Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Vijay K. Sikand"'
Publikováno v:
Clinical Infectious Diseases. 47:188-195
Background. Tests to determine serum antibody levels-the 2-tier sonicate immunoglobulin M (IgM) and immunoglobulin G (IgG) enzyme-linked immunosorbent assay (ELISA) and Western blot method or the IgG of the variable major protein-like sequence-expres
Autor:
Gail McHugh, Lisa J. Glickstein, Vijay K. Sikand, Kathryn L. Jones, Allen C. Steere, Nitin Damle
Publikováno v:
Journal of Clinical Microbiology. 44:4407-4413
Three genetic markers of Borrelia burgdorferi have been associated with disseminated disease: the OspC type, the 16S-23S rRNA intergenic spacer type (RST), and vlsE . Here, we modified previous methods so as to identify the three markers by PCR and r
Autor:
Raymond W. Ryan, Andrew Spielman, Timothy J. Lepore, Linda Closter, David H. Persing, Vijay K. Sikand, Kathleen McKay, Diane Christianson, Peter J. Krause, Sam R. Telford, Joseph Gadbaw, Justin D. Radolf
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 68:431-436
Human infection due to Babesia microti has been regarded as infrequent and a condition primarily affecting the elderly or immunocompromised. To determine whether risk in endemic sites may be increasing relative to that of Borrelia burgdorferi and to
Autor:
Vijay K. Sikand, Kathleen McKay, Charles Thompson, David H. Persing, Peter J. Krause, Linda Closter, Andrew Spielman, Justin D. Radolf, Timothy J. Lepore, Ronald Lentz, Sam R. Telford, Diane Christianson
Publikováno v:
Clinical Infectious Diseases. 34:1184-1191
To determine whether a unique group of clinical and laboratory manifestations characterize certain major deer tick-transmitted human pathogens in North America, we compared the symptoms, short-term complications, and laboratory test results of New En
Autor:
Timothy J. Lepore, Diane Pearl, Georgine Burke, Peter J. Krause, Joseph Gadbaw, Jaber Azlanzadeh, Andrew Spielman, Sam R. Telford, Peter Brassard, Vijay K. Sikand, Diane Christianson, Debra McGrath
Publikováno v:
New England Journal of Medicine. 343:1454-1458
Babesiosis is a tick-borne, malaria-like illness known to be enzootic in southern New England. A course of clindamycin and quinine is the standard treatment, but this regimen frequently causes adverse reactions and occasionally fails. A promising alt
Autor:
Robert T. Schoen, Dennis Parenti, Michael C. Caldwell, C. Van Hoecke, Charles Buscarino, Vijay K. Sikand, Marc Gillet
Publikováno v:
Clinical Therapeutics. 22:315-325
Objectives This study compared the tolerability of a Lyme disease vaccine administered intramuscularly at 0 and 1 months with that of a vaccine administered at 0, 1, and 2 months to determine (1) whether adding a third dose of vaccine 1 month after t
Autor:
Allen C. Steere, Robert T. Schoen, David S. Krause, John Nowakowski, Vijay K. Sikand, Sabine Laukamp, Dennis Parenti, Christopher H. Schmid, Charles Buscarino, François Meurice, Erol Fikrig
Publikováno v:
New England Journal of Medicine. 339:209-215
Background The risk of acquiring Lyme disease is high in areas in which the disease is endemic, and the development of a safe and effective vaccine is therefore important. Methods We conducted a multicenter, double-blind, randomized trial involving 1
Publikováno v:
Journal of Infectious Diseases. 171:1371-1374
To determine the incidence and cumulative frequency of Lyme disease in a school-aged population in an area in which Lyme disease is endemic, serum specimens were obtained before and after the 1990-1992 tick seasons from 410 middle and high school stu
Autor:
Nitin Damle, Vijay K. Sikand, Brian J. Moore, Allen C. Steere, Lisa J. Glickstein, Tara Bledsoe
Publikováno v:
Infection and Immunity. 71:6051-6053
In a study of cytokine production ex vivo by Borrelia burgdorferi -stimulated peripheral blood mononuclear cells from 27 patients with culture-positive erythema migrans, production of inflammatory cytokines predominated, particularly gamma interferon
Autor:
Allen C. Steere, Vijay K. Sikand
Publikováno v:
New England Journal of Medicine. 348:2472-2474
To the Editor: A trial of vaccination against Lyme disease provided an opportunity for us to determine the relative frequencies of the presenting manifestations of Lyme disease and the outcomes of treatment in a large population.1 Our goal was to ide