Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Vijay Kondreddy"'
Autor:
Vijay Kondreddy, Rajkumar Banerjee, B. L. A. Prabhavathi Devi, Kathirvel Muralidharan, Selvakumar Piramanayagam
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract The proinflammatory cytokines and arachidonic acid (AA)-derived eicosanoids play a key role in cartilage degeneration in osteoarthritis (OA). The lysophosphatidylcholine acyltransferase 3 (LPCAT3) preferentially incorporates AA into the memb
Externí odkaz:
https://doaj.org/article/52472aa7c2d5446e9b54ee1db13f2dc1
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract Crohn’s disease and ulcerative colitis are the two forms of disorders of the human inflammatory bowel disease with unknown etiologies. Endothelial cell protein C receptor (EPCR) is a multifunctional and multiligand receptor, which is expre
Externí odkaz:
https://doaj.org/article/85c508b614b942408bc8046a59867658
Autor:
Vijay Kondreddy, Shiva Keshava, Kaushik Das, Jhansi Magisetty, L. Vijaya Mohan Rao, Usha R. Pendurthi
Publikováno v:
Blood. 140:1549-1564
Deep vein thrombosis (DVT) is the third most common cause of cardiovascular mortality. Several studies suggest that DVT occurs at the intersection of dysregulated inflammation and coagulation upon activation of inflammasome and secretion of interleuk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34a294b7bffc20e51f7b5e9672718f02
https://doi.org/10.1182/blood.2022016424
https://doi.org/10.1182/blood.2022016424
Autor:
Charles T. Esmon, Usha R. Pendurthi, L. Vijaya Mohan Rao, Vijay Kondreddy, Shabbir A. Ansari, Kaushik Das, Shiva Keshava, John H. Griffin
Publikováno v:
Blood. 137:3428-3442
Recombinant factor FVIIa (rFVIIa) is used as a hemostatic agent to treat bleeding disorders in hemophilia patients with inhibitors and other groups of patients. Our recent studies showed that FVIIa binds endothelial cell protein C receptor (EPCR) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d88ed033ebf717637c8edaddc65784c1
https://doi.org/10.1182/blood.2020008417
https://doi.org/10.1182/blood.2020008417
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Supplemental Digital Content is available in the text.
Objective: In response to inflammatory insult, endothelial cells express cell adhesion molecules and TF (tissue factor), leading to increased adhesion of leukocytes to the endothelium and ac
Objective: In response to inflammatory insult, endothelial cells express cell adhesion molecules and TF (tissue factor), leading to increased adhesion of leukocytes to the endothelium and ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::494a99064d15c67ef0d600c947e93c63
http://europepmc.org/articles/PMC8147699
http://europepmc.org/articles/PMC8147699
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective: Recent studies showed that FVIIa (factor VIIa), upon binding to EPCR (endothelial cell protein C receptor), elicits endothelial barrier stabilization and anti-inflammatory effects via activation of PAR (protease-activated receptor)-1–med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f423927bf382473cbae69a9de41711da
https://doi.org/10.1161/atvbaha.120.314244
https://doi.org/10.1161/atvbaha.120.314244
Autor:
Jhansi Magisetty, Vijay Kondreddy, Shiva Keshava, Kaushik Das, Charles T. Esmon, Usha R. Pendurthi, L. Vijaya Mohan Rao
Publikováno v:
Blood
Recurrent spontaneous or trauma-related bleeding into joints in hemophilia leads to hemophilic arthropathy (HA), a debilitating joint disease. Treatment of HA consists of preventing joint bleeding by clotting factor replacement, and in extreme cases,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c76d74744d0ebd091d4cf36226c4c595
https://pubmed.ncbi.nlm.nih.gov/35511191
https://pubmed.ncbi.nlm.nih.gov/35511191
Autor:
Jue Wang, Usha R. Pendurthi, Vijay Kondreddy, Shiva Keshava, Charles T. Esmon, L. Vijaya Mohan Rao
Publikováno v:
Blood. 131:2379-2392
Recent studies show that endothelial cell protein C receptor (EPCR) interacts with diverse ligands, in addition to its known ligands protein C and activated protein C (APC). We showed in earlier studies that procoagulant clotting factor VIIa (FVIIa)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea46fdf005afee1808cb29c45cc4ea5
https://doi.org/10.1182/blood-2017-10-813527
https://doi.org/10.1182/blood-2017-10-813527
Publikováno v:
Immunopharmacology and Immunotoxicology. 38:153-161
The anti-inflammatory properties of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and non-steroidal anti-inflammatory drugs overlap in many ways. The aim of this study was to examine the individual and synergetic anti-inflammatory effects o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee330b489c62ff3e7359b8726ae805eb
https://doi.org/10.3109/08923973.2016.1147578
https://doi.org/10.3109/08923973.2016.1147578
Publikováno v:
Blood. 134:481-481
Endothelial cell protein C receptor (EPCR) interacts with diverse ligands, in addition to its known ligands protein C and activated protein C (APC). We reported earlier that procoagulant clotting factor VIIa (FVIIa) binds EPCR with the same affinity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be863de93c2654ae59bfadd71bfa2300
https://doi.org/10.1182/blood-2019-124976
https://doi.org/10.1182/blood-2019-124976