Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Vien Holcombe"'
Autor:
Ning Qin, Wolfgang Baehr, Rehwa H. Lee, Vien Holcombe, Richard L. Hurwitz, Steven J. Pittler, Cheryl M. Craft, Gail C. Wright, Richard N. Lolley, Michael L. Suber
Publikováno v:
Proceedings of the National Academy of Sciences. 90:3968-3972
Irish setter dogs affected with a rod/cone dysplasia (locus designation, rcd1) display markedly elevated levels of retinal cGMP during postnatal development. The photoreceptor degeneration commences approximately 25 days after birth and culminates at
Publikováno v:
Journal of Biological Chemistry. 265:8901-8907
A calmodulin (CaM)-dependent phosphodiesterase activity that hydrolyzes both cGMP and cAMP was observed in anion exchange high performance liquid chromatography (HPLC) profiles from phytohemagglutinin-stimulated mononuclear cells but not in profiles
Autor:
Kathryn Louie, Pamela Schafer, Patricia Chévez-Barrios, Karen T. Marcus, Mary Y. Hurwitz, C. Estuardo Aguilar-Cordova, Vien Holcombe, Richard L. Hurwitz
Publikováno v:
The American journal of pathology. 157(4)
To generate animal models of retinoblastoma that closely resemble metastatic and nonmetastatic human disease for the purposes of examining tumor biology and developing alternate treatments, human retinoblastoma cell lines were injected into the vitre
Autor:
Richard L. Hurwitz, Vien Holcombe
Publikováno v:
Journal of Biological Chemistry. 266:7975-7977
The cGMP-gated cation channel is a member of a new family of channel proteins that appear to be directly regulated by cyclic nucleotides. A protein with a subunit molecular mass of 78 kDa that exhibits cGMP-gated calcium flux when reconstituted into