Zobrazeno 1 - 10
of 739
pro vyhledávání: '"Vihinen Mauno"'
Autor:
Velasquez, Erika, Savchenko, Ekaterina, Marmolejo-Martínez-Artesero, Sara, Challuau, Désiré, Aebi, Aline, Pomeshchik, Yuriy, Lamas, Nuno Jorge, Vihinen, Mauno, Rezeli, Melinda, Schneider, Bernard, Raoul, Cedric, Roybon, Laurent
Publikováno v:
In Neurobiology of Disease 15 October 2024 201
Autor:
Vihinen Mauno
Publikováno v:
BMC Genomics, Vol 13, Iss Suppl 4, p S2 (2012)
Abstract Background Prediction methods are increasingly used in biosciences to forecast diverse features and characteristics. Binary two-state classifiers are the most common applications. They are usually based on machine learning approaches. For th
Externí odkaz:
https://doaj.org/article/e05180202b4a460bab58fe2b35d08d47
Autor:
Byrne Myles, Fokkema Ivo FAC, Lancaster Owen, Adamusiak Tomasz, Ahonen-Bishopp Anni, Atlan David, Béroud Christophe, Cornell Michael, Dalgleish Raymond, Devereau Andrew, Patrinos George P, Swertz Morris A, Taschner Peter EM, Thorisson Gudmundur A, Vihinen Mauno, Brookes Anthony J, Muilu Juha
Publikováno v:
BMC Bioinformatics, Vol 13, Iss 1, p 254 (2012)
Abstract Background Sharing of data about variation and the associated phenotypes is a critical need, yet variant information can be arbitrarily complex, making a single standard vocabulary elusive and re-formatting difficult. Complex standards have
Externí odkaz:
https://doaj.org/article/ef3d377fc28f4c09a1c5a1aca6db1776
Autor:
Tammela Teuvo LJ, Oja Hannu, Vihinen Mauno, Ikonen Tarja, Isotalo Jarkko, Schindler Martin, Mattila Henna, Wahlfors Tiina, Schleutker Johanna
Publikováno v:
BMC Cancer, Vol 11, Iss 1, p 327 (2011)
Abstract Background Several predisposition loci for hereditary prostate cancer (HPC) have been suggested, including HPCX1 at Xq27-q28, but due to the complex structure of the region, the susceptibility gene has not yet been identified. Methods In thi
Externí odkaz:
https://doaj.org/article/6f8138045c7e49f98d5c67c6e45a7c75
Autor:
Laurila Kirsti, Vihinen Mauno
Publikováno v:
BMC Genomics, Vol 10, Iss 1, p 122 (2009)
Abstract Background Eukaryotic cells contain numerous compartments, which have different protein constituents. Proteins are typically directed to compartments by short peptide sequences that act as targeting signals. Translocation to the proper compa
Externí odkaz:
https://doaj.org/article/07380c2358d541bc84d275ca6ec5e054
Autor:
Vihinen Mauno, Ortutay Csaba
Publikováno v:
BMC Immunology, Vol 10, Iss 1, p 3 (2009)
Abstract Background Functioning of the immune system requires the coordinated expression and action of many genes and proteins. With the emergence of high-throughput technologies, a great amount of molecular data is available for the genes and protei
Externí odkaz:
https://doaj.org/article/3413ba0815594fbaa09c3b7f5ff83933
Autor:
Kytömäki Leena, Salenius Juha-Pekka, Vihinen Mauno, Thusberg Janita, Oksala Niku, Järvinen Otso, Kajander Olli A, Ilveskoski Erkki, Mikkelsson Jussi, Karhunen Pekka J, Levula Mari, Fan Yue-Mei, Soini Juhani T, Laaksonen Reijo, Lehtimäki Terho
Publikováno v:
Thrombosis Journal, Vol 6, Iss 1, p 17 (2008)
Abstract Background Disturbed cellular cholesterol homeostasis may lead to accumulation of cholesterol in human atheroma plaques. Cellular cholesterol homeostasis is controlled by the sterol regulatory element-binding transcription factor 2 (SREBF-2)
Externí odkaz:
https://doaj.org/article/0cc559637656432cb2861500ca06ae93
Autor:
Vihinen Mauno, Ortutay Csaba
Publikováno v:
BMC Bioinformatics, Vol 9, Iss 1, p 299 (2008)
Abstract Background Pseudogenes, nonfunctional copies of genes, evolve fast due the lack of evolutionary pressures and thus appear in several different forms. PseudoGeneQuest is an online tool to search the human genome for a given query sequence and
Externí odkaz:
https://doaj.org/article/5bb0f71f0e82467d92b6615b452a9d1a
Publikováno v:
BMC Bioinformatics, Vol 7, Iss 1, p 484 (2006)
Abstract Background Multiple sequence alignment is the foundation of many important applications in bioinformatics that aim at detecting functionally important regions, predicting protein structures, building phylogenetic trees etc. Although the auto
Externí odkaz:
https://doaj.org/article/dcf362532cf8437bb7a1e1cefdc5e500
Publikováno v:
BMC Bioinformatics, Vol 6, Iss 1, p 215 (2005)
Abstract Background Cells react to changing intra- and extracellular signals by dynamically modulating complex biochemical networks. Cellular responses to extracellular signals lead to changes in gene and protein expression. Since the majority of gen
Externí odkaz:
https://doaj.org/article/f9b2ada78de346d9a7c6b329c3bec131