Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Vijay Menon"'
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101828- (2022)
Summary: Mitochondrial membrane potential (MMP) segregates functionally distinct subsets within highly purified hematopoietic stem cells (HSCs). Here, we detail a protocol for FACS isolation of MMP sub-fractions of phenotypically defined mouse and hu
Externí odkaz:
https://doaj.org/article/c622d15ed2f547eba13a1017223ea7b2
Publikováno v:
Redox Biology, Vol 24, Iss , Pp - (2019)
Recently, clinical development of PARP inhibitors (PARPi) expanded from using them as a single agent to combining them with DNA-damaging therapy to derive additional therapeutic benefit from stimulated DNA damage. Furthermore, inhibiting PARP in canc
Externí odkaz:
https://doaj.org/article/cad66155fd064066945a80a9cb449016
Autor:
Vijay Menon, Miao Lin, Raymond Liang, Tasleem Arif, Anagha Menon, Laura Breda, Stefano Rivella, Saghi Ghaffari
β-thalassemias are common hemoglobinopathies due to mutations in the β-globin gene that lead to hemolytic anemias. Premature death of β-thalassemic erythroid precursors results in ineffective erythroid maturation, increased production of erythropo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04ec2fefc8f9a461e72e2c75e30bc087
https://doi.org/10.1101/2022.03.03.482874
https://doi.org/10.1101/2022.03.03.482874
Publikováno v:
IJCAI
We study one-sided matching problems where each agent must be assigned at most one object. In this classic problem it is often assumed that agents specify only ordinal preferences over objects and the goal is to return a matching that satisfies some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2329d8e54168b78346765c0651b984b9
https://doi.org/10.24963/ijcai.2021/45
https://doi.org/10.24963/ijcai.2021/45
Autor:
M. Michael Dcona, Vijay Menon
Publikováno v:
JoLS, Journal of Life Sciences. :11-25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37d4f3830e5ad7ad521453cdcecb7c7e
https://doi.org/10.36069/jols/20190902
https://doi.org/10.36069/jols/20190902
Autor:
Vijay Menon, Selene K. Swanson, Michael P. Washburn, Varsha Ananthapadmanabhan, Fatmata Sesay, Mikhail G. Dozmorov, Larisa Litovchick, James A. DeCaprio, Siddharth Saini, Laurence Florens, Vasily A. Yakovlev
Publikováno v:
Cell Cycle
SummaryHumanDYRK1Agene encoding Dual-specificity tyrosine (Y)- Regulated Kinase 1A (DYRK1A) is a dosage-dependent gene whereby either trisomy or haploinsufficiency result in developmental abnormalities. However, the function and regulation of this im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8dde480993914e9ec8dff4c901d82a0
https://doi.org/10.1080/15384101.2019.1577525
https://doi.org/10.1080/15384101.2019.1577525
Autor:
Raymond Liang, Miao Lin, Deanna L. Benson, Roberta B. Nowak, Nikos Tzavaras, Saghi Ghaffari, Santosh Renuse, Jiajing Qiu, Tasleem Arif, Vijay Menon, Velia Fowler, Akhilesh Pandey, Jerry E. Chipuk, Miguel Fribourg, Boris M. Hartmann
Publikováno v:
Blood Adv
Mammalian red blood cells (RBCs), which primarily contain hemoglobin, exemplify an elaborate maturation process, with the terminal steps of RBC generation involving extensive cellular remodeling. This encompasses alterations of cellular content throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79ee1994c42bb1512f793d98a5caf5d7
https://pubmed.ncbi.nlm.nih.gov/34032849
https://pubmed.ncbi.nlm.nih.gov/34032849
Autor:
Saghi Ghaffari, Vijay Menon
Publikováno v:
Exp Hematol
Erythropoiesis is an intricate process starting in hematopoietic stem cells and leading to the daily production of 200 billion red blood cells (RBCs). Enucleation is a greatly complex and rate-limiting step during terminal maturation of mammalian RBC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52dd36986441fc61239ba4e136633287
https://pubmed.ncbi.nlm.nih.gov/33440185
https://pubmed.ncbi.nlm.nih.gov/33440185
Autor:
Fangming Lin, Jiajing Qiu, Vijay Menon, Jeffrey M. Bernitz, Kateri A. Moore, Raymond Liang, Svetlana Kalmykova, Tasleem Arif, Nikolaos Tzavaras, Miao Lin, Deanna L. Benson, Artem S. Kasianov, Milind Mahajan, Saghi Ghaffari, Dmitri Papatsenko
Publikováno v:
Cell Stem Cell
Summary Quiescence is a fundamental property that maintains hematopoietic stem cell (HSC) potency throughout life. Quiescent HSCs are thought to rely on glycolysis for their energy, but the overall metabolic properties of HSCs remain elusive. Using c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cf225865e367f46559e2f78ec6802ac
https://europepmc.org/articles/PMC8075247/
https://europepmc.org/articles/PMC8075247/
Autor:
Samuel Wood, Prem Menon, Charles A. Ternent, Vijay Menon, Maniamparampil Shashidharan, Moriah Wright, Darcy D Shaw, Noelle Bertelson, Lindsay Taylor
Publikováno v:
Journal of Laparoendoscopic & Advanced Surgical Techniques. 28:1163-1168
To understand the role of case complexity in the learning curve for robotic colorectal surgery.Sixty-two patients who underwent robot-assisted colorectal surgery were retrospectively reviewed. Each case was assigned a category of complexity ranging f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71128315e7b5f6f3d93053d757b26d2e
https://doi.org/10.1089/lap.2016.0411
https://doi.org/10.1089/lap.2016.0411