Debraj Singh,5 Rang-Woon Park1 1Department of Biochemistry and Cell Biology, School of Medicine, and Cell & Matrix Research Insti
Publikováno v:
Adv Wound Care (New Rochelle)
Significance: Wound dressing based on naturally derived polymer provides a useful platform for treatment of skin injuries. Owing to the high mechanical strength and tunable structural and physicochemical properties of human elastin-like polypeptides
Publikováno v:
International Journal of Biological Macromolecules. 234:123664