Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Vijay Kumar Kutala"'
Publikováno v:
Indian Heart Journal, Vol 70, Iss , Pp S120-S125 (2018)
Objectives: Statins are the most commonly prescribed medications for the treatment of atherosclerotic cardiovascular disease. Statin-associated adverse effects occur in ∼10% of patients and are associated with polymorphisms in several key genes cod
Externí odkaz:
https://doaj.org/article/cd3b2ca2a230475e9d7b8196fd56b4fc
Autor:
Kalluri Thishya, Kiran Kumar Vattam, Shaik Mohammad Naushad, Shree Bhushan Raju, Vijay Kumar Kutala
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0191921 (2018)
The objective of the current study was to explore the role of ABCB1 and CYP3A5 genetic polymorphisms in predicting the bioavailability of tacrolimus and the risk for post-transplant diabetes. Artificial neural network (ANN) and logistic regression (L
Externí odkaz:
https://doaj.org/article/9f185bbd24f84842ae5e4037dc45a56a
Autor:
Mala Ganesan, Sheikh Nizamuddin, Shiva Krishna Katkam, Konda Kumaraswami, Uday Kumar Hosad, Limmy Loret Lobo, Vijay Kumar Kutala, Kumarasamy Thangaraj
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164151 (2016)
Coronary artery disease (CAD) is one of the leading causes of mortality worldwide. It is a multi-factorial disease and several studies have demonstrated that the genetic factors play a major role in CAD. Although variations in cholesteryl ester trans
Externí odkaz:
https://doaj.org/article/a14c82cc240c447a9e210ff1c6e09763
Autor:
Shaik Mohammad Naushad, Vijay Kumar Kutala, Suryanarayana Raju Gottumukkala, Raghunadha Rao Digumarti, Yedluri Rupasree, Shree Divyya, Addepalli Pavani
Publikováno v:
Journal of Medical and Allied Sciences, Vol 1, Iss 1, Pp 7-13 (2011)
This study addresses the issues in translating the laboratory derived data obtained during discovery phase of research to a clinical setting using a breast cancer model. Laboratory-based risk assessment indi-cated that a family history of breast canc
Externí odkaz:
https://doaj.org/article/e159b41919ea4143a1d643b57a293132
Publikováno v:
Saudi Journal of Kidney Diseases and Transplantation, Vol 24, Iss 2, Pp 370-372 (2013)
Externí odkaz:
https://doaj.org/article/675d57ea0e9547628f0ec06cf8e212fb
Autor:
Cheruku Apoorva Reddy, Venkateswarlu Somepalli, Trimurtulu Golakoti, Anantha KoteswaraRao Kanugula, Santosh Karnewar, Karthikraj Rajendiran, Nagarjuna Vasagiri, Sripadi Prabhakar, Periannan Kuppusamy, Srigiridhar Kotamraju, Vijay Kumar Kutala
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e89351 (2014)
Although the anti-cancer effects of curcumin has been shown in various cancer cell types, in vitro, pre-clinical and clinical studies showed only a limited efficacy, even at high doses. This is presumably due to low bioavailability in both plasma and
Externí odkaz:
https://doaj.org/article/9ca796f9899c46419c74f82d5d62ba1e
Publikováno v:
Pharmacological Reports. 74:1083-1091
Nateglinide is a meglitinide used for the treatment of type 2 diabetes mellitus. Individual studies demonstrated the association of CYP2C9, SLCO1B1, and MTNR1B variants with the safety and efficacy of nateglinide. The current study aimed to develop a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f330bb4ef5eb009b169681b0eb8ae2b
https://doi.org/10.1007/s43440-022-00400-0
https://doi.org/10.1007/s43440-022-00400-0
Autor:
Tasneem SD Fatima, Syed Tazeem Fathima, Rukmini Mridula Kandadai, Rupam Borgohain, Boddupally Sreenu, Vijay Kumar Kutala
Publikováno v:
Indian Journal of Clinical Biochemistry. 38:262-274
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34d70c8f391f060bd6acbc60d2dec0fb
https://doi.org/10.1007/s12291-022-01046-8
https://doi.org/10.1007/s12291-022-01046-8
Autor:
Vijay Kumar Kutala, Salman A. H. Alrokayan, Mekala Janaki Ramaiah, Tajamul Hussain, Shaik Mohammad Naushad
Publikováno v:
Pharmacological Reports. 73:278-287
Several genetic variants of thiopurine metabolic pathway are associated with 6-thiopurine-mediated leucopenia. A population-based evaluation of these variants lays the foundation for Pharmacogenetic-guided thiopurine therapy. A total of 2000 subjects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::722a4f1337d28f053eadf6da626e2953
https://doi.org/10.1007/s43440-020-00158-3
https://doi.org/10.1007/s43440-020-00158-3
Publikováno v:
Molecular Biology Reports. 47:6693-6703
Depletion of S-adenosyl methionine and 5-methyltetrahydrofolate; and elevation of total plasma homocysteine were documented in CAD patients, which might modulate the gene-specific methylation status and alter their expression. In this study, we have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a98a1bb9a5ef73c7c59afeb7fb845209
https://doi.org/10.1007/s11033-020-05723-w
https://doi.org/10.1007/s11033-020-05723-w