Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Vijay R. More"'
Autor:
Vijay R More, Julie Lao, David G McLaren, Anne-Marie Cumiskey, Beth Ann Murphy, Ying Chen, Stephen Previs, Steven Stout, Rajesh Patel, Santhosh Satapati, Wenyu Li, Edward Kowalik, Daphne Szeto, Andrea Nawrocki, Alessandro Pocai, Liangsu Wang, Paul Carrington
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186586 (2017)
Lipid lowering properties of glucagon have been reported. Blocking glucagon signaling leads to rise in plasma LDL levels. Here, we demonstrate the lipid lowering effects of acute dosing with Glp1r/Gcgr dual agonist (DualAG). All the experiments were
Externí odkaz:
https://doaj.org/article/610ce14e40dc429c826400d13e869211
Autor:
David Serra, Vijay R. More, Steven K. Engle, Matthew Gallacher, Prajakta Shimpi, Michael E. Dunn, Nicholas M.P. King, Thomas G. Manfredi, Kathryn E. Gropp, Heidi M. Colton, Josh Powe, Frederick J. Vetter, Luis A Rodriguez, Kevin Agostinucci
Publikováno v:
Toxicologic Pathology. 45:344-352
Given the proven utility of natriuretic peptides as serum biomarkers of cardiovascular maladaptation and dysfunction in humans and the high cross-species sequence conservation of atrial natriuretic peptides, natriuretic peptides have the potential to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0d2691f50122c454d6677b129f75f2
https://doi.org/10.1177/0192623316634231
https://doi.org/10.1177/0192623316634231
Publikováno v:
Journal of Neurochemistry. 135:1113-1122
Breast cancer resistance protein (Bcrp/Abcg2) localized at the blood-brain barrier (BBB) limits permeability into the brain of many xenobiotics, including pharmacological agents. Peroxisome proliferator-activated receptor α (Pparα), a ligand-activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1409e55c507f711c65fb634c1b144c54
https://doi.org/10.1111/jnc.13389
https://doi.org/10.1111/jnc.13389
Autor:
Angela L. Slitt, Ajay C. Donepudi, Maneesha Paranjpe, Beverly S. Rubin, Prajakta Shimpi, Dana C. Dolinoy, Vijay R. More, Jaclyn M. Goodrich
Publikováno v:
Environmental Health Perspectives
Background: Exposure to chemicals during critical windows of development may re-program liver for increased risk of nonalcoholic fatty liver disease (NAFLD). Bisphenol A (BPA), a plastics component, has been described to impart adverse effects during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::841f655c8174622cebbbc41bbfbe37c6
https://doi.org/10.1289/ehp664
https://doi.org/10.1289/ehp664
Autor:
Alessandro Pocai, Vijay R. More, Santhosh Satapati, David G. McLaren, Paul E. Carrington, Beth Ann Murphy, Liangsu Wang, Edward J. Kowalik, Anne-Marie Cumiskey, Andrea R. Nawrocki, Ying Chen, Steven J. Stout, Daphne Szeto, Wenyu Li, Stephen F. Previs, Julie Lao, Rajesh Patel
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 10, p e0186586 (2017)
PLoS ONE, Vol 12, Iss 10, p e0186586 (2017)
Lipid lowering properties of glucagon have been reported. Blocking glucagon signaling leads to rise in plasma LDL levels. Here, we demonstrate the lipid lowering effects of acute dosing with Glp1r/Gcgr dual agonist (DualAG). All the experiments were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91531f0a46851a96d2bb96ba7c024e6
https://pubmed.ncbi.nlm.nih.gov/29065174
https://pubmed.ncbi.nlm.nih.gov/29065174
Autor:
Tapan K. Chatterjee, Angela L. Slitt, Bingfang Yan, Supriya R. Kulkarni, Jialin Xu, Vijay R. More, Ajay C. Donepudi, Liya Li, Liangran Guo, Neal L. Weintraub
Publikováno v:
Obesity. 23:335-344
Objective To evaluate whether Nrf2 deficiency impacts insulin resistance and lipid accumulation in liver and white adipose tissue. Methods Lepob/ob mice (OB) with targeted Nrf2 deletion (OB-Nrf2KO) were generated. Pathogenesis of obesity and type 2 d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ff5770a86c8a79bd3852d2ff9e46584
https://doi.org/10.1002/oby.20929
https://doi.org/10.1002/oby.20929
Autor:
James P. Luyendyk, Jialin Xu, Vijay R. More, Prajakta Shimpi, Masayuki Yamamoto, Angela L. Slitt, Clyde Belgrave
Publikováno v:
Free Radical Biology and Medicine. 61:85-94
The Nuclear factor-E2 related factor 2 (Nrf2)-Kelch-like ECH-associated protein 1 (Keap1) pathway upregulates antioxidant and biotransformation enzyme expression to counter cellular oxidative stress. The contribution of Nrf2 to other cellular functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8802532919e3f8d09c8f71a574b2400b
https://doi.org/10.1016/j.freeradbiomed.2013.03.007
https://doi.org/10.1016/j.freeradbiomed.2013.03.007
Autor:
Ruitang Deng, Bingfang Yan, Yurong Lai, Matthew A. Stoner, Xiulong Song, Leila Valanejad, Xi Qiu, Angela L. Slitt, Alexander Vasilenko, Weikang Chen, Vijay R. More, Yuan Chen
Publikováno v:
Hepatology. 57:1530-1541
As a canalicular bile acid effluxer, the bile salt export pump (BSEP) plays a vital role in maintaining bile acid homeostasis. BSEP deficiency leads to severe cholestasis and hepatocellular carcinoma (HCC) in young children. Regardless of the etiolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98530e9a3cae2fb698a86920b59c8982
https://doi.org/10.1002/hep.26187
https://doi.org/10.1002/hep.26187
Autor:
Vijay R. More, Jialin Xu, Angela L. Slitt, Lauren M. Aleksunes, Angela A. Baker, Laura E. Armstrong, Maureen V. Driscoll, Jason R. Richardson, Ajay C. Donepudi
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 27:165-171
Deltamethrin, a type II pyrethroid, is a widely used insecticide. The purpose of this study was to determine whether perinatal deltamethrin exposure altered the expression of adipogenic and lipogenic genes in white adipose tissue (WAT) in adult pups.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b47a7fb980f32d50f87f6b35a6c6f06
https://doi.org/10.1002/jbt.21477
https://doi.org/10.1002/jbt.21477