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Akademický článek

Sub-chronic (13-week) oral toxicity study in rats with recombinant human lactoferrin produced in the milk of transgenic cows

Autor: Appel, M.J., van Veen, H.A., Vietsch, H., Salaheddine, M., Nuijens, J.H., Ziere, B., de Loos, F.

Publikováno v: In Food and Chemical Toxicology 2006 44(7):964-973

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Targeted delivery of oligodeoxynucleotides to parenchymal liver cells in vivo

Autor: Biessen, E A, Vietsch, H, Rump, E T, Fluiter, K, Kuiper, J, Bijsterbosch, M K, van Berkel, T J

Publikováno v: Biochemical journal, 340 ( Pt 3), 783-792. Portland Press Ltd.

Anti-sense oligodeoxynucleotides (ODNs) hold great promise for correcting the biosynthesis of clinically relevant proteins. The potential of ODNs for modulating liver-specific genes might be increased by preventing untimely elimination and by improvi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::01c1854229351f5c03cd0c51f02fceb3
https://pure.amc.nl/en/publications/targeted-delivery-of-oligodeoxynucleotides-to-parenchymal-liver-cells-in-vivo(429aa312-b018-47f4-a491-19abc02cb356).html

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Prolonged circulation of tissue-type plasminogen activator in vivo by blocking mannose receptor- and lrp-mediated liver uptake

Autor: Kuiper, J., Teijlingen, M. van, Vietsch, H., Rijken, D.C., Berkel, T.J.C. van, Blessen, E.A.L.

Publikováno v: Fibrinolysis, SUPPL. 3, 10, 6

A major complication of the use of of tissue-type plasminogen activator (t-PA) as fibrinolytic agent is its rapid clearance from the bloodstream. We have studied whether t-PA clearance can be reduced by preventing receptor-mediated endocytosis of t-P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f5083fb6ac624e4b5549ef8db758f3b2
http://resolver.tudelft.nl/uuid:09ea2255-99f0-4dea-bf42-f9f0fc4590b1

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