Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Vidya K Nagalakshmi"'
Autor:
Brian C. Belyea, Araceli E. Santiago, Wilson A. Vasconez, Vidya K. Nagalakshmi, Fang Xu, Theodore C. Mehalic, Maria Luisa S. Sequeira-Lopez, R. Ariel Gomez
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The hormone renin plays a crucial role in the regulation of blood pressure and fluid-electrolyte homeostasis. Normally, renin is synthesized by juxtaglomerular (JG) cells, a specialized group of myoepithelial cells located near the entrance
Externí odkaz:
https://doaj.org/article/660db11b5d0e49efb6c0e8f6c7c6430b
Autor:
Vidya K Nagalakshmi, Minghong Li, Silvia Medrano, Roberto A Gomez, Maria Luisa S Sequeira-Lopez
Publikováno v:
Hypertension. 79
Renin, the rate-limiting enzyme of the renin-angiotensin system, is increased in the kidneys subjected to ureteral obstruction. We elucidated the changes and contribution of renin-producing cells (RPCs) and the cells of renin lineage (CoRL) during ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b15d1e86d6cd1089c3b511e6ff7e71f
https://doi.org/10.1161/hyp.79.suppl_1.090
https://doi.org/10.1161/hyp.79.suppl_1.090
Autor:
Hirofumi Watanabe, Mark D. Okusa, Matthew R. Tolerico, Vidya K. Nagalakshmi, Maria Luisa S. Sequeira-Lοpez, Shinji Tanaka, Ichiei Narita, Robert L. Paxton, Seiji Watanabe, Shin Goto, R. Ariel Gomez
Publikováno v:
Am J Physiol Renal Physiol
The acyl-CoA synthetase medium-chain family member 2 ( Acsm2) gene was first identified and cloned by our group as a kidney-specific “ KS” gene. However, its expression pattern and function remain to be clarified. In the present study, we found t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f369c523888b2a9cc6af655df90e593
https://doi.org/10.1152/ajprenal.00348.2020
https://doi.org/10.1152/ajprenal.00348.2020
Autor:
Joseph C. Gigliotti, Vidya K. Nagalakshmi, R. Ariel Gomez, Frederick H. Epstein, Alexander L. Klibanov, Robert L. Chevalier, Maria Luisa S. Sequeira-Lopez, Soham Shah, Minghong Li
Publikováno v:
Clinical Science. 132:2519-2545
Congenital obstructive nephropathy is a major cause of chronic kidney disease (CKD) in children. The contribution of changes in the identity of renal cells to the pathology of obstructive nephropathy is poorly understood. Using a partial unilateral u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c793a70e7a4b399332713cc59b0ccfe
https://doi.org/10.1042/cs20180623
https://doi.org/10.1042/cs20180623
Autor:
Maria Luisa S. Sequeira-Lopez, Vidya K. Nagalakshmi, Theodore C. Mehalic, Wilson A. Vasconez, Brian C. Belyea, Araceli E. Santiago, Fang Xu, R. Ariel Gomez
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
The hormone renin plays a crucial role in the regulation of blood pressure and fluid-electrolyte homeostasis. Normally, renin is synthesized by juxtaglomerular (JG) cells, a specialized group of myoepithelial cells located near the entrance to the ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c7b5154b9998986e669eca9ae67617c
https://doi.org/10.1038/s41598-021-86629-w
https://doi.org/10.1038/s41598-021-86629-w
Autor:
Maria Luisa S. Sequeira-Lopez, Wilson A. Vasconez, Vidya K. Nagalakshmi, R. Ariel Gomez, Theodore C. Mehalic, Brian C. Belyea, Araceli E. Santiago
The hormone renin plays a crucial role in the regulation of blood pressure and fluid-electrolyte homeostasis. Normally, renin is synthesized by juxtaglomerular (JG) cells, a specialized group of myoepithelial cells located near the entrance to the ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dbdea706028a7927fb9fd3976e0881c
https://doi.org/10.1101/770511
https://doi.org/10.1101/770511
Autor:
Jing Yu, Vidya K. Nagalakshmi
Publikováno v:
Molecular Reproduction and Development. 82:151-166
The mammalian metanephric kidney is composed of two epithelial components, the collecting duct system and the nephron epithelium, that differentiate from two different tissues -the ureteric bud epithelium and the nephron progenitors, respectively-of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0831086e4fec39d86590453ad7c2a7c
https://doi.org/10.1002/mrd.22462
https://doi.org/10.1002/mrd.22462
Publikováno v:
Developmental Dynamics. 244:444-456
Background: Our previous study on mouse mutants with the ureteric bud (UB) epithelium-specific Dicer deletion (Dicer UB mutants) demonstrated the significance of UB epithelium-derived miRNAs in UB development. Results: Our whole-genome transcriptiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8e37c55a1b4f32c611ee7acccf950d8
https://doi.org/10.1002/dvdy.24221
https://doi.org/10.1002/dvdy.24221
Publikováno v:
Hypertension. 68
Tubular degeneration, loss of renal tubules and interstitial fibrosis due to kidney injury lead to chronic renal disease and hypertension. Using a partial unilateral ureteral obstruction (pUUO) model in neonatal mice, we analyzed the fate cell change
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ea3262238459fd68c835a275ee96f8f
https://doi.org/10.1161/hyp.68.suppl_1.061
https://doi.org/10.1161/hyp.68.suppl_1.061
Autor:
Maria Luisa S Sequeira Lopez, Vidya K Nagalakshmi, Minghong Li, Curt D Sigmund, R. Ariel Gomez
Publikováno v:
Hypertension. 66
Renin, the key regulated enzyme of the renin angiotensin system regulates blood pressure and fluid electrolyte homeostasis as well as morphogenesis of the kidney. Classically, renin is synthesized and released from juxtaglomerular cells located in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3236123456e55be9f269f05203e7feac
https://doi.org/10.1161/hyp.66.suppl_1.mp01
https://doi.org/10.1161/hyp.66.suppl_1.mp01