Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Vijaya Kumar Marri"'
Autor:
Srinivas Bandaru, Hema Prasad Mundluru, Someswar Rao Sagurthi, Ramesh Kumar Kattamuri, Vijaya Kumar Marri, Madhavi Mangalarapu, Jyothy Akka, Anuraj Nayarisseri, Pramod Tarigopula, Swetha Vinukonda
Publikováno v:
Gene. 592:15-22
Thr164Ile polymorphism in the ADRB2 gene encoding β2 adrenergic receptor (β2AR) has its functional consequence in declining ligand-receptor interactions and depressed coupling of β2AR to adenylcyclase. In the present study, we sought to evaluate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b8bcb014f96110c633cc7dc7304e04c
https://doi.org/10.1016/j.gene.2016.07.043
https://doi.org/10.1016/j.gene.2016.07.043
Autor:
Anuraj Nayarisseri, Arash Boroumand Nasr, Suresh Gudala, Ramesh Kumar Kattamuri, Chandana Lakkaraju, Deepika Ponnala, Someshwar Rao Sagurthi, Srinivas Bandaru, Vijaya Kumar Marri
Publikováno v:
Bioinformation
Mammalian target of rapamycin (mTOR) is a key regulator of cell growth, proliferation and angiogenesis. mTOR signaling is frequently hyper activated in a broad spectrum of human cancers thereby making it a potential drug target. The current drugs ava
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2f6b86d8d82e0846ba04757a005ff2c
http://europepmc.org/articles/PMC4512006
http://europepmc.org/articles/PMC4512006
Publikováno v:
Inflammation. 38:409-414
Transforming growth factor-beta 1 (TGF-β1) is a multifunctional cytokine that plays a pivotal role in airway remodeling observed in the asthmatic airways. C to T base substitution at -509 promoter position in the TGF-β1 gene leads to its increased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5e46b19e59aa6daa42832b3ac97614f
https://doi.org/10.1007/s10753-014-0045-5
https://doi.org/10.1007/s10753-014-0045-5
Structure based virtual screening of ligands to identify cysteinyl leukotriene receptor 1 antagonist
Autor:
Purnima Kovuri, Anuraj Nayarisseri, Vijaya Kumar Marri, Sabeen Ikram, Amandeep Girdhar, Srinivas Bandaru, Deepti Raj Mittal, Ravi Gv, Priyadarshani Kasera
Publikováno v:
Bioinformation
Montelukast and Zafirlukast are known leukotriene receptor antagonists prescribed in asthma treatment. However, these fall short as mono therapy and are frequently used in combination with inhaled glucocorticosteroids with or without long acting beta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da78d7cd2bd0de111b9f9ce5f34ef48b
https://doi.org/10.6026/97320630010652
https://doi.org/10.6026/97320630010652
Autor:
Srinivas Bandaru, Jyothy Akka, Deepika Ponnala, Mallika Alvala, Hema Prasad Mundluru, Vijaya Kumar Marri
Publikováno v:
Inflammation. 38(6)
β2-Adrenergic receptor (β2-AR) plays a crucial role in asthma pathophysiology by regulating, processes of the lung function, and clinical response to bronchodilators. The +46G>A- Gly16Arg polymorphism in the gene encoding β2 adrenergic receptor (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::546d0aa42cdf22ff97d34ba60040ed42
https://pubmed.ncbi.nlm.nih.gov/26071206
https://pubmed.ncbi.nlm.nih.gov/26071206
Autor:
Geet Tiwari, Jyothy Akka, Hema Prasad Mundluru, Srinivas Bandaru, Venkata Ravi Gutlapalli, Mallika Alvala, Anuraj Nayarisseri, Vijaya Kumar Marri
Publikováno v:
Current topics in medicinal chemistry. 15(1)
Salbutamol forms an important and widely administered β2 agonist prescribed in the symptomatic treatment of bronchial asthma. Unfortunately, a subset of patients show refractoriness to it owing to ADRB2 gene variant (rs 1800888). The variant substit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91cc912fc530cc02f7f379d520a94fff
https://pubmed.ncbi.nlm.nih.gov/25579570
https://pubmed.ncbi.nlm.nih.gov/25579570