Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Vijaya B, Kumar"'
Publikováno v:
Pharmaceutical Nanotechnology. 8:207-224
Background: Carvedilol (CD), a non-selective beta-blocker, is indicated for the management of mild to moderate congestive heart failure. After oral administration, CD is rapidly absorbed with an absolute bioavailability of 18-25% because of low solub
Publikováno v:
Journal of Neurotrauma. 36:1869-1875
Traumatic brain injury (TBI) has many long-term consequences, including impairment in memory and changes in mood. Glycogen synthase kinase 3β (GSK-3β) in its phosphorylated form (p-GSK-3β) is considered to be a major contributor to memory problems
Autor:
Balakrishna Ganni, Rajesh Kumar, Mohit Jain, Vijaya B. Kumar, Sujeet Shrivastava, Pramod Kumar
Publikováno v:
Chemical Methodologies, Vol 3, Iss Issue 2. pp. 145-275, Pp 145-165 (2019)
A new sensitive, specific, precise and accurate stability indicating reverse phase high performance liquid chromatographic (RP-HPLC) method was developed and validated for the determination of related substances of telmisartan drug substance. The met
Publikováno v:
European Journal of Pharmacology. 845:65-73
3,4-Dihydroxyphenylacetaldehyde (DOPAL), the monoamine oxidase (MAO) metabolite of dopamine, plays a role in pathogenesis of Parkinson disease, inducing α-synuclein aggregation. DOPAL generates discrete α-synuclein aggregates. Inhibiting this aggre
Autor:
Roopa R. Mendagudli, Dayalaxmi Tukaram Shedole, Vijaya B. Kumar, Shubha Bakkappa Devalgi, G S Vidya
Publikováno v:
International Journal of Community Medicine and Public Health. :552-557
Background: Tuberculosis continues to be a major public health problem in our country and is the largest cause of loss of healthy life years in the productive age. Revised National Tuberculosis Control Programme depends on passive reporting of the ch
Publikováno v:
International Journal of Pharma and Bio Sciences. 8
Autor:
Thomas L. Platt, Jessica L. Ripley, M. Paul Murphy, Susan A. Farr, Michael L. Niehoff, John E. Morley, D. Allan Butterfield, Zhaoshu Zhang, Vijaya B. Kumar, Rukhsana Sultana
Publikováno v:
Free Radical Biology and Medicine. 67:387-395
Glycogen synthase kinase (GSK) -3β is a multifunctional protein that has been implicated in the pathological characteristics of Alzheimer’s disease (AD), including the heightened levels of neurofibrillary tangles, amyloid-beta (Aβ) and neurodegen
Autor:
Sarah Förster, Marzia Perluigi, Giovanna Cenini, Susan A. Farr, John E. Morley, Ada Fiorini, Vijaya B. Kumar, Rukhsana Sultana, Jian Cai, Michael L. Niehoff, Chiara Cini, D. Allan Butterfield, Jon B. Klein
Publikováno v:
Free Radical Biology and Medicine. 65:1-14
Amyloid β-peptide (Aβ) plays a central role in the pathophysiology of Alzheimer's disease (AD) through the induction of oxidative stress. This peptide is produced by proteolytic cleavage of amyloid precursor protein (APP) by the action of β- and
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1822(5):650-656
The senescence accelerated mouse (SAMP8) is a spontaneous animal model of overproduction of amyloid precursor protein (APP) and oxidative damage. It develops early memory disturbances and changes in the blood–brain barrier resulting in decreased ef
Publikováno v:
Current Pharmaceutical Design. 18:1123-1130
The senescence accelerate mouse P8 (SAMP8) is an excellent model of early learning and memory problems. A number of studies have shown that it has cholinergic deficits, oxidative damage, alterations in membrane lipids and circadian rhythm disturbance