Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Vijay P.S. Rawat"'
Autor:
Silvia Thoene, Tamoghna Mandal, Naidu M. Vegi, Leticia Quintanilla-Martinez, Reinhild Rösler, Sebastian Wiese, Klaus H. Metzeler, Tobias Herold, Torsten Haferlach, Konstanze Döhner, Hartmut Döhner, Luisa Schwarzmüller, Ursula Klingmüller, Christian Buske, Vijay P.S. Rawat, Michaela Feuring-Buske
Publikováno v:
Blood Advances, Vol 3, Iss 22, Pp 3729-3739 (2019)
Abstract: Acute erythroid leukemia (AEL) is a rare and aggressive form of acute leukemia, the biology of which remains poorly understood. Here we demonstrate that the ParaHox gene CDX4 is expressed in patients with acute erythroid leukemia, and that
Externí odkaz:
https://doaj.org/article/4debbd15adfa4c6b8bf9b4abbc5e7e12
Autor:
Naidu M. Vegi, Josef Klappacher, Franz Oswald, Medhanie A. Mulaw, Amit Mandoli, Verena N. Thiel, Shiva Bamezai, Kristin Feder, Joost H.A. Martens, Vijay P.S. Rawat, Tamoghna Mandal, Leticia Quintanilla-Martinez, Karsten Spiekermann, Wolfgang Hiddemann, Konstanze Döhner, Hartmut Döhner, Hendrik G. Stunnenberg, Michaela Feuring-Buske, Christian Buske
Publikováno v:
Cell Reports, Vol 16, Iss 2, Pp 498-507 (2016)
Homeobox genes are known to be key factors in leukemogenesis. Although the TALE family homeodomain factor Meis1 has been linked to malignancy, a role for MEIS2 is less clear. Here, we demonstrate that MEIS2 is expressed at high levels in patients wit
Externí odkaz:
https://doaj.org/article/568dc4d735944c92a3a29ec0ac42945f
Autor:
Michaela Feuring-Buske, Hartmut Döhner, Alessandro Pastore, Christian Buske, Vijay P.S. Rawat, Susann Ihme, Silvia Thoene, Avinash A. Rasalkar, Deepak Bararia, Konstanze Döhner, Naidu M. Vegi, Leticia Quintanilla-Fend, Maria Götze
Publikováno v:
Web of Science
Haematologica
Haematologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fe6fdd18973cfb5b0e46f8a85c0fdeb
https://doi.org/10.3324/haematol.2019.223297
https://doi.org/10.3324/haematol.2019.223297
Autor:
Vijay P.S. Rawat, Alex Jose Pulikkottil, Leticia Quintanilla-Martinez, Naidu M. Vegi, Ursula Kohlhofer, Shiva Bamezai, Tobias Ammer, Amit U. Sinha, Christian Buske, Fabian Mohr, Kristin Feder, Tamoghna Mandal
Publikováno v:
Leukemia. 36(2)
Acute myeloid leukemia (AML) is considered a poor prognosis malignancy where patients exhibit altered glucose metabolism and stem cell signatures that contribute to AML growth and maintenance. Here, we report that the epigenetic factor, Ten-Eleven Tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e19e17c592b9901ee9f1fe8cfe89369
https://pubmed.ncbi.nlm.nih.gov/34462525
https://pubmed.ncbi.nlm.nih.gov/34462525
Autor:
Christian Buske, Daniel Sauter, Mirco Glitscher, Mirja Harms, Hartmut Doehner, Jan Muench, Vijay P.S. Rawat, Eberhard Hildt, Lisa M. Kaiser, Konstanze Doehner
The G protein-coupled receptor (GPCR) and chemokine receptor CXCR4 plays an essential role in tumor initiation and maintenance. This is exemplified in acute myeloid leukemia (AML), where CXCL12-mediated CXCR4 signaling plays a pivotal role for the cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::271e8bf56fce6ae2fed52c5d2071e22c
https://doi.org/10.1101/2021.03.11.434944
https://doi.org/10.1101/2021.03.11.434944
Autor:
Vijay P.S. Rawat, Christian Buske, Lisa M. Kaiser, Daniel Tews, Eberhard Hildt, Zachary R. Hunter, Mirja Harms, Mirco Glitscher, Jan Münch, Daniel Sauter
Publikováno v:
Cancers, 13(4):826
Cancers
Cancers, Vol 13, Iss 826, p 826 (2021)
Volume 13
Issue 4
Cancers
