Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Viera Miskovska"'
Autor:
Katarina Kalavska, Zuzana Sestakova, Andrea Mlcakova, Paulina Gronesova, Viera Miskovska, Katarina Rejlekova, Daniela Svetlovska, Zuzana Sycova-Mila, Jana Obertova, Patrik Palacka, Jozef Mardiak, Miroslav Chovanec, Michal Chovanec, Michal Mego
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The pattern of immune cell distribution in testicular germ cell tumors (GCT) significantly differs from the immune environment in normal testicular tissues. The present study aimed to evaluate the role of different leukocyte subpopulation in GCTs. A
Externí odkaz:
https://doaj.org/article/9c04b63fe92a4f1993d3dd27de6da4ca
Autor:
Katarina Kalavska, Zuzana Sestakova, Andrea Mlcakova, Paulina Gronesova, Viera Miskovska, Katarina Rejlekova, Daniela Svetlovska, Zuzana Sycova-Mila, Jana Obertova, Patrik Palacka, Jozef Mardiak, Miroslav Chovanec, Michal Chovanec, Michal Mego
Publikováno v:
Life, Vol 12, Iss 5, p 678 (2022)
The tumor microenvironment (TME) and the host inflammatory response are closely interconnected. The interplay between systemic inflammation and the local immune response may influence tumor development and progression in various types of cancer. The
Externí odkaz:
https://doaj.org/article/367ab3bb9108473ea0b1e0d0af88d0de
Autor:
Michal Chovanec, Zuzana Cierna, Viera Miskovska, Katarina Machalekova, Katarina Kalavska, Katarina Rejlekova, Daniela Svetlovska, Dusan Macak, Stanislav Spanik, Karol Kajo, Pavel Babal, Michal Mego, Jozef Mardiak
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background WNT/βcatenin (WNTβ) pathway is activated in early stages of embryonic development. We aimed to evaluate the significance of βcatenin in germ cell tumors (GCTs) and explore associations with the inflamed environment. Methods Sur
Externí odkaz:
https://doaj.org/article/e2bedfd776a24a93b149c36fc239cb18
Autor:
Patrik Palacka, Lenka Hurbanova, Katarina Kalavska, Michal Mego, Paulina Gronesova, Viera Miskovska, Jana Obertova, Michal Chovanec, Daniela Svetlovska, Andrea Mlcakova, Zuzana Sestakova, Katarína Kozics, Katarina Rejlekova, Zuzana Sycova-Mila, Jozef Mardiak, Miroslav Chovanec
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 15
International Journal of Molecular Sciences, Vol 22, Iss 8281, p 8281 (2021)
Volume 22
Issue 15
International Journal of Molecular Sciences, Vol 22, Iss 8281, p 8281 (2021)
Chemoresistance of germ cell tumors (GCTs) represents an intensively studied property of GCTs that is the result of a complicated multifactorial process. One of the driving factors in this process is the tumor microenvironment (TME). Intensive crosst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8aa246e89afe767c3961ca2c47f7cdf
https://pubmed.ncbi.nlm.nih.gov/34361047
https://pubmed.ncbi.nlm.nih.gov/34361047
Autor:
Katarina Machalekova, Karol Kajo, Pavel Babal, Michal Chovanec, Katarina Kalavska, Viera Miskovska, Michal Mego, Jozef Mardiak, Zuzana Cierna, Katarina Rejlekova, Stanislav Spanik, Ugo De Giorgi, Daniela Svetlovska, Dusan Macak
Publikováno v:
British Journal of Cancer
Background: We evaluated systemic immune-inflammation index (SII) and its association with patient outcome in germ-cell tumours (GCTs). Methods: Two independent cohorts of patients were analysed; the discovery set (n=171) from a single institution an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2417989b863e4b946229703dc156ec4
