GLAD-PCR Assay of R(5mC)GY Sites in the Regulatory Region of Tumor-Suppressor Genes Associated with Gastric Cancer

Autor: Malyshev, B. S., Netesova, N. A., Smetannikova, N. A., Abdurashitov, M. A., Akishev, A. G., Dubinin, E. V., Azanov, A. Z., Vihlyanov, I. V., Nikitin, M. K., Karpov, A. B., Degtyarev, S. Kh.

Publikováno v: Acta Naturae

At early stages of carcinogenesis, the regulatory regions of some tumor suppressor genes become aberrantly methylated at RCGY sites, which are substrates of DNA methyltransferase Dnmt3. Identification of aberrantly methylated sites in tumor DNA is co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6876d419c8f2e7402b08d083c7d8e265
http://europepmc.org/articles/PMC7604892

[Application of GLAD-PCR Assay for Study on DNA Methylation in Regulatory Regions of Some Tumor-Suppressor Genes in Lung Cancer].

Autor: Smetannikova NA; State Research Center of Virology and Biotechnology, Koltsovo, Russia.; EpiGene LLC, Novosibirsk, Russia., Evdokimov AA; State Research Center of Virology and Biotechnology, Koltsovo, Russia.; EpiGene LLC, Novosibirsk, Russia., Netesova NA; State Research Center of Virology and Biotechnology, Koltsovo, Russia.; EpiGene LLC, Novosibirsk, Russia., Abdurashitov MA; EpiGene LLC, Novosibirsk, Russia., Akishev AG; EpiGene LLC, Novosibirsk, Russia., Dubinin EV; EpiGene LLC, Novosibirsk, Russia., Pozdnyakov PI; State Research Center of Virology and Biotechnology, Koltsovo, Russia., Vihlyanov IV; Altai Regional Oncology Center, Barnaul, Russia., Nikitin MK; Altai Regional Oncology Center, Barnaul, Russia., Topolnitsky EB; Tomsk Regional Clinical Hospital, Tomsk, Russia., Karpov AB; Seversk Biophysical Research Centre, Seversk, Russia., Kolomiets SA; Regional Clinical Oncology Center, Kemerovo, Russia., Degtyarev SK; EpiGene LLC, Novosibirsk, Russia.

Publikováno v: Zhongguo fei ai za zhi = Chinese journal of lung cancer [Zhongguo Fei Ai Za Zhi] 2019 Sep 20; Vol. 22 (9), pp. 551-561.