Cancers, Vol 13, Iss 826, p 826 (2021)
Volume 13
Issue 4
CXCR4 expression and downstream signaling have been identified as key factors in malignant hematopoiesis. Thus, up to 40% of all patients with Waldenström’s macroglobulinemia (WM) carry an activating mutation of CXCR4 that leads to a more aggressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::075e782eda39a66f0137dfe63d7f3cc7
https://repository.publisso.de/resource/frl:6431949
https://repository.publisso.de/resource/frl:6431949
Autor:
Irene Gonzalez-Menendez, Paola Caiafa, Lüder-Hinrich Meyer, Fabian Mohr, Vijay P.S. Rawat, Tobias Herold, Deniz Demir, Leticia Quintanilla-Fend, Geertruy te Kronnie, Alex Jose Pulikkottil, Shiva Bamezai, Fabio Ciccarone, Hartmut Döhner, Maria Götze, Michaela Feuring-Buske, Christian Buske, Irmela Jeremias, Elena Fischbein, Klaus-Michael Debatin, Amit U. Sinha, Chiara Borga, Konstanze Döhner
Publikováno v:
Leukemia 35, 389–403 (2020)
Leukemia
Leukemia
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological cancer characterized by skewed epigenetic patterns, raising the possibility of therapeutically targeting epigenetic factors in this disease. Here we report that among differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05765430d5571d4c155eb9fa10d4f63b
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=59126
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=59126
Autor:
Luisa E. Schwarzmüller, Tobias Herold, Christian Buske, Klaus H. Metzeler, Hartmut Döhner, Leticia Quintanilla-Martinez, Torsten Haferlach, Reinhild Rösler, Tamoghna Mandal, Naidu M. Vegi, Sebastian Wiese, Michaela Feuring-Buske, Ursula Klingmüller, Vijay P.S. Rawat, Silvia Thoene, Konstanze Döhner
Publikováno v:
Blood advances. 3(22)
Acute erythroid leukemia (AEL) is a rare and aggressive form of acute leukemia, the biology of which remains poorly understood. Here we demonstrate that the ParaHox gene CDX4 is expressed in patients with acute erythroid leukemia, and that aberrant e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a18cde958efaa659ad326a0f38abe22
https://pubmed.ncbi.nlm.nih.gov/31770439
https://pubmed.ncbi.nlm.nih.gov/31770439
Autor:
Katrin Elisabeth Edmaier-Schröger, Nicole Kirsten, Konstanze Döhner, Hartmut Döhner, Klaus H. Metzeler, Johann M. Kraus, Vijay P.S. Rawat, Michaela Feuring-Buske, Kristin Feder, Christian Buske, Hans A. Kestler
Publikováno v:
Leukemia. 34(4)
Acute myeloid leukemia (AML) is the most common acute leukemia in adults and is propagated by leukemic stem cells (LSCs), often characterized by deregulated Wnt signaling. We previously showed that the central transcriptional mediator of Wnt signalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86cf94b85f1af4261d5bcaa61a5eeba1
https://pubmed.ncbi.nlm.nih.gov/31758089
https://pubmed.ncbi.nlm.nih.gov/31758089
Autor:
Vijay P.S. Rawat, Stefanie Sieste, Anne Stumper, Naidu M. Vegi, Christian Buske, Tanja Weil, Michaela Feuring-Buske, Maksymilian Marek Zegota, Seah Ling Kuan, Sabyasachi Chakrabortty, Sven Rau
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Acute myeloid leukemia (AML) is characterized by relapse and treatment resistance in a major fraction of patients, underlining the need of innovative AML targeting therapies. Here we analysed the therapeutic potential of an innovative biohybrid consi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87a7489c054182da6f01e5caefc9e2f6
https://pubmed.ncbi.nlm.nih.gov/31941913
https://pubmed.ncbi.nlm.nih.gov/31941913