Cystargolide-based amide and ester Pz analogues as proteasome inhibitors and anti-cancer agents.

Autor: Viera CR; Department of Chemistry, New Mexico Institute of Mining and Technology, Socorro, NM 87801, USA., Stevens BT; Department of Biology, New Mexico Institute of Mining and Technology, Socorro, NM 87801, USA., Viera T; Department of Chemistry, New Mexico Institute of Mining and Technology, Socorro, NM 87801, USA., Zielinski C; Department of Chemical Engineering, New Mexico Institute of Mining and Technology, Socorro, NM 87801, USA., Uranga LA; Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA., Rogelj S; Department of Biology, New Mexico Institute of Mining and Technology, Socorro, NM 87801, USA., Patidar PL; Department of Chemistry, New Mexico Institute of Mining and Technology, Socorro, NM 87801, USA., Tello-Aburto R; Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, NM 88003, USA.

Publikováno v: Royal Society open science [R Soc Open Sci] 2022 Sep 28; Vol. 9 (9), pp. 220358. Date of Electronic Publication: 2022 Sep 28 (Print Publication: 2022).

MYC/PGC-1α Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells.

Autor: Sancho P; Centre for Stem Cells in Cancer & Ageing, Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK; Stem Cells & Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain. Electronic address: p.sancho@qmul.ac.uk., Burgos-Ramos E; Stem Cells & Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain., Tavera A; Stem Cells & Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain., Bou Kheir T; Centre for Stem Cells in Cancer & Ageing, Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK., Jagust P; Centre for Stem Cells in Cancer & Ageing, Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK., Schoenhals M; Centre for Stem Cells in Cancer & Ageing, Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK., Barneda D; Centre for Stem Cells in Cancer & Ageing, Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK., Sellers K; The Francis Crick Institute, Mill Hill Laboratories, The Ridgeway, London NW7 1AA, UK., Campos-Olivas R; Spectroscopy and NMR Unit, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain., Graña O; Bioinformatics Unit and Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain., Viera CR; Stem Cells & Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain., Yuneva M; The Francis Crick Institute, Mill Hill Laboratories, The Ridgeway, London NW7 1AA, UK., Sainz B Jr; Stem Cells & Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain., Heeschen C; Centre for Stem Cells in Cancer & Ageing, Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK; Stem Cells & Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain. Electronic address: c.heeschen@qmul.ac.uk.

Publikováno v: Cell metabolism [Cell Metab] 2015 Oct 06; Vol. 22 (4), pp. 590-605. Date of Electronic Publication: 2015 Sep 10.

Cancer stem cells in meningiomas: novel insights and therapeutic implications.

Autor: Awuah WA; Faculty of Medicine, Sumy State University, Sumy, 40007, Ukraine., Ben-Jaafar A; School of Medicine, University College Dublin, Belfield, Dublin 4, Ireland., Karkhanis S; School of Medicine, Queen's University Belfast, Belfast, UK., Nkrumah-Boateng PA; University of Ghana Medical School, Accra, Ghana., Kong JSH; School of Medicine, College of Medical & Veterinary Life Sciences, University of Glasgow, Glasgow, UK., Mannan KM; School of Medicine, Queen's University Belfast, Dentistry & Biomedical Sciences, Belfast, UK., Shet V; University of Connecticut New Britain Program, New Britain, Connecticut, USA., Imran S; School of Medicine, Queen's University Belfast, Dentistry & Biomedical Sciences, Belfast, UK., Bone M; Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Salford, UK., Boye ANA; University of Ghana Medical School, Accra, Ghana., Ranganathan S; Department of Medicine, University of Cambridge, Cambridge, UK., Shah MH; School of Medicine, Queen's University Belfast, Belfast, UK. mshah03@qub.ac.uk., Abdul-Rahman T; Faculty of Medicine, Sumy State University, Sumy, 40007, Ukraine., Atallah O; Department of Neurosurgery, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625, Hannover, Germany.

Publikováno v: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico [Clin Transl Oncol] 2024 Sep 24. Date of Electronic Publication: 2024 Sep 24.

Multifaceted roles of mitochondrial dysfunction in diseases: from powerhouses to saboteurs.

Autor: Prabhu, Surapriya Surendranath, Nair, Aathira Sujathan, Nirmala, Saiprabha Vijayakumar

Publikováno v: Archives of Pharmacal Research; Oct2023, Vol. 46 Issue 9/10, p723-743, 21p

Reprogramming Oxidative Phosphorylation in Cancer: A Role for RNA-Binding Proteins.

Autor: Esparza-Moltó, Pau B., Cuezva, José M.

Publikováno v: Antioxidants & Redox Signaling; 11/1/2020, Vol. 33 Issue 13, p927-945, 19p