http://europepmc.org/articles/PMC5877428
http://europepmc.org/articles/PMC5877428
Autor:
Lucia Kucerova, Michal Mego, Verona Buocikova, Miroslava Matuskova, Svetlana Miklikova, Silvia Schmidtova, Zuzana Cierna, Bozena Smolkova, Katarina Kalavska, Michal Chovanec, Viera Miskovska, Katarina Gercakova, Monika Burikova, Erika Durinikova
Publikováno v:
Cancers
Cancers, Vol 11, Iss 9, p 1224 (2019)
Volume 11
Issue 9
Cancers, Vol 11, Iss 9, p 1224 (2019)
Volume 11
Issue 9
Cisplatin resistance in testicular germ cell tumors (TGCTs) is a clinical challenge. We investigated the underlying mechanisms associated with cancer stem cell (CSC) markers and modalities circumventing the chemoresistance. Chemoresistant models (des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7cc492e948c1f867465cc9e7ed10eb
http://europepmc.org/articles/PMC6769487
http://europepmc.org/articles/PMC6769487
Autor:
Michal Mego, Daniela Svetlovska, Dalibor Ondrus, Michal Chovanec, Katarina Rejlekova, Stanislav Spanik, Katarina Hainova, Zuzana Cierna, Jozef Mardiak, Dusan Macak, Katarina Machalekova, Karol Kajo, Viera Miskovska, Pavel Babal
Publikováno v:
Annals of Oncology. 27:300-305
BACKGROUND Testicular germ cell tumors (TGCTs) belong to the most chemosensitive solid tumors; however, a small proportion of patients fail to be cured with cisplatin-based chemotherapy. Inhibitors of PD-1/PD-L1 pathways represent a new class of prom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3acd57e9d9f7c5931e3109d72bc9ef
https://doi.org/10.1093/annonc/mdv574
https://doi.org/10.1093/annonc/mdv574
Autor:
Viera Miskovska, Zuzana Sycova-Mila, V. De Angelis, Michal Mego, Jozef Mardiak, Jana Obertova, Katarina Rejlekova, Patrik Palacka, Daniela Svetlovska, Katarina Kalavska, Michal Chovanec
Publikováno v:
Annals of Oncology. 31:S600
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15a590e95264c484716d7aba26ed159e
https://doi.org/10.1016/j.annonc.2020.08.858
https://doi.org/10.1016/j.annonc.2020.08.858
Management of clinical stage I testicular seminoma: active surveillance versus adjuvant chemotherapy
Autor:
K. Szoldova, Dalibor Ondrus, Karol Kajo, V. Stastna, Martina Ondrušová, Viera Miskovska, Vanda Usakova
Publikováno v:
International Urology and Nephrology. 47:1143-1147
Surveillance after orchiectomy alone has become popular in the management of clinical stage I nonseminomatous germ cell testicular tumors (CSI NSGCTT), and adjuvant chemotherapy has been accepted in high-risk CSI NSGCTT. Because of the late toxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::238518e97f76ce15f02996b86e87b996
https://doi.org/10.1007/s11255-015-1002-4
https://doi.org/10.1007/s11255-015-1002-4
Autor:
Viera Miskovska, Michal Chovanec, Jana Obertova, Stanislav Spanik, Michal Mego, Jan Rajec, Katarina Kalavska, Dana Cholujova, Silvia Cingelova, Dalibor Ondrus, Daniela Svetlovska, Zuzana Sycova-Mila, Patrik Palacka, Jan Luha, Vanda Usakova, Paulina Gronesova, Jozef Mardiak
Publikováno v:
Clinical genitourinary cancer. 15(3)
Cytokines are the communicators of immune system and are involved in all immune responses. The aim of this study was to assess the correlation among plasma cytokines, patient and tumor characteristics, and clinical outcome in chemonaive testicular ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d35e058f8288e790b6cbaae0701ee582
https://pubmed.ncbi.nlm.nih.gov/28237180
https://pubmed.ncbi.nlm.nih.gov/28237180