Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Vijay, Rajagopal"'
Autor:
Patricia Rojas, Jianming Wang, Giovanni Guglielmi, Martina Mustè Sadurnì, Lucas Pavlou, Geoffrey Ho Duen Leung, Vijay Rajagopal, Fabian Spill, Marco Saponaro
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-28 (2024)
Abstract Background DNA replication progression can be affected by the presence of physical barriers like the RNA polymerases, leading to replication stress and DNA damage. Nonetheless, we do not know how transcription influences overall DNA replicat
Externí odkaz:
https://doaj.org/article/072a3bf961d1417a9d243d2700149b95
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 7, p e1010257 (2022)
Cadherins build up clusters to maintain intercellular contact through trans and cis (lateral) bindings. Meanwhile, interactions between cadherin and the actin cytoskeleton through cadherin/F-actin linkers can affect cadherin dynamics by corralling an
Externí odkaz:
https://doaj.org/article/e3e35065ccbc4ced9f36461848688b75
Autor:
Adam J. Blanch, Juan Nunez-Iglesias, Arman Namvar, Sebastien Menant, Oliver Looker, Vijay Rajagopal, Wai-Hong Tham, Leann Tilley, Matthew W.A. Dixon
Publikováno v:
Journal of Structural Biology: X, Vol 6, Iss , Pp 100056- (2022)
The red blood cell (RBC) is remarkable in its ability to deform as it passages through the vasculature. Its deformability derives from a spectrin-actin protein network that supports the cell membrane and provides strength and flexibility, however que
Externí odkaz:
https://doaj.org/article/f9891ed3d85b4bc4966cf8fee697134c
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 19, Iss S6, Pp 1-14 (2019)
Abstract Background With the advent of new high-throughput electron microscopy techniques such as serial block-face scanning electron microscopy (SBF-SEM) and focused ion-beam scanning electron microscopy (FIB-SEM) biomedical scientists can study sub
Externí odkaz:
https://doaj.org/article/5785f8d1cd7845bc9fbec51a1180f775
Autor:
Xin Jin, Anna Meletiou, Joshua Chung, Agne Tilunaite, Kateryna Demydenko, Eef Dries, Rosa Doñate Puertas, Matthew Amoni, Ashutosh Tomar, Guillaume Gilbert, Piet Claus, Christian Soeller, Vijay Rajagopal, Karin Sipido, H. Llewelyn Roderick
Publikováno v:
Journal of Molecular and Cellular Cardiology. 179:47-59
Publikováno v:
Lab on a Chip. 23:2447-2457
The developed acoustofluidic device realizes microparticle and cell patterning with acoustophoretic force. It combines a planar acoustic resonator and a microstructured surface which provides complex particle formations with sub-wavelength precision.
Autor:
Patrick M. Lelliott, Hong Ming Huang, Matthew W. Dixon, Arman Namvar, Adam J. Blanch, Vijay Rajagopal, Leann Tilley, Cevayir Coban, Brendan J. McMorran, Simon J. Foote, Gaetan Burgio
Publikováno v:
Blood Advances, Vol 1, Iss 26, Pp 2624-2636 (2017)
Abstract: The malaria parasite hijacks host erythrocytes to shield itself from the immune system and proliferate. Red blood cell abnormalities can provide protection from malaria by impeding parasite invasion and growth within the cell or by compromi
Externí odkaz:
https://doaj.org/article/b904422884f74753812651a6cc48230a
Autor:
Vijay Rajagopal, Senthil Arumugam, Peter J. Hunter, Afshin Khadangi, Joshua Chung, Michael Pan
Publikováno v:
Annual Review of Biomedical Data Science. 5:341-366
Modern biology and biomedicine are undergoing a big data explosion, needing advanced computational algorithms to extract mechanistic insights on the physiological state of living cells. We present the motivation for the Cell Physiome Project: a frame
Autor:
David Ladd, Agnė Tilūnaitė, H. Llewelyn Roderick, Christian Soeller, Edmund J. Crampin, Vijay Rajagopal
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Calcium signaling plays a pivotal role in cardiomyocytes, coupling electrical excitation to mechanical contraction of the heart. Determining locations of active calcium release sites, and how their recruitment changes in response to stimuli and in di
Externí odkaz:
https://doaj.org/article/743985bd30454e909e34964579cc24a5
Autor:
Shouryadipta Ghosh, Kenneth Tran, Lea M D Delbridge, Anthony J R Hickey, Eric Hanssen, Edmund J Crampin, Vijay Rajagopal
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 12, p e1006640 (2018)
Recent electron microscopy data have revealed that cardiac mitochondria are not arranged in crystalline columns but are organised with several mitochondria aggregated into columns of varying sizes spanning the cell cross-section. This raises the ques
Externí odkaz:
https://doaj.org/article/685ae461511743d199a4935553e960f2