Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Vijaya Bhaskara Reddy Iska"'
Autor:
Vidya Katangoor, Suresh Poudapally, M.S. Bethu, Venkateswara Rao Janapala, Vijaya Bhaskara Reddy Iska, Narender Pottabathini, Somesh Sharma, Subhabrata Sen, Loka Reddy Velatooru, Shankar Battu
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:1923-1928
A robust economic approach to N-(quinazoline-4-yl)sulfonamides was developed and synthesized different aryl, hetero aryl, alkyl and cyclopropyl sulfonamides in excellent yields. All the compounds were evaluated for cytotoxic affinity to SKOV3, DU145,
Autor:
Anamitra Chatterjee, John T. Markiewicz, Olaf Wiest, Vijaya Bhaskara Reddy Iska, Casey C. Cosner, Douglas J. Schauer, Tobias Ankner, Joakim Löfstedt, Paul Helquist, Tyler Hulett, Steven J. Corden, Joshua Richer
Publikováno v:
European Journal of Organic Chemistry. 2013:162-172
(R)-(+)-Trichostatic acid and (R)-(+)-trichostatin A (TSA) are natural products that have attracted considerable attention in the field of epigenetic therapies. TSA in particular is a naturally occurring hydroxamic acid having potent activity as a hi
Publikováno v:
The Journal of Organic Chemistry. 75:1325-1328
An efficient silver-catalyzed desymmetrization of amino diynes via hydroamination is reported. A variety of functionalized 1-pyrroline derivatives were synthesized in 73% to 88% isolated yields (98% by (1)H NMR in some cases). The usefulness of this
Autor:
Adeline Adrien, Hans-Joachim Gais, Shashi Kant Tiwari, Gadamsetti S. Babu, Vijaya Bhaskara Reddy Iska
Publikováno v:
Tetrahedron Letters. 48:7102-7107
Chiral cyclic and acyclic allyl aminosulfoxonium ylides have been generated from aminosulfoxonium-substituted β,γ-unsaturated α-amino acids (method A) and 1-alkenyl aminosulfoxonium salts (method B) upon treatment with DBU. Their application to th
Autor:
Gadamsetti S. Babu, Hans-Joachim Gais, Gerhard Raabe, Markus Günter, Shashi Kant Tiwari, Andreas Lindenmaier, Vijaya Bhaskara Reddy Iska, Stefan Koep, Leleti Rajender Reddy, Franz Köhler
Publikováno v:
Journal of the American Chemical Society. 128:7360-7373
Methylation of the enantiopure functionalized vinyl sulfoximines 5a-e and 14a-d followed by a F- ion or DBU-mediated isomerization of the vinyl aminosulfoxonium salts 7a-e and 15a-d, respectively, gave the allyl aminosulfoxonium salts 10a-e and 17a-d
Autor:
Olaf Wiest, Anamitra Chatterjee, Joshua Richer, Tyler Hulett, Vijaya Bhaskara Reddy Iska, Paul Helquist
Publikováno v:
Organic Letters. 12:832-834
An efficient synthesis of rac-trichostatic acid (1) and its analogues is reported starting from a commercially available aldehyde. Further manipulations of rac-1 led to rac-trichostatin A (TSA). Construction of the desired molecular architecture enta