Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Vijay S. Reddy"'
Publikováno v:
Viruses, Vol 14, Iss 2, p 414 (2022)
Various adenoviruses are being used as viral vectors for the generation of vaccines against chronic and emerging diseases (e.g., AIDS, COVID-19). Here, we report the improved capsid structure for one of these vectors, human adenovirus D26 (HAdV-D26),
Externí odkaz:
https://doaj.org/article/8eab7e75d5bf4922b0c247682e3fd303
Autor:
Vijay S. Reddy, John E. Johnson, Daniel Jorge Montiel-Garcia, Charles L. Brooks, Phuong T. Ho, Nelly Beatriz Santoyo-Rivera, Mauricio Carrillo-Tripp
Publikováno v:
Nucleic Acids Research
VIrus Particle ExploreR data base (VIPERdb) (http://viperdb.scripps.edu) is a curated repository of virus capsid structures and a database of structure-derived data along with various virus specific information. VIPERdb has been continuously improved
Autor:
John P. Atkinson, Shao-Chia Lu, Mallory A. Turner, M. Kathryn Liszewski, Christopher Chen, Jack R. Hemsath, A. Manuel Liaci, Vijay S. Reddy, Tien V. Nguyen, Karolina Cupelli, Thilo Stehle, Michael A. Barry, Brian J. Parrett, Jeffrey D. Rubin
Publikováno v:
J Virol
Human adenovirus serotype 26 (Ad26) is used as a gene-based vaccine against SARS-CoV-2 and HIV-1. Yet, its primary receptor portfolio remains controversial, potentially including sialic acid, CAR, integrins, and CD46. We and others have shown that Ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cff3db6aded9187d4862fcb3fdcc0f4
https://europepmc.org/articles/PMC8826919/
https://europepmc.org/articles/PMC8826919/
Non-polio enteroviruses (NPEVs) cause serious illnesses in young children and neonates including aseptic meningitis, encephalitis, neonatal sepsis and inflammatory muscle disease, among others. Over 100 serotypes have been described to date but excep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f7e1e7ea33ca5c70034dffde5585df
https://doi.org/10.1101/2022.01.31.478566
https://doi.org/10.1101/2022.01.31.478566
Publikováno v:
Journal of structural biology. 214(1)
The antigenic epitope regions of pathogens (e.g., viruses) are recognized by antibodies (Abs) and subsequently cleared by the host immune system, thereby protecting us from disease. Some of these epitopes are conserved among different variants or sub
Autor:
Glen R. Nemerow, Tina-Marie Mullen, Sangita Venkataraman, Vijay S. Reddy, S. Kundhavai Natchiar
Publikováno v:
Journal of Molecular Biology. 430:4132-4141
We report the revised crystal structure of a pseudo-typed human adenovirus at 3.8-Å resolution that is consistent with the atomic models of minor proteins determined by cryo-electron microscopy. The diffraction data from multiple crystals were resca
Autor:
Michael A. Barry, Vijay S. Reddy
Publikováno v:
Subcellular Biochemistry ISBN: 9783030589707
Human adenoviruses (HAdVs) are large (150 MDa), complex, nonenveloped dsDNA viruses that cause self-limiting respiratory, ocular and enteric infections. They are significant health hazard in young, elderly and immuno-compromised populations. Moreover
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d413513124d100e197d6a038753bcbca
https://doi.org/10.1007/978-3-030-58971-4_16
https://doi.org/10.1007/978-3-030-58971-4_16
Autor:
Vijay S, Reddy, Michael A, Barry
Publikováno v:
Sub-cellular biochemistry. 96
Human adenoviruses (HAdVs) are large (150 MDa), complex, nonenveloped dsDNA viruses that cause self-limiting respiratory, ocular and enteric infections. They are significant health hazard in young, elderly and immuno-compromised populations. Moreover
Autor:
Juha T. Huiskonen, Xiaodi Yu, Vahid Abrishami, Vijay S. Reddy, Glen R. Nemerow, Tina-Marie Mullen
Publikováno v:
J Mol Biol
Maturation of adenoviruses is distinguished by proteolytic processing of several interior minor capsid proteins and core proteins by the adenoviral protease and subsequent reorganization of adenovirus core. We report the results derived from the icos
Autor:
Lalit Deshmukh, Ruben D. Elias, Vijay S. Reddy, Wen Ma, Charles D. Schwieters, Rodolfo Ghirlando
Publikováno v:
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America, vol 117, iss 39
Proceedings of the National Academy of Sciences of the United States of America, vol 117, iss 39
Proline-rich domains (PRDs) are among the most prevalent signaling modules of eukaryotes but often unexplored by biophysical techniques as their heterologous recombinant expression poses significant difficulties. Using a "divide-and-conquer" approach