Výsledky vyhledávání - "Vijay K. Chadha"

Uncompetitive Inhibitors of Alcohol Dehydrogenases

Autor: Kristine B. Berst, Heeyeong Cho, Michael Scholze, John F. Schindler, S. Ramaswamy, Kevin G. Leidal, Bryce V. Plapp, Vijay K. Chadha

Publikováno v: Advances in Experimental Medicine and Biology ISBN: 9781461371465

Selective inhibitors of alcohol dehydrogenases could be useful for prevention of poisoning due to metabolism of alcohols, such as methanol or ethylene glycol, that lead to toxic products (Jacobsen and McMartin, 1997). Good inhibitors could also be us

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::96d2b63b064d540583341e56ff8edf12
https://doi.org/10.1007/978-1-4615-4735-8_36

Zobrazit plný text záznamu

Bridgehead Nitrogen Heterocycles. Part-V. Syntheses of s-Triazolo[3,4-b][ 1,3,4,]benzothiadiazines, s-'Triazolo[3,4-b][1 ,3,4]thiadiazines, s-Triazolo[3,4-b][ 1 ,3,4]thiadiazino[5,6-b]quinoxaline, lmidazo[ 2, 1 -b ]benzothiazole and Benzimidazo[ 2,1-b] benzothiazole as Potential Antimicrobial A gents

Autor: VIJAY K. CHADHA, SANJAY JOSHI, ANIL BHARGAVA

Department of Chemistry, Department of Zoology, Government Post-Graduate College, Churu-331 001 Manuscript received 10 October 1991, revised 8 September 1992, accepted 21 September 1992 Bridgehead Nitrogen Heterocycles. Part-V. Syntheses of s-Triazol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1e9c8142a4d49d991fb94d0f5c0dec6

Zobrazit plný text záznamu

Bridgehead Nitrogen Heterocycles. Part-V. Syntheses of s-Triazolo[3,4-b][1,3,4,]benzothiadiazines, s-Triazolo[3,4-b][ 1 ,3,4]thiadiazines, s-Triazolo[3,4-b][1,3,4]thiadiazino[5,6-b]quinoxaline, lmidazo[2,1 -b]benzothiazole and Benzimidazo[2,1-b ]benzothiazole as Potential Antimicrobial A gents

Autor: VIJAY K. CHADHA, SANJAY JOSHI, ANIL BHARGAVA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::082724606157f5e1a805ca9960b96dad

Zobrazit plný text záznamu

Bridgehead Nitrogen Heterocycles. Part-II. Reactions of 4-Bromo-3-methyl-1-substituted-5-pyrazolones with 4-Amino-3-mercapto-5-substituted-s-triazoles and Cyclic Thioureas1

Autor: VIJAY K. CHADHA, G. R. SHARMA

Department of Chemistry,Government Post-graduate College, Churu-331 001 Manuscript received 21 July 1988, revised 11 December 1989, accepted 30 March 1990 Bridgehead Nitrogen Heterocycles. Part-II. Reactions of 4-Bromo-3-methyl-1-substituted-5-pyrazo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4356eda10ce72ab572f38d9805f8884d

Zobrazit plný text záznamu

Inhibition by carboxamides and sulfoxides of liver alcohol dehydrogenase and ethanol metabolism

Autor: Vijay K. Chadha, Kevin G. Leidal, Bryce V. Plapp

Publikováno v: Journal of Medicinal Chemistry. 26:916-922

Sulfoxides and amides were tested as inhibitors of liver alcohol dehydrogenase and ethanol metabolism in rats. With both series of compounds, increasing the hydrophobicity resulted in better inhibition, and introduction of polar groups reduced inhibi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12231aacee48f5c97e08adbc33f4bd44
https://doi.org/10.1021/jm00360a024

Zobrazit plný text záznamu

Inhibition of liver alcohol dehydrogenase and ethanol metabolism by 3-substituted thiolane 1-oxides

Autor: Bryce V. Plapp, Kevin G. Leidal, Vijay K. Chadha

Publikováno v: Journal of Medicinal Chemistry. 28:36-40

3-Substituted thiolane 1-oxides (methyl, n-butyl, n-hexyl, and phenyl) were prepared and tested as inhibitors of horse, monkey, and rat liver alcohol dehydrogenases and of ethanol metabolism in rats. These compounds inhibit alcohol oxidation in an un

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::802d48f4257ff4af3a126066250d030e
https://doi.org/10.1021/jm00379a009

Zobrazit plný text záznamu

Heterocyclic system containing bridgehead nitrogen atom. Part III. 3-Substituted-, 2,3-disubstituted-5,6-dihydro-4H-imidazo[2,1-b]thiazoles and 3-substituted-, 2,3-disubstituted-4,5,6,7-tetrahydrothiazolo[3,2-a]pyrimidines

Autor: H. K. Pujari, Vijay K. Chadha

Publikováno v: Canadian Journal of Chemistry. 47:2843-2847

The syntheses of 3-substituted-, 2,3-disubstituted-5,6-dihydro-4H-imidazo[2,1-b]thiazoles and 3-substituted-, 2,3-disubstituted-4,5,6,7-tetrahydrothiazolo[3,2-a]pyrimidines have been achieved by reacting ketones with 2-mercaptoimidazoline and 2-merca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::822c475e3137494657751ed2452a9a5c
https://doi.org/10.1139/v69-471

Zobrazit plný text záznamu

Heterocyclic Systems with Bridgehead Nitrogen Atom : Reactions of 4-amino-5-rnercapto-3-substituted-s-triazoles with Haloketones, Carboxylic acids and α-halo acids

Autor: VIJAY K. CHADHA, G. R. SHARMA

Department of Chemistry, Government Post-Graduate College, Chum-831 001 (Rajasthan) Manuscript received 24 March 1980, accepted 7 August 1980 The reaction of 4-amino-5-mercapto-3-substituted-s-triazoles(I) with ehloranil and α-haloketones furnished

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::065b743ccd8c0f46420aca522c94fd7a

Zobrazit plný text záznamu

Synthesis of 1,6-Bis(2-lmino-3-Allyl-4-Substituted Thiazole-N2yl) Hexane, 1,6 -Bis(2-lmino-3-Allyl-4-Thiazolidinone-N2yl) Hexane and 1 ,6-Bis(1N-Allyl- Thiohydantoin-N3yl) Hexane

Autor: VIJAY K. CHADHA

Department of Chemistry, Government College, Didwana (Rajasthan). Manuscript received 21 December 1976, revised5May 1977, accepted 10 May 1977 Condensationof N,N' allyl hexamethylene bis-thioarea(l) withα-haloketonesandcholoroacetic acidIn presence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190c4d4a0ce06bc7b0f87425b72956cd

